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Select item 67122961.

Combating Neurodegenerative Diseases with the Plant Alkaloid Berberine: Molecular Mechanisms and Therapeutic Potential

Dahua Fan, Liping Liu, Zhengzhi Wu, Meiqun Cao

Curr Neuropharmacol. 2019 Jun; 17(6): 563–579. Published online 2019 Jun. doi: 10.2174/1570159X16666180419141613

PMCID:: PMC6712296

Article PDF–921K

Select item 107790022.

Berberine Induces Mitophagy through Adenosine Monophosphate-Activated Protein Kinase and Ameliorates Mitochondrial Dysfunction in PINK1 Knockout Mouse Embryonic Fibroblasts

Jee-Hyun Um, Kang-Min Lee, Young-Yeon Kim, Da-Ye Lee, Eunmi Kim, Dong-Hyun Kim, Jeanho Yun

Int J Mol Sci. 2024 Jan; 25(1): 219. Published online 2023 Dec 22. doi: 10.3390/ijms25010219

PMCID:: PMC10779002

Article PDF–3.1M

Select item 99195063.

A Review of Fibraurea tinctoria and Its Component, Berberine, as an Antidiabetic and Antioxidant

Indah Purwaningsih, Iman Permana Maksum, Dadan Sumiarsa, Sriwidodo Sriwidodo

Molecules. 2023 Feb; 28(3): 1294. Published online 2023 Jan 29. doi: 10.3390/molecules28031294

PMCID:: PMC9919506

Article PDF–1.9M

Select item 50734384.

Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS

Cheng-Fu Chang, Yi-Chao Lee, Kuen-Haur Lee, Hui-Ching Lin, Chia-Ling Chen, Che-Kun James Shen, Chi-Chen Huang

J Biomed Sci. 2016; 23: 72. Published online 2016 Oct 21. doi: 10.1186/s12929-016-0290-z

PMCID:: PMC5073438

Article PDF–3.3M

Select item 91704585.

Effect of Berberine Hydrochloride on the Diversity of Intestinal Flora in Parkinson's Disease Patients

Jiaojiao Li, Pin Meng, Jianyu Zhang, Mingli He

Contrast Media Mol Imaging. 2022; 2022: 8381870. Published online 2022 May 30. doi: 10.1155/2022/8381870

PMCID:: PMC9170458

Article PDF–449K

Select item 79026456.

Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson’s disease by regulating gut microbiota

Yan Wang, Qian Tong, Shu-Rong Ma, Zhen-Xiong Zhao, Li-Bin Pan, Lin Cong, Pei Han, Ran Peng, Hang Yu, Yuan Lin, Tian-Le Gao, Jia-Wen Shou, Xiao-Yang Li, Xian-Feng Zhang, Zheng-Wei Zhang, Jie Fu, Bao-Ying Wen, Jin-Bo Yu, Xuetao Cao, Jian-Dong Jiang

Signal Transduct Target Ther. 2021; 6: 77. Published online 2021 Feb 24. doi: 10.1038/s41392-020-00456-5

PMCID:: PMC7902645

Article PDF–5.9M

Select item 94103607.

Research progress on the pharmacological effects of berberine targeting mitochondria

Xinyi Fang, Haoran Wu, Jiahua Wei, Runyu Miao, Yanjiao Zhang, Jiaxing Tian

Front Endocrinol (Lausanne) 2022; 13: 982145. Published online 2022 Aug 11. doi: 10.3389/fendo.2022.982145

PMCID:: PMC9410360

Article PDF–4.1M

Select item 97230738.

High-Throughput Screening Assay Identifies Berberine and Mubritinib as Neuroprotection Drugs for Spinal Cord Injury via Blood-Spinal Cord Barrier Protection

Yuki Suzuki, Shinsuke Nakagawa, Takeshi Endo, Akihito Sotome, Rufei Yuan, Tsuyoshi Asano, Satoko Otsuguro, Katsumi Maenaka, Norimasa Iwasaki, Ken Kadoya

Neurotherapeutics. 2022 Oct; 19(6): 1976–1991. Published online 2022 Sep 30. doi: 10.1007/s13311-022-01310-y

PMCID:: PMC9723073

Article PDF–8.0M

Select item 65337619.

Neuroprotective effects of berberine in animal models of Alzheimer’s disease: a systematic review of pre-clinical studies

Ning-Ning Yuan, Cui-Zan Cai, Ming-Yue Wu, Huan-Xing Su, Min Li, Jia-Hong Lu

BMC Complement Altern Med. 2019; 19: 109. Published online 2019 May 23. doi: 10.1186/s12906-019-2510-z

PMCID:: PMC6533761

Article PDF–1.0M

Select item 958323410.

Berberine Suppressed the Progression of Human Glioma Cells by Inhibiting the TGF-β1/SMAD2/3 Signaling Pathway

Yun Jin, Jiawei Zhang, Yunfeng Pan, Wangzhen Shen

Integr Cancer Ther. 2022; 21: 15347354221130303. Published online 2022 Oct 18. doi: 10.1177/15347354221130303

PMCID:: PMC9583234

Article PDF–7.4M

Select item 1061982211.

