Thyroid Eye Disease - PMC

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Management of Thyroid Eye Disease: A Consensus Statement by the American Thyroid Association and the European Thyroid Association

Task Force Members: Henry B. Burch, Petros Perros, Tomasz Bednarczuk, David S. Cooper, Peter J. Dolman, Angela M. Leung, Ilse Mombaerts, Mario Salvi, Marius N. Stan

Thyroid. December 2022; 32(12): 1439–1470. Published online 2022 Dec 13. doi: 10.1089/thy.2022.0251

PMCID:: PMC9807259

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Assessment of Hearing Dysfunction in Patients With Graves’ Disease and Thyroid Eye Disease Without or With Teprotumumab

Terry J Smith, Robert J Holt, Qianhong Fu, Anahita Qashqai, Naina Barretto, Elizabeth Conrad, Jason A Brant

J Clin Endocrinol Metab. 2025 Mar; 110(3): 811–819. Published online 2024 Aug 14. doi: 10.1210/clinem/dgae560

PMCID:: PMC11834702

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The Role of Fibrogenesis and Extracellular Matrix Proteins in the Pathogenesis of Graves’ Ophthalmopathy

Hsun-I Chiu, Shi-Bei Wu, Chieh-Chih Tsai

Int J Mol Sci. 2024 Mar; 25(6): 3288. Published online 2024 Mar 14. doi: 10.3390/ijms25063288

PMCID:: PMC10970309

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Teprotumumab and the Evolving Therapeutic Landscape in Thyroid Eye Disease

Andrea Lora Kossler, Raymond Douglas, Chrysoula Dosiou

J Clin Endocrinol Metab. 2022 Sep; 107(Suppl 1): S36–S46. Published online 2022 Aug 8. doi: 10.1210/clinem/dgac168

PMCID:: PMC9359446

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A Comprehensive Review of Thyroid Eye Disease Pathogenesis: From Immune Dysregulations to Novel Diagnostic and Therapeutic Approaches

Merve Kulbay, Stuti M. Tanya, Nicolas Tuli, Jade Dahoud, Andrea Dahoud, Fares Alsaleh, Bryan Arthurs, Christian El-Hadad

Int J Mol Sci. 2024 Nov; 25(21): 11628. Published online 2024 Oct 29. doi: 10.3390/ijms252111628

PMCID:: PMC11546489

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Measuring Health-Related Quality of Life in Thyroid Eye Disease

Anu Sharma, Marius N Stan, Dan B Rootman

J Clin Endocrinol Metab. 2022 Sep; 107(Suppl 1): S27–S35. Published online 2022 Aug 8. doi: 10.1210/clinem/dgac230

PMCID:: PMC9359445

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The changing landscape of thyroid eye disease: current clinical advances and future outlook

Malik Moledina, Erika M. Damato, Vickie Lee

Eye (Lond) 2024 Jun; 38(8): 1425–1437. Published online 2024 Feb 19. doi: 10.1038/s41433-024-02967-9

PMCID:: PMC11126416

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Future Projections in Thyroid Eye Disease

Giuseppe Barbesino, Mario Salvi, Suzanne K Freitag

J Clin Endocrinol Metab. 2022 Sep; 107(Suppl 1): S47–S56. Published online 2022 Aug 8. doi: 10.1210/clinem/dgac252

PMCID:: PMC9359449

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Current concepts regarding Graves’ orbitopathy

Luigi Bartalena, Maria Laura Tanda

J Intern Med. 2022 Nov; 292(5): 692–716. Published online 2022 Jun 1. doi: 10.1111/joim.13524

PMCID:: PMC9796560

Article PDF–886K

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Computed tomography and magnetic resonance imaging approaches to Graves’ ophthalmopathy: a narrative review

Rafael Luccas, Cinthia Minatel Riguetto, Monica Alves, Denise Engelbrecht Zantut-Wittmann, Fabiano Reis

Front Endocrinol (Lausanne) 2023; 14: 1277961. Published online 2024 Jan 8. doi: 10.3389/fendo.2023.1277961

PMCID:: PMC10801040

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Recent advances in graves ophthalmopathy medical therapy: a comprehensive literature review

Xueting Li, Senmao Li, Wanlin Fan, Alexander C. Rokohl, Sitong Ju, Xiaojun Ju, Yongwei Guo, Ludwig M. Heindl

Int Ophthalmol. 2023; 43(4): 1437–1449. Published online 2022 Oct 22. doi: 10.1007/s10792-022-02537-6

PMCID:: PMC10113320

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Management of thyroid eye disease: a Consensus Statement by the American Thyroid Association and the European Thyroid Association

Henry B Burch, Petros Perros, Tomasz Bednarczuk, David S Cooper, Peter J Dolman, Angela M Leung, Ilse Mombaerts, Mario Salvi, Marius N Stan

