Rufinamide OR 106308-44-5 [rn] - PMC

Lucille A. Lumley, Donna A. Nguyen, Marcio de Araujo Furtado, Jerome Niquet, Emily O. Linz, Caroline R. Schultz, Michael F. Stone, Claude G. Wasterlain

J Pharmacol Exp Ther. 2024 Feb; 388(2): 347–357. Published online 2024 Feb. doi: 10.1124/jpet.123.001789

PMCID:: PMC10801783

Article PDF–3.1M

Select item 74797035.

Rufinamide

Santiago Arroyo

Neurotherapeutics. 2007 Jan; 4(1): 155–162. doi: 10.1016/j.nurt.2006.11.006

PMCID:: PMC7479703

Article PDF–326K

Select item 42566166.

Exposure to rufinamide and risks of CNS adverse events in drug-resistant epilepsy: a meta-analysis of randomized, placebo-controlled trials

Abdulaziz M S Alsaad, Gideon Koren

Br J Clin Pharmacol. 2014 Dec; 78(6): 1264–1271. Published online 2014 Nov 20. doi: 10.1111/bcp.12479

PMCID:: PMC4256616

Article PDF–1.0M

Select item 96976147.

Rufinamide, a Triazole-Derived Antiepileptic Drug, Stimulates Ca²⁺-Activated K⁺ Currents While Inhibiting Voltage-Gated Na⁺ Currents

Ming-Chi Lai, Sheng-Nan Wu, Chin-Wei Huang

Int J Mol Sci. 2022 Nov; 23(22): 13677. Published online 2022 Nov 8. doi: 10.3390/ijms232213677

PMCID:: PMC9697614

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Drug-induced QT-interval shortening following antiepileptic treatment with oral rufinamide

Rainer Schimpf, Christian Veltmann, Theano Papavassiliu, Boris Rudic, Turgay Göksu, Jürgen Kuschyk, Christian Wolpert, Charles Antzelevitch, Alois Ebner, Martin Borggrefe, Christian Brandt

Heart Rhythm. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Heart Rhythm. 2012 May; 9(5): 776–781. Published online 2012 Jan 11. doi: 10.1016/j.hrthm.2012.01.006

PMCID:: PMC3482382

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Select item 96936099.

Mechanochemical Approach towards Multi-Functionalized 1,2,3-Triazoles and Anti-Seizure Drug Rufinamide Analogs Using Copper Beads

Dhananjay Bhattacherjee, Igor S. Kovalev, Dmitry S. Kopchuk, Matiur Rahman, Sougata Santra, Grigory V. Zyryanov, Pralay Das, Rituraj Purohit, Vladimir L. Rusinov, Oleg N. Chupakhin

Molecules. 2022 Nov; 27(22): 7784. Published online 2022 Nov 11. doi: 10.3390/molecules27227784

PMCID:: PMC9693609

Article PDF–2.6M

Select item 402795310.

Na_v1.1 Modulation by a Novel Triazole Compound Attenuates Epileptic Seizures in Rodents

John Gilchrist, Stacey Dutton, Marcelo Diaz-Bustamante, Annie McPherson, Nicolas Olivares, Jeet Kalia, Andrew Escayg, Frank Bosmans

ACS Chem Biol. 2014 May 16; 9(5): 1204–1212. Published online 2014 Mar 17. doi: 10.1021/cb500108p

PMCID:: PMC4027953

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Retention rates of rufinamide in pediatric epilepsy patients with and without Lennox–Gastaut Syndrome

Sudha Kilaru Kessler, Ann McCarthy, Avital Cnaan, Dennis J. Dlugos

Epilepsy Res. Author manuscript; available in PMC 2016 Mar 23.

Published in final edited form as: Epilepsy Res. 2015 May; 112: 18–26. Published online 2015 Feb 14. doi: 10.1016/j.eplepsyres.2015.02.003

PMCID:: PMC4805421

Article PDF–706K

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Adjunctive Rufinamide in Children with Lennox-Gastaut Syndrome: A Literature Review

Ganna Balagura, Antonella Riva, Francesca Marchese, Alberto Verrotti, Pasquale Striano

Neuropsychiatr Dis Treat. 2020; 16: 369–379. Published online 2020 Feb 5. doi: 10.2147/NDT.S185774

PMCID:: PMC7008198

Article PDF–580K

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Novel seizure outcomes in patients with Lennox‐Gastaut syndrome: Post hoc analysis of seizure‐free days in rufinamide Study 303

Stéphane Auvin, Betsy Williams, Rob McMurray, Dinesh Kumar, Carlos Perdomo, Manoj Malhotra

Epilepsia Open. 2019 Jun; 4(2): 275–280. Published online 2019 Mar 13. doi: 10.1002/epi4.12314

PMCID:: PMC6546073

Article PDF–191K

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Multistep Solvent-Free 3 m² Footprint Pilot Miniplant for the Synthesis of Annual Half-Ton Rufinamide Precursor

Marc Escribà-Gelonch, Gerardo Antonio de Leon Izeppi, Dirk Kirschneck, Volker Hessel

ACS Sustain Chem Eng. 2019 Oct 21; 7(20): 17237–17251. Published online 2019 Sep 26. doi: 10.1021/acssuschemeng.9b03931

PMCID:: PMC6812013

Article PDF–11M

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Treatment of Adults with Lennox–Gastaut Syndrome: Further Analysis of Efficacy and Safety/Tolerability of Rufinamide

Rob McMurray, Pasquale Striano

Neurol Ther. 2016 Jun; 5(1): 35–43. Published online 2016 Feb 10. doi: 10.1007/s40120-016-0041-9

PMCID:: PMC4919131

Article PDF–590K

Select item 265453116.

Role of rufinamide in the management of Lennox-Gastaut syndrome (childhood epileptic encephalopathy)

Gerhard Kluger, Bettina Bauer

Neuropsychiatr Dis Treat. 2007 Feb; 3(1): 3–11. doi: 10.2147/nedt.2007.3.1.3

PMCID:: PMC2654531

Article PDF–155K

Select item 295174717.

Treating Lennox–Gastaut syndrome in epileptic pediatric patients with third-generation rufinamide

Jessica Gresham, Lea S Eiland, Allison M Chung

Neuropsychiatr Dis Treat. 2010; 6: 639–645. Published online 2010 Oct 5. doi: 10.2147/NDT.S6465

PMCID:: PMC2951747

Article PDF–162K

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Update on rufinamide in childhood epilepsy

Giangennaro Coppola

Neuropsychiatr Dis Treat. 2011; 7: 399–407. Published online 2011 Jul 5. doi: 10.2147/NDT.S13910

PMCID:: PMC3140292

Article PDF–169K

Select item 842436319.

Liquid chromatographic methods for determination of the new antiepileptic drugs stiripentol, retigabine, rufinamide and perampanel: A comprehensive and critical review

Sara Meirinho, Márcio Rodrigues, Ana Fortuna, Amílcar Falcão, Gilberto Alves

J Pharm Anal. 2021 Aug; 11(4): 405–421. Published online 2020 Nov 28. doi: 10.1016/j.jpha.2020.11.005

PMCID:: PMC8424363

Article PDF–630K

Select item 269753720.

Onset of action and seizure control in Lennox-Gaustaut syndrome: focus on rufinamide

Russell P Saneto, Gail D Anderson

Ther Clin Risk Manag. 2009; 5: 271–280. Published online 2009 May 4. doi: 10.2147/tcrm.s4282

PMCID:: PMC2697537

Article PDF–1.8M

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