Bioassays guided isolation of berberine from Berberis lycium and its neuroprotective role in aluminium chloride induced rat model of Alzheimer’s disease combined with insilico molecular docking

Hammad Ismail, Dania Khalid, Durdana Waseem, Muhammad Umar Ijaz, Erum Dilshad, Ihsan-ul Haq, Muhammad Zeeshan Bhatti, Sadaf Anwaar, Madiha Ahmed, Samreen Saleem

PLoS One. 2023; 18(11): e0286349. Published online 2023 Nov 1. doi: 10.1371/journal.pone.0286349

PMCID:: PMC10619822

Article PDF–1.9M

Select item 856374812.

Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing spinal microglial activation

Jin-dong Zhang, Jiao Liu, Shi-wei Zhu, Yuan Fang, Ben Wang, Qiong Jia, Hui-feng Hao, John Y. Kao, Qi-hua He, Li-jin Song, Fei Liu, Bao-li Zhu, Chung Owyang, Li-ping Duan

Acta Pharmacol Sin. 2021 Nov; 42(11): 1821–1833. Published online 2021 Feb 8. doi: 10.1038/s41401-020-00601-4

PMCID:: PMC8563748

Article PDF–5.5M

Select item 1005582413.

Berberine Rescues D-Ribose-Induced Alzheimer‘s Pathology via Promoting Mitophagy

Chuanling Wang, Qian Zou, Yinshuang Pu, Zhiyou Cai, Yong Tang

Int J Mol Sci. 2023 Mar; 24(6): 5896. Published online 2023 Mar 20. doi: 10.3390/ijms24065896

PMCID:: PMC10055824

Article PDF–4.1M

Select item 671420714.

Protein kinase C is involved in the neuroprotective effect of berberine against intrastriatal injection of quinolinic acid‐induced biochemical alteration in mice

Peng Liu, Yinjie Li, Xiaoxiao Qi, Jia Xu, Danyang Liu, Xuefei Ji, Tianyan Chi, Han Liu, Libo Zou

J Cell Mol Med. 2019 Sep; 23(9): 6343–6354. Published online 2019 Jul 18. doi: 10.1111/jcmm.14522

PMCID:: PMC6714207

Article PDF–946K

Select item 916428415.

Berberine: A Promising Treatment for Neurodegenerative Diseases

Ziqian Cheng, Chenglan Kang, Songtian Che, Jingyun Su, Qihan Sun, Tongtong Ge, Yi Guo, Jiayin Lv, Zhihui Sun, Wei Yang, Bingjin Li, Xin Li, Ranji Cui

Front Pharmacol. 2022; 13: 845591. Published online 2022 May 20. doi: 10.3389/fphar.2022.845591

PMCID:: PMC9164284

Article PDF–952K

Select item 890919516.

Therapeutic Efficacies of Berberine against Neurological Disorders: An Update of Pharmacological Effects and Mechanisms

Jia-Wen Shou, Pang-Chui Shaw

Cells. 2022 Mar; 11(5): 796. Published online 2022 Feb 24. doi: 10.3390/cells11050796

PMCID:: PMC8909195

Article PDF–2.6M

Select item 582353617.

Therapeutic potential of berberine against neurodegenerative diseases

WenXiao JIANG, ShiHua LI, XiaoJiang LI

Sci China Life Sci. Author manuscript; available in PMC 2018 Feb 22.

Published in final edited form as: Sci China Life Sci. 2015 Jun; 58(6): 564–569. Published online 2015 Mar 6. doi: 10.1007/s11427-015-4829-0

PMCID:: PMC5823536

Article PDF–402K

Select item 975985918.

Berberine increases stromal production of Wnt molecules and activates Lgr5⁺ stem cells to promote epithelial restitution in experimental colitis

Zecheng Luo, Zihao Li, Zheng Liang, Lin Wang, Guanlin He, Dongdi Wang, Lei Shen, Zhengting Wang, Xiuying Ma, Funeng Geng, Haozhong Wang, Wenping Liu, Huijuan Liu, Baojie Li

BMC Biol. 2022; 20: 287. Published online 2022 Dec 17. doi: 10.1186/s12915-022-01492-z

PMCID:: PMC9759859

Article PDF–12M

Select item 960388619.

The Interplay between Gut Microbiota and Parkinson’s Disease: Implications on Diagnosis and Treatment

Angelica Varesi, Lucrezia Irene Maria Campagnoli, Foroogh Fahmideh, Elisa Pierella, Marcello Romeo, Giovanni Ricevuti, Marchesi Nicoletta, Salvatore Chirumbolo, Alessia Pascale

Int J Mol Sci. 2022 Oct; 23(20): 12289. Published online 2022 Oct 14. doi: 10.3390/ijms232012289