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Select item 66271341.

The Potential of Carnosine in Brain-Related Disorders: A Comprehensive Review of Current Evidence

Martin Schön, Aya Mousa, Michael Berk, Wern L. Chia, Jozef Ukropec, Arshad Majid, Barbara Ukropcová, Barbora de Courten

Nutrients. 2019 Jun; 11(6): 1196. Published online 2019 May 28. doi: 10.3390/nu11061196

PMCID:: PMC6627134

Abstract Article PDF–822K

Select item 75006352.

Characterisation of intracellular molecular mechanisms modulated by carnosine in porcine myoblasts under basal and oxidative stress conditions

Marie-France Palin, Jérôme Lapointe, Claude Gariépy, Danièle Beaudry, Claudia Kalbe

PLoS One. 2020; 15(9): e0239496. Published online 2020 Sep 18. doi: 10.1371/journal.pone.0239496

PMCID:: PMC7500635

Abstract Article PDF–1.6M

Select item 106702733.

The Anti-Cancer Activity of the Naturally Occurring Dipeptide Carnosine: Potential for Breast Cancer

Salvatore Maugeri, Jay Sibbitts, Anna Privitera, Vincenzo Cardaci, Lucia Di Pietro, Loredana Leggio, Nunzio Iraci, Susan M. Lunte, Giuseppe Caruso

Cells. 2023 Nov; 12(22): 2592. Published online 2023 Nov 8. doi: 10.3390/cells12222592

PMCID:: PMC10670273

Abstract Article PDF–2.4M

Select item 63564004.

Carnosine Prevents Aβ-Induced Oxidative Stress and Inflammation in Microglial Cells: A Key Role of TGF-β1

Giuseppe Caruso, Claudia G. Fresta, Nicolò Musso, Mariaconcetta Giambirtone, Margherita Grasso, Simona F. Spampinato, Sara Merlo, Filippo Drago, Giuseppe Lazzarino, Maria A. Sortino, Susan M. Lunte, Filippo Caraci

Cells. 2019 Jan; 8(1): 64. Published online 2019 Jan 17. doi: 10.3390/cells8010064

PMCID:: PMC6356400

Abstract Article PDF–2.1M

Select item 58527235.

Zinc, Carnosine, and Neurodegenerative Diseases

Masahiro Kawahara, Ken-ichiro Tanaka, Midori Kato-Negishi

Nutrients. 2018 Feb; 10(2): 147. Published online 2018 Jan 29. doi: 10.3390/nu10020147

PMCID:: PMC5852723

Abstract Article PDF–2.4M

Select item 70380636.

Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine

Claudia G. Fresta, Annamaria Fidilio, Giacomo Lazzarino, Nicolò Musso, Margherita Grasso, Sara Merlo, Angela M. Amorini, Claudio Bucolo, Barbara Tavazzi, Giuseppe Lazzarino, Susan M. Lunte, Filippo Caraci, Giuseppe Caruso

Int J Mol Sci. 2020 Feb; 21(3): 776. Published online 2020 Jan 25. doi: 10.3390/ijms21030776

PMCID:: PMC7038063

Abstract Article PDF–3.9M

Select item 101461787.

Carnosine Counteracts the Molecular Alterations Aβ Oligomers-Induced in Human Retinal Pigment Epithelial Cells

Giuseppe Caruso, Claudia G. Fresta, Annamaria Fidilio, Francesca Lazzara, Nicolò Musso, Vincenzo Cardaci, Filippo Drago, Filippo Caraci, Claudio Bucolo

Molecules. 2023 Apr; 28(8): 3324. Published online 2023 Apr 9. doi: 10.3390/molecules28083324

PMCID:: PMC10146178

Abstract Article PDF–7.1M

Select item 79126848.

Influence of Imidazole-Dipeptides on Cognitive Status and Preservation in Elders: A Narrative Review

Nobutaka Masuoka, Chenxu Lei, Haowei Li, Tatsuhiro Hisatsune

Nutrients. 2021 Feb; 13(2): 397. Published online 2021 Jan 27. doi: 10.3390/nu13020397

PMCID:: PMC7912684

Abstract Article PDF–2.1M

Select item 71772359.

Carnosine as a Possible Drug for Zinc-Induced Neurotoxicity and Vascular Dementia

Masahiro Kawahara, Yutaka Sadakane, Keiko Mizuno, Midori Kato-Negishi, Ken-ichiro Tanaka

Int J Mol Sci. 2020 Apr; 21(7): 2570. Published online 2020 Apr 7. doi: 10.3390/ijms21072570

PMCID:: PMC7177235

Abstract Article PDF–1.8M

Select item 305805510.

Effects of Dietary Supplementation of Carnosine on Mitochondrial Dysfunction, Amyloid Pathology, and Cognitive Deficits in 3xTg-AD Mice

Carlo Corona, Valerio Frazzini, Elena Silvestri, Rossano Lattanzio, Rossana La Sorda, Mauro Piantelli, Lorella M. T. Canzoniero, Domenico Ciavardelli, Enrico Rizzarelli, Stefano L. Sensi

PLoS One. 2011; 6(3): e17971. Published online 2011 Mar 15. doi: 10.1371/journal.pone.0017971

PMCID:: PMC3058055

Abstract Article PDF–1.8M

Select item 826372011.

Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response

Priyanka Joshi, Michele Perni, Ryan Limbocker, Benedetta Mannini, Sam Casford, Sean Chia, Johnny Habchi, Johnathan Labbadia, Christopher M. Dobson, Michele Vendruscolo

Commun Biol. 2021; 4: 843. Published online 2021 Jul 7. doi: 10.1038/s42003-021-02218-7

Correction in:: Commun Biol. 2021; 4: 930.

PMCID:: PMC8263720

Abstract Article PDF–9.1M

Select item 1033368412.

The therapeutic potential of carnosine: Focus on cellular and molecular mechanisms

Giuseppe Caruso, Lucia Di Pietro, Vincenzo Cardaci, Salvatore Maugeri, Filippo Caraci

Curr Res Pharmacol Drug Discov. 2023; 4: 100153. Published online 2023 Mar 7. doi: 10.1016/j.crphar.2023.100153

PMCID:: PMC10333684

Abstract Article PDF–1.0M

Select item 870613113.

Ionophore Ability of Carnosine and Its Trehalose Conjugate Assists Copper Signal in Triggering Brain-Derived Neurotrophic Factor and Vascular Endothelial Growth Factor Activation In Vitro

Irina Naletova, Valentina Greco, Sebastiano Sciuto, Francesco Attanasio, Enrico Rizzarelli

Int J Mol Sci. 2021 Dec; 22(24): 13504. Published online 2021 Dec 16. doi: 10.3390/ijms222413504

PMCID:: PMC8706131

Abstract Article PDF–4.1M

Select item 1116718414.

The protective role of carnosine against type 2 diabetes‐induced cognitive impairment

Qian Wang, Nicholas Tripodi, Zachary Valiukas, Simon M. Bell, Arshad Majid, Barbora de Courten, Vasso Apostolopoulos, Jack Feehan

Food Sci Nutr. 2024 Jun; 12(6): 3819–3833. Published online 2024 Mar 12. doi: 10.1002/fsn3.4077

PMCID:: PMC11167184

Abstract Article PDF–2.4M

Select item 370087015.

Anti-Aggregating Effect of the Naturally Occurring Dipeptide Carnosine on Aβ1-42 Fibril Formation

Alessandra Aloisi, Amilcare Barca, Alessandro Romano, Sara Guerrieri, Carlo Storelli, Rosaria Rinaldi, Tiziano Verri

PLoS One. 2013; 8(7): e68159. Published online 2013 Jul 3. doi: 10.1371/journal.pone.0068159

PMCID:: PMC3700870

Abstract Article PDF–10M

Select item 1133721016.

Quantitative Analysis of Glutathione and Carnosine Adducts with 4-Hydroxy-2-nonenal in Muscle in a hSOD1^G93A ALS Rat Model

Pablo V. M. Reis, Bianca S. Vargas, Rafael A. Rebelo, Mariana P. Massafera, Fernanda M. Prado, Hector Oreliana, Henrique V. de Oliveira, Florêncio P. Freitas, Graziella E. Ronsein, Sayuri Miyamoto, Paolo Di Mascio, Marisa H. G. Medeiros

Chem Res Toxicol. 2024 Aug 19; 37(8): 1306–1314. Published online 2024 Jul 27. doi: 10.1021/acs.chemrestox.4c00052

PMCID:: PMC11337210

Abstract Article PDF–2.8M

Select item 752473317.

Hyaluronan-carnosine conjugates inhibit Aβ aggregation and toxicity

Valentina Greco, Irina Naletova, Ikhlas M. M. Ahmed, Susanna Vaccaro, Luciano Messina, Diego La Mendola, Francesco Bellia, Sebastiano Sciuto, Cristina Satriano, Enrico Rizzarelli

Sci Rep. 2020; 10: 15998. Published online 2020 Sep 29. doi: 10.1038/s41598-020-72989-2

PMCID:: PMC7524733

Abstract Article PDF–1.5M

Select item 668305918.

Effects of Anserine/Carnosine Supplementation on Mild Cognitive Impairment with APOE4

Nobutaka Masuoka, Chitose Yoshimine, Marie Hori, Mieko Tanaka, Takashi Asada, Keiichi Abe, Tatsuhiro Hisatsune

Nutrients. 2019 Jul; 11(7): 1626. Published online 2019 Jul 17. doi: 10.3390/nu11071626

PMCID:: PMC6683059

Abstract Article PDF–2.3M

Select item 439707219.

Effects of Beta-Alanine Supplementation on Brain Homocarnosine/Carnosine Signal and Cognitive Function: An Exploratory Study

Marina Yazigi Solis, Simon Cooper, Ruth M Hobson, Guilherme G. Artioli, Maria C. Otaduy, Hamilton Roschel, Jacques Robertson, Daniel Martin, Vitor S. Painelli, Roger C. Harris, Bruno Gualano, Craig Sale

PLoS One. 2015; 10(4): e0123857. Published online 2015 Apr 14. doi: 10.1371/journal.pone.0123857