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Select item 91594471.

Small molecules released from islets of Langerhans determined by liquid chromatography – mass spectrometry

Emmanuel O. Ogunkunle, Matthew J. Donohue, Daniel J. Steyer, Damilola I. Adeoye, Wesley J. Eaton, Michael G. Roper

Anal Methods. 2022 Jun 1; 14(21): 2100–2107. Published online 2022 May 14. doi: 10.1039/d2ay00402j

PMCID:: PMC9159447

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Select item 83620702.

Inherent Ethyl Acetate Selectivity in a Trianglimine Molecular Solid

Donglin He, Chengxi Zhao, Dr. Linjiang Chen, Dr. Marc A. Little, Dr. Samantha Y. Chong, Rob Clowes, Katherine McKie, Mark G. Roper, Graeme M. Day, Dr. Ming Liu, Prof. Andrew I. Cooper

Chemistry. 2021 Jul 21; 27(41): 10589–10594. Published online 2021 May 27. doi: 10.1002/chem.202101510

PMCID:: PMC8362070

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Select item 73044393.

Profiling Glucose-Stimulated and M3 Receptor-Activated Insulin Secretion Dynamics from Islets of Langerhans Using an Extended-Lifetime Fluorescence Dye

Joel E. Adablah, Yao Wang, Matthew Donohue, Michael G. Roper

Anal Chem. 2020 Jun 16; 92(12): 8464–8471. Published online 2020 May 20. doi: 10.1021/acs.analchem.0c01226

PMCID:: PMC7304439

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Select item 68142494.

Synchronized Stimulation and Continuous Insulin Sensing in a Microfluidic Human Islet on a Chip Designed for Scalable Manufacturing

Aaron L. Glieberman, Benjamin D. Pope, John F. Zimmerman, Qihan Liu, John P. Ferrier, Jr., Jennifer H. R. Kenty, Adrian M. Schrell, Nikita Mukhitov, Kevin L. Shores, Adrian Buganza Tepole, Douglas A. Melton, Michael G. Roper, Kevin Kit Parker

Lab Chip. Author manuscript; available in PMC 2020 Sep 10.

Published in final edited form as: Lab Chip. 2019 Sep 10; 19(18): 2993–3010. doi: 10.1039/c9lc00253g

PMCID:: PMC6814249

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Select item 64724935.

Online Measurement of Glucose Consumption from HepG2 Cells Using an Integrated Bioreactor and Enzymatic Assay

Anna G. Adams, Radha Krishna Murthy Bulusu, Nikita Mukhitov, Jose L. Mendoza-Cortes, Michael G. Roper

Anal Chem. 2019 Apr 16; 91(8): 5184–5190. Published online 2019 Mar 19. doi: 10.1021/acs.analchem.8b05798

PMCID:: PMC6472493

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Select item 65022596.

Chiral micellar electrokinetic chromatographic separation for determination of L- and D-primary amines released from murine islets of Langerhans

Kimberly Evans, Xue Wang, Michael G. Roper

Anal Methods. Author manuscript; available in PMC 2020 Mar 7.

Published in final edited form as: Anal Methods. 2019 Mar 7; 11(9): 1276–1283. Published online 2019 Feb 18. doi: 10.1039/c8ay02471e

PMCID:: PMC6502259

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Select item 63649407.

Synchronization of pancreatic islets by periodic or non-periodic muscarinic agonist pulse trains

Joel E. Adablah, Ryan Vinson, Michael G. Roper, Richard Bertram

PLoS One. 2019; 14(2): e0211832. Published online 2019 Feb 6. doi: 10.1371/journal.pone.0211832

PMCID:: PMC6364940

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Select item 61337618.

Microfluidic-enabled quantitative measurements of insulin release dynamics from single islets of Langerhans in response to 5-palmitic acid hydroxy stearic acid

Basel Bandak, Lian Yi, Michael G. Roper

Lab Chip. Author manuscript; available in PMC 2019 Sep 11.

Published in final edited form as: Lab Chip. 2018 Sep 11; 18(18): 2873–2882. doi: 10.1039/c8lc00624e

PMCID:: PMC6133761

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Select item 54073189.

Online fluorescence anisotropy immunoassay for monitoring insulin secretion from islets of Langerhans

Adrian M. Schrell, Nikita Mukhitov, Lian Yi, Joel E. Adablah, Joshua Menezes, Michael G. Roper

Anal Methods. Author manuscript; available in PMC 2018 Jan 7.

Published in final edited form as: Anal Methods. 2017 Jan 7; 9(1): 38–45. Published online 2016 Oct 28. doi: 10.1039/C6AY02899C

PMCID:: PMC5407318

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Select item 508288510.

Glucose Oscillations Can Activate an Endogenous Oscillator in Pancreatic Islets

Joseph P. McKenna, Raghuram Dhumpa, Nikita Mukhitov, Michael G. Roper, Richard Bertram

PLoS Comput Biol. 2016 Oct; 12(10): e1005143. Published online 2016 Oct 27. doi: 10.1371/journal.pcbi.1005143

PMCID:: PMC5082885

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Select item 499154311.

Multiplexing fluorescence anisotropy using frequency encoding

Adrian M. Schrell, Nikita Mukhitov, Michael G. Roper

Anal Chem. Author manuscript; available in PMC 2017 Aug 16.

