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Select item 67321931.

Real world experience of patients with amyotrophic lateral sclerosis (ALS) in the treatment of spasticity using tetrahydrocannabinol:cannabidiol (THC:CBD)

Thomas Meyer, Andreas Funke, Christoph Münch, Dagmar Kettemann, André Maier, Bertram Walter, Annett Thomas, Susanne Spittel

BMC Neurol. 2019; 19: 222. Published online 2019 Sep 7. doi: 10.1186/s12883-019-1443-y

PMCID:: PMC6732193

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Select item 83537892.

A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?

Xiaojiao Xu, Dingding Shen, Yining Gao, Qinming Zhou, You Ni, Huanyu Meng, Hongqin Shi, Weidong Le, Shengdi Chen, Sheng Chen

Transl Neurodegener. 2021; 10: 29. Published online 2021 Aug 10. doi: 10.1186/s40035-021-00250-5

PMCID:: PMC8353789

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Select item 98810803.

Curcumin, Resveratrol and Cannabidiol as Natural Key Prototypes in Drug Design for Neuroprotective Agents

Flávia P. Dias Viegas, Vanessa Silva Gontijo, Matheus de Freitas Silva, Cindy Juliet Cristancho Ortiz, Graziella dos Reis Rosa Franco, Januário Tomás Ernesto, Caio Miranda Damasio, Isabela Marie Fernandes Silva, Thâmara Gaspar Campos, Claudio Viegas, Jr.

Curr Neuropharmacol. 2022 Jul 15; 20(7): 1297–1328. Published online 2022 Jul 15. doi: 10.2174/1570159X19666210712152532

PMCID:: PMC9881080

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Select item 64932014.

Changes in Endocannabinoid Receptors and Enzymes in the Spinal Cord of SOD1^G93A Transgenic Mice and Evaluation of a Sativex^®‐like Combination of Phytocannabinoids: Interest for Future Therapies in Amyotrophic Lateral Sclerosis

Miguel Moreno‐Martet, Francisco Espejo‐Porras, Javier Fernández‐Ruiz, Eva de Lago

CNS Neurosci Ther. 2014 Sep; 20(9): 809–815. Published online 2014 Apr 7. doi: 10.1111/cns.12262

PMCID:: PMC6493201

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Select item 80005605.

Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives

Stefano Raffaele, Marta Boccazzi, Marta Fumagalli

Cells. 2021 Mar; 10(3): 565. Published online 2021 Mar 5. doi: 10.3390/cells10030565

PMCID:: PMC8000560

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Select item 68581756.

Study protocol for a randomised, double-blind, placebo-controlled study evaluating the Efficacy of cannabis-based Medicine Extract in slowing the disease pRogression of Amyotrophic Lateral sclerosis or motor neurone Disease: the EMERALD trial

Berzenn Urbi, Simon Broadley, Richard Bedlack, Ethan Russo, Arman Sabet

BMJ Open. 2019; 9(11): e029449. Published online 2019 Nov 11. doi: 10.1136/bmjopen-2019-029449

PMCID:: PMC6858175

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Select item 69156857.

Could the Combination of Two Non-Psychotropic Cannabinoids Counteract Neuroinflammation? Effectiveness of Cannabidiol Associated with Cannabigerol

Santa Mammana, Eugenio Cavalli, Agnese Gugliandolo, Serena Silvestro, Federica Pollastro, Placido Bramanti, Emanuela Mazzon

Medicina (Kaunas) 2019 Nov; 55(11): 747. Published online 2019 Nov 18. doi: 10.3390/medicina55110747

PMCID:: PMC6915685

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Select item 83006388.

Amyotrophic Lateral Sclerosis: Molecular Mechanisms, Biomarkers, and Therapeutic Strategies

Xiaoming Yang, Yanan Ji, Wei Wang, Lilei Zhang, Zehao Chen, Miaomei Yu, Yuntian Shen, Fei Ding, Xiaosong Gu, Hualin Sun

Antioxidants (Basel) 2021 Jul; 10(7): 1012. Published online 2021 Jun 24. doi: 10.3390/antiox10071012

PMCID:: PMC8300638

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Select item 84659469.

Oxidative Stress as a Therapeutic Target in Amyotrophic Lateral Sclerosis: Opportunities and Limitations

Hee Ra Park, Eun Jin Yang

Diagnostics (Basel) 2021 Sep; 11(9): 1546. Published online 2021 Aug 26. doi: 10.3390/diagnostics11091546

PMCID:: PMC8465946

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Select item 766443710.

Molecular Targets of Cannabidiol in Experimental Models of Neurological Disease

Serena Silvestro, Giovanni Schepici, Placido Bramanti, Emanuela Mazzon

Molecules. 2020 Nov; 25(21): 5186. Published online 2020 Nov 7. doi: 10.3390/molecules25215186

PMCID:: PMC7664437

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Select item 698401611.

Novel therapeutic targets for amyotrophic lateral sclerosis

Gitika Batra, Manav Jain, Rahul Soloman Singh, Amit Raj Sharma, Ashutosh Singh, Ajay Prakash, Bikash Medhi

Indian J Pharmacol. 2019 Nov-Dec; 51(6): 418–425. Published online 2020 Jan 16. doi: 10.4103/ijp.IJP_823_19

PMCID:: PMC6984016

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Select item 651483212.

Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials

Serena Silvestro, Santa Mammana, Eugenio Cavalli, Placido Bramanti, Emanuela Mazzon

Molecules. 2019 Apr; 24(8): 1459. Published online 2019 Apr 12. doi: 10.3390/molecules24081459

PMCID:: PMC6514832

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Select item 587769213.

The Role of Macrophages in Neuroinflammatory and Neurodegenerative Pathways of Alzheimer’s Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis: Pathogenetic Cellular Effectors and Potential Therapeutic Targets

Santa Mammana, Paolo Fagone, Eugenio Cavalli, Maria Sofia Basile, Maria Cristina Petralia, Ferdinando Nicoletti, Placido Bramanti, Emanuela Mazzon

Int J Mol Sci. 2018 Mar; 19(3): 831. Published online 2018 Mar 13. doi: 10.3390/ijms19030831

PMCID:: PMC5877692

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Select item 854902314.

Inactivation of the CB₂ receptor accelerated the neuropathological deterioration in TDP‐43 transgenic mice, a model of amyotrophic lateral sclerosis

Carmen Rodríguez‐Cueto, Marta Gómez‐Almería, Laura García Toscano, Julián Romero, Cecilia J. Hillard, Eva de Lago, Javier Fernández‐Ruiz

Brain Pathol. 2021 Nov; 31(6): e12972. Published online 2021 May 13. doi: 10.1111/bpa.12972

PMCID:: PMC8549023

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Select item 726440815.

Potential Preventive Strategies for Amyotrophic Lateral Sclerosis

B. Kuraszkiewicz, H. Goszczyńska, T. Podsiadły-Marczykowska, M. Piotrkiewicz, P. Andersen, M. Gromicho, J. Grosskreutz, M. Kuźma-Kozakiewicz, S. Petri, B. Stubbendorf, K. Szacka, H. Uysal, M. de Carvalho

Front Neurosci. 2020; 14: 428. Published online 2020 May 26. doi: 10.3389/fnins.2020.00428