Robert J Wilkinson[Author] - PMC

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Select item 79969721.

TBDBT: A TB DataBase Template for collection of harmonized TB clinical research data in REDCap, facilitating data standardisation for inter-study comparison and meta-analyses

Taryn Allie, Amanda Jackson, Jon Ambler, Katherine Johnston, Elsa Du Bruyn, Charlotte Schultz, Linda Boloko, