PMC

Odds ratios (ORs) and 95% CIs for factors affecting high DOAC adherence and high warfarin adherence. ORs and 95% CIs for factors affecting high DOAC adherence and high warfarin adherence. Predictors of DOAC and warfarin adherence with references are given on the left and right, respectively. DOAC adherence was assessed with proportion of days covered, while warfarin adherence was assessed with TTR. DOAC indicates direct oral anticoagulant; ED, emergency department; OAC, oral anticoagulant; and TTR, time in therapeutic range.

Adherence cut-off levels of 95% and 80% are described for women's adherence to antenatal AZT, intrapartum AZT+3TC and postpartum AZT+3TC during hospitalization, as well as for infant adherence to AZT during hospitalization. For pre-delivery AZT intake, an adherence level of ≥95% was reached by 50.0% and a level of ≥80% was reached by 65.1% of women. For intrapartum AZT+3TC, adherence of ≥95% was reached by 42.2% of women who delivered in KDH and adherence of ≥80% was reached by 59.4% of them. For postpartum AZT+3TC during hospitalization, adherence of ≥95% was reached by 37.5% and adherence of ≥80% was reached by 53.1% of hospital-delivering women. In newborns, AZT adherence during hospitalization was ≥95% in 19.0% and ≥80% in 50.8% of the infants. For sdNVP, proportions reflect self-reported correct intake of drug doses for mothers (90.5%) and staff-reported correctly dispensed drug doses for newborns (93.2%). Postpartum take-home doses were dispensed correctly to 78.4% of women and 80.8% of infants.

(A) SBP in patients with low, moderate, and high adherence with and without depression. (B) LDL-C levels in patients with low, moderate, and high adherence with and without depression.
Notes: (A) Low adherence: depression vs no depression: P=0.0007, moderate adherence: depression vs no depression: P=0.0978, high adherence: depression vs no depression: P=0.2765; depression: low vs moderate adherence: P=0.0015, moderate vs high adherence: P=0.6904, no depression: low vs moderate adherence: P<0.0001, moderate vs high adherence: P=0.8798. (B) Low adherence: depression vs no depression: P=0.9571, moderate adherence: depression vs no depression: P=0.2460, high adherence: depression vs no depression: P=0.1827; depression: low vs moderate adherence: P=0.0224, moderate vs high adherence: P=0.8997, no depression: low vs moderate adherence: P<0.0001, moderate vs high adherence: P=0.6721. MMAS-8, <6: low adherence; MMAS-8, 6–7: moderate adherence; MMAS-8, 8: high adherence.
Abbreviations: LDL-C, low-density lipoprotein cholesterol; MMAS-8, Morisky Medication Adherence Scale-8; SBP, systolic blood pressure.

□ Good adherence (percentage adherence > 95%); ■ poor adherence (percentage adherence < 95%).