Published in final edited form as: Anal Chem. 2016 Aug 16; 88(16): 7910–7915. Published online 2016 Aug 2. doi: 10.1021/acs.analchem.6b02131

PMCID:: PMC4991543

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Select item 455822312.

Measurement of the Entrainment Window of Islets of Langerhans by Microfluidic Delivery of a Chirped Glucose Waveform

Raghuram Dhumpa, Tuan M. Truong, Xue Wang, Michael G. Roper

Integr Biol (Camb) Author manuscript; available in PMC 2016 Sep 1.

Published in final edited form as: Integr Biol (Camb). 2015 Sep 1; 7(9): 1061–1067. Published online 2015 Jul 27. doi: 10.1039/c5ib00156k

PMCID:: PMC4558223

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Select item 443343213.

Micellar electrokinetic chromatography method for measuring amino acid secretions from islets of Langerhans

Xue Wang, Lian Yi, Christelle Guillo, Michael G. Roper

Electrophoresis. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Electrophoresis. 2015 May; 36(0): 1172–1178. Published online 2015 Apr 21. doi: 10.1002/elps.201400569

PMCID:: PMC4433432

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Select item 405228014.

Negative Feedback Synchronizes Islets of Langerhans

Raghuram Dhumpa, Tuan M. Truong, Xue Wang, Richard Bertram, Michael G. Roper

Biophys J. 2014 May 20; 106(10): 2275–2282. doi: 10.1016/j.bpj.2014.04.015

PMCID:: PMC4052280

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Select item 377015115.

Simultaneous monitoring of insulin and islet amyloid polypeptide secretion from islets of Langerhans on a microfluidic device

Anna R. Lomasney, Lian Yi, Michael G. Roper

Anal Chem. Author manuscript; available in PMC 2014 Aug 20.

Published in final edited form as: Anal Chem. 2013 Aug 20; 85(16): 7919–7925. Published online 2013 Jul 30. doi: 10.1021/ac401625g

PMCID:: PMC3770151

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Select item 382811916.

Maintaining Stimulant Waveforms in Large Volume Microfluidic Cell Chambers

Xinyu Zhang, Raghuram Dhumpa, Michael G. Roper

Microfluid Nanofluidics. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Microfluid Nanofluidics. 2013 Jul 1; 15(1): 10.1007/s10404-012-1129-x. Published online 2012 Dec 28. doi: 10.1007/s10404-012-1129-x

PMCID:: PMC3828119

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Select item 342803517.

Temporal gradients in microfluidic systems to probe cellular dynamics: A review

Raghuram Dhumpa, Michael G. Roper

Anal Chim Acta. Author manuscript; available in PMC 2013 Sep 19.

Published in final edited form as: Anal Chim Acta. 2012 Sep 19; 743C: 9–18. Published online 2012 Jul 14. doi: 10.1016/j.aca.2012.07.006

PMCID:: PMC3428035

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Select item 331034418.

Quantitative polymerase chain reaction using infrared heating on a microfluidic chip

Yingjie Yu, Bowei Li, Christopher A. Baker, Xinyu Zhang, Michael G. Roper

Anal Chem. Author manuscript; available in PMC 2013 Mar 20.

Published in final edited form as: Anal Chem. 2012 Mar 20; 84(6): 2825–2829. Published online 2012 Mar 2. doi: 10.1021/ac203307h

PMCID:: PMC3310344

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Select item 292165119.

Microfluidic System for Generation of Sinusoidal Glucose Waveforms for Entrainment of Islets of Langerhans

Xinyu Zhang, Alix Grimley, Richard Bertram, Michael G. Roper

Anal Chem. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: Anal Chem. 2010 Aug 1; 82(15): 6704–6711. doi: 10.1021/ac101461x

PMCID:: PMC2921651

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Select item 292346020.

A Continuous-Flow, Microfluidic Fraction Collection Device

Christopher Baker, Michael G. Roper

J Chromatogr A. Author manuscript; available in PMC 2011 Jul 9.

Published in final edited form as: J Chromatogr A. 2010 Jul 9; 1217(28): 4743–4748. doi: 10.1016/j.chroma.2010.05.023

PMCID:: PMC2923460

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PMC Images search for Roper MG

Röper on annual family holiday in Brittany
PHOTO COURTESY OF KATJA RÖPER

Katja Röper: Deciphering tissue origami

J Cell Biol. 2016 Oct 24;215(2):140-141.
Katja Röper
PHOTO COURTESY OF KATJA RÖPER

Katja Röper: Deciphering tissue origami

J Cell Biol. 2016 Oct 24;215(2):140-141.
A salivary gland placode during early tissue bending in a confocal image (left panel) labeled for Crumbs (red), E-cadherin (blue), and Scribble (green), as well as a segmented placode showing 3D cell shapes (right panel).
IMAGE COURTESY OF KATJA RÖPER

Katja Röper: Deciphering tissue origami

J Cell Biol. 2016 Oct 24;215(2):140-141.
Figure 1

Traditional modeling of external hold-up volumes by a linear PFR and CSTR sequence Roper and Lightfoot model (Roper and Lightfoot, ).

Zonal Rate Model for Axial and Radial Flow Membrane Chromatography. Part I: Knowledge Transfer Across Operating Conditions and Scales

Biotechnol Bioeng. 2013 Apr;110(4):1129-1141.