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PMC Full-Text Search Results

Items: 1 to 20 of 1887

1.
The heterochronic LIN-14 protein is a BEN domain transcription factor
Sharrell Greene, Ji Huang, Keith Hamilton, Liang Tong, Oliver Hobert, HaoSheng Sun
Curr Biol. Author manuscript; available in PMC 2023 Apr 7.
Published in final edited form as: Curr Biol. 2023 Mar 27; 33(6): R217–R218. doi: 10.1016/j.cub.2023.02.016
PMCID:
PMC10080584
ArticlePubReaderPDF–666KCite
2.
A chromosome-level reference genome and pangenome for barn swallow population genomics
Simona Secomandi, Guido R. Gallo, Marcella Sozzoni, Alessio Iannucci, Elena Galati, Linelle Abueg, Jennifer Balacco, Manuela Caprioli, William Chow, Claudio Ciofi, Joanna Collins, Olivier Fedrigo, Luca Ferretti, Arkarachai Fungtammasan, Bettina Haase, Kerstin Howe, Woori Kwak, Gianluca Lombardo, Patrick Masterson, Graziella Messina, Anders P. Møller, Jacquelyn Mountcastle, Timothy A. Mousseau, Joan Ferrer Obiol, Anna Olivieri, Arang Rhie, Diego Rubolini, Marielle Saclier, Roscoe Stanyon, David Stucki, Françoise Thibaud-Nissen, James Torrance, Antonio Torroni, Kristina Weber, Roberto Ambrosini, Andrea Bonisoli-Alquati, Erich D. Jarvis, Luca Gianfranceschi, Giulio Formenti
Cell Rep. Author manuscript; available in PMC 2023 Mar 28.
Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111992. Published online 2023 Jan 19. doi: 10.1016/j.celrep.2023.111992
PMCID:
PMC10044405
ArticlePubReaderPDF–3.0MCite
3.
Molecular and spatial signatures of mouse brain aging at single-cell resolution
William E. Allen, Timothy R. Blosser, Zuri A. Sullivan, Catherine Dulac, Xiaowei Zhuang
Cell. Author manuscript; available in PMC 2023 Mar 18.
Published in final edited form as: Cell. 2023 Jan 5; 186(1): 194–208.e18. Published online 2022 Dec 28. doi: 10.1016/j.cell.2022.12.010
PMCID:
PMC10024607
ArticlePubReaderPDF–3.9MCite
4.
FGF21 Counteracts Alcohol Intoxication by Activating the Noradrenergic Nervous System
Mihwa Choi, Marc Schneeberger, Wei Fan, Abhijit Bugde, Laurent Gautron, Kevin Vale, Robert E. Hammer, Yuan Zhang, Jeffrey M. Friedman, David J. Mangelsdorf, Steven A. Kliewer
Cell Metab. Author manuscript; available in PMC 2023 Mar 13.
Published in final edited form as: Cell Metab. 2023 Mar 7; 35(3): 429–437.e5. doi: 10.1016/j.cmet.2023.02.005
PMCID:
PMC10009780
ArticlePubReaderPDF–3.6MCite
5.
Robust deep learning based protein sequence design using ProteinMPNN
J. Dauparas, I. Anishchenko, N. Bennett, H. Bai, R. J. Ragotte, L. F. Milles, B. I. M. Wicky, A. Courbet, R. J. de Haas, N. Bethel, P. J. Y. Leung, T. F. Huddy, S. Pellock, D. Tischer, F. Chan, B. Koepnick, H. Nguyen, A. Kang, B. Sankaran, A. K. Bera, N. P. King, D. Baker
Science. Author manuscript; available in PMC 2023 Mar 9.
Published in final edited form as: Science. 2022 Oct 7; 378(6615): 49–56. Published online 2022 Sep 15. doi: 10.1126/science.add2187
PMCID:
PMC9997061
ArticlePubReaderPDF–1.8MCite
6.
A Conformational Change in the N Terminus of SLC38A9 Signals mTORC1 Activation
Hsiang-Ting Lei, Xuelang Mu, Johan Hattne, Tamir Gonen
Structure. Author manuscript; available in PMC 2023 Mar 8.