Eur Thyroid J. 2022 Dec 1; 11(6): e220189. Published online 2022 Dec 8. doi: 10.1530/ETJ-22-0189

PMCID:: PMC9727317

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Cytokines as Targets of Novel Therapies for Graves’ Ophthalmopathy

Poupak Fallahi, Silvia Martina Ferrari, Giusy Elia, Francesca Ragusa, Sabrina Rosaria Paparo, Armando Patrizio, Stefania Camastra, Mario Miccoli, Gabriella Cavallini, Salvatore Benvenga, Alessandro Antonelli

Front Endocrinol (Lausanne) 2021; 12: 654473. Published online 2021 Apr 16. doi: 10.3389/fendo.2021.654473

PMCID:: PMC8085526

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2021 Update on Thyroid-Associated Ophthalmopathy

Emily J. Neag, Terry J. Smith

J Endocrinol Invest. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: J Endocrinol Invest. 2022 Feb; 45(2): 235–259. Published online 2021 Aug 20. doi: 10.1007/s40618-021-01663-9

PMCID:: PMC9455782

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Overview of Graves Ophthalmopathy Literature From 1999 to 2019: Bibliometric Analysis

Jiamin Cao, Nuo Wang, Shiying Hou, Xin Qi, Yu Chen, Wei Xiong

Interact J Med Res. 2021 Jul-Sep; 10(3): e24831. Published online 2021 Sep 28. doi: 10.2196/24831

PMCID:: PMC8512195

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Understanding Pathogenesis Intersects With Effective Treatment for Thyroid Eye Disease

Terry J Smith

J Clin Endocrinol Metab. 2022 Sep; 107(Suppl 1): S13–S26. Published online 2022 Aug 8. doi: 10.1210/clinem/dgac328

Correction in:: J Clin Endocrinol Metab. 2023 Mar; 108(3): e46.

PMCID:: PMC9359447

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Select item 1015116117.

Thyrotropin Receptor Autoantibody Assessment in Thyroid Eye Disease: Does the Assay Type Matter?

Malik Moledina, Jonathan Roos, Rachna Murthy

Korean J Ophthalmol. 2023 Apr; 37(2): 147–156. Published online 2023 Apr 5. doi: 10.3341/kjo.2022.0131

PMCID:: PMC10151161

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Thyroid eye disease or Graves’ orbitopathy: What name to use, and why it matters

Lilly H. Wagner, Elizabeth A. Bradley, Andrea A. Tooley, Yanhan Ren, Kharisa N. Rachmasari, Marius N. Stan

Front Endocrinol (Lausanne) 2022; 13: 1083886. Published online 2022 Nov 28. doi: 10.3389/fendo.2022.1083886

PMCID:: PMC9742525

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Graves’ Ophthalmopathy

Rebecca S. Bahn

N Engl J Med. Author manuscript; available in PMC 2014 Jan 25.

Published in final edited form as: N Engl J Med. 2010 Feb 25; 362(8): 726–738. doi: 10.1056/NEJMra0905750

PMCID:: PMC3902010

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Immune checkpoints: new insights into the pathogenesis of thyroid eye disease

Xingyi Shu, Yuchao Shao, Yuqing Chen, Chengcheng Zeng, Xiao Huang, Ruili Wei

Front Immunol. 2024; 15: 1392956. Published online 2024 May 16. doi: 10.3389/fimmu.2024.1392956

PMCID:: PMC11137266

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PMC Images search for Thyroid Eye Disease

Figure 2. Thyroid Status at Time of Thyroid Eye Disease Diagnosis in Denmark (2000-2018)

The majority of the patients diagnosed with thyroid eye disease were hyperthyroid. The thyroid status proportions did not change over the time studied in either men or women.

Nationwide Incidence of Thyroid Eye Disease and Cumulative Incidence of Strabismus and Surgical Interventions in Denmark

JAMA Ophthalmol. 2022 Jul;140(7):667-673.
Figure 2Display of a normal orbit and thyroid eye disease orbits on ITK-SNAP, demonstrating soft tissue enlargement in thyroid eye disease

Extraocular Muscle Enlargement in Thyroid Eye Disease Using Volumetric Analysis

Cureus. 2024 Jul;16(7):e63843.
FIGURE 11

Box-and-whiskers plot for the presence (“y”) or absence (“n”) of thyroid eye disease. Outliers (±2 SD limits, indicated by the whiskers) are noted with greater frequency in the thyroid eye disease group than those without thyroid eye disease.

The Role of Thyroid Eye Disease and Other Factors in the Overcorrection of Hypotropia Following Unilateral Adjustable Suture Recession of the Inferior Rectus (An American Ophthalmological Society Thesis)

Trans Am Ophthalmol Soc. 2011 Dec;109:168-200.
Figure 2

Severe exophthalmos in thyroid eye disease.

Medical management of thyroid eye disease

Saudi J Ophthalmol. 2011 Jan;25(1):3-13.