Published in final edited form as: Structure. 2021 May 6; 29(5): 426–432.e8. Published online 2020 Dec 8. doi: 10.1016/j.str.2020.11.014
PMCID:
PMC9994763
ArticlePubReaderPDF–1.3MCite
7.
Structures of a Mobile Intron Retroelement Poised to Attack Its Structured DNA Target
Kevin Chung, Ling Xu, Pengxin Chai, Junhui Peng, Swapnil C. Devarkar, Anna Marie Pyle
Science. Author manuscript; available in PMC 2023 May 17.
Published in final edited form as: Science. 2022 Nov 11; 378(6620): 627–634. Published online 2022 Nov 10. doi: 10.1126/science.abq2844
PMCID:
PMC10190682
ArticlePubReaderPDF–2.0MCite
8.
The contribution of historical processes to contemporary extinction risk in placental mammals
Aryn P. Wilder, Megan A Supple, Ayshwarya Subramanian, Anish Mudide, Ross Swofford, Aitor Serres-Armero, Cynthia Steiner, Klaus-Peter Koepfli, Diane P. Genereux, Elinor K. Karlsson, Kerstin Lindblad-Toh, Tomas Marques-Bonet, Violeta Munoz Fuentes, Kathleen Foley, Wynn K. Meyer, Zoonomia Consortium, Oliver A. Ryder, Beth Shapiro
Science. Author manuscript; available in PMC 2023 May 15.
Published in final edited form as: Science. 2023 Apr 28; 380(6643): eabn5856. Published online 2023 Apr 28. doi: 10.1126/science.abn5856
PMCID:
PMC10184782
ArticlePubReaderPDF–944KCite
9.
A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery
Liang Meng Wee, Alexander B. Tong, Alfredo Jose Florez Ariza, Cristhian Cañari-Chumpitaz, Patricia Grob, Eva Nogales, Carlos Bustamante
Cell. Author manuscript; available in PMC 2023 Apr 27.
Published in final edited form as: Cell. 2023 Mar 16; 186(6): 1244–1262.e34. doi: 10.1016/j.cell.2023.02.008
PMCID:
PMC10135430
ArticlePubReaderPDF–2.7MCite
10.
Molecular Structures Reveal Synergistic Rescue of Δ508 CFTR by Trikafta Modulators
Karol Fiedorczuk, Jue Chen
Science. Author manuscript; available in PMC 2023 Feb 10.
Published in final edited form as: Science. 2022 Oct 21; 378(6617): 284–290. Published online 2022 Oct 20. doi: 10.1126/science.ade2216
PMCID:
PMC9912939
ArticlePubReaderPDF–1.0MCite
11.
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity
Brittany L. Hartwell, Mariane B. Melo, Peng Xiao, Ashley A. Lemnios, Na Li, Jason Y.H. Chang, Jingyou Yu, Makda S. Gebre, Aiquan Chang, Laura Maiorino, Crystal Carter, Tyson J. Moyer, Neil C. Dalvie, Sergio A. Rodriguez-Aponte, Kristen A. Rodrigues, Murillo Silva, Heikyung Suh, Josetta Adams, Jane Fontenot, J. Christopher Love, Dan H. Barouch, Francois Villinger, Ruth M. Ruprecht, Darrell J. Irvine
Sci Transl Med. Author manuscript; available in PMC 2023 Jan 12.
Published in final edited form as: Sci Transl Med. 2022 Jul 20; 14(654): eabn1413. Published online 2022 Jul 20. doi: 10.1126/scitranslmed.abn1413
PMCID:
PMC9835395
ArticlePubReaderPDF–2.6MCite
12.
LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages
Zheng Wei, Joonseok Oh, Richard A Flavell, Jason M. Crawford
Nature. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Nature. 2022 Sep; 609(7926): 348–353. Published online 2022 Aug 17. doi: 10.1038/s41586-022-05111-3
Correction in:
Nature. 2023 May 25
PMCID:
PMC9813773
ArticlePubReaderPDF–2.6MCite
13.
Maternal H3K27me3 controls DNA methylation-independent genomic imprinting
Azusa Inoue, Lan Jiang, Lu Falong, Tsukasa Suzuki, Yi Zhang
Nature. Author manuscript; available in PMC 2022 Nov 18.
Published in final edited form as: Nature. 2017 Jul 27; 547(7664): 419–424. Published online 2017 Jul 19. doi: 10.1038/nature23262
PMCID:
PMC9674007
ArticlePubReaderPDF–2.7MCite
14.
Reconfigurable asymmetric protein assemblies through implicit negative design
Danny D. Sahtoe, Florian Praetorius, Alexis Courbet, Yang Hsia, Basile I.M. Wicky, Natasha I. Edman, Lauren M. Miller, Bart J. R. Timmermans, Justin Decarreau, Hana M. Morris, Alex Kang, Asim K. Bera, David Baker
Science. Author manuscript; available in PMC 2023 Jan 27.
Published in final edited form as: Science. 2022 Jan 21; 375(6578): eabj7662. Published online 2022 Jan 21. doi: 10.1126/science.abj7662
PMCID:
PMC9881579
ArticlePubReaderPDF–1.8MCite
15.
A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability
Keelan Z. Guiley, Kevan M. Shokat
Cancer Discov. 2023 Jan 9; 13(1): 56–69. Published online 2022 Oct 5. doi: 10.1158/2159-8290.CD-22-0381
PMCID:
PMC9827106
ArticlePubReaderPDF–27MCite
16.
A rapid RIG-I signaling relay mediates efficient antiviral response
Daniel T. Thoresen, Drew Galls, Benjamin Götte, Wenshuai Wang, Anna M. Pyle
Mol Cell. Author manuscript; available in PMC 2023 Jan 8.
Published in final edited form as: Mol Cell. 2022 Dec 6 : S1097-2765(22)01131-5. Published online 2022 Dec 6. doi: 10.1016/j.molcel.2022.11.018
PMCID:
PMC9825657
ArticlePubReaderPDF–1.3MCite
17.
Spatially resolved single-cell genomics and transcriptomics by imaging
Xiaowei Zhuang
Nat Methods. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Nat Methods. 2021 Jan; 18(1): 18–22. doi: 10.1038/s41592-020-01037-8
PMCID:
PMC9805800
ArticlePubReaderPDF–870KCite
18.
Hallucinating symmetric protein assemblies
B. I. M. Wicky, L. F. Milles, A. Courbet, R. J. Ragotte, J. Dauparas, E. Kinfu, S. Tipps, R. D. Kibler, M. Baek, F. DiMaio, X. Li, L. Carter, A. Kang, H. Nguyen, A. K. Bera, D. Baker
Science. Author manuscript; available in PMC 2022 Dec 6.
Published in final edited form as: Science. 2022 Oct 7; 378(6615): 56–61. Published online 2022 Sep 15. doi: 10.1126/science.add1964
PMCID:
PMC9724707
ArticlePubReaderPDF–1.7MCite
19.
Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality
Samuel J. Wattrus, Mackenzie L. Smith, Cecilia Pessoa Rodrigues, Elliott J. Hagedorn, Ji Wook Kim, Bogdan Budnik, Leonard I. Zon
Science. Author manuscript; available in PMC 2022 Sep 30.
Published in final edited form as: Science. 2022 Sep 23; 377(6613): 1413–1419. Published online 2022 Sep 22. doi: 10.1126/science.abo4837
PMCID:
PMC9524573
ArticlePubReaderPDF–1.8MCite
20.
An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif
Yan Fang, Pengcheng Sun, Xuping Xie, Mingjian Du, Fenghe Du, Jianfeng Ye, Birte K. Kalveram, Jessica A. Plante, Kenneth S. Plante, Bo Li, Xiao-chen Bai, Pei-Yong Shi, Zhijian J. Chen
Sci Immunol. 2022 Aug 4 : eabp9962. Published online 2022 Aug 4. doi: 10.1126/sciimmunol.abp9962
PMCID:
PMC9407945
ArticlePubReaderPDF–1.9MCite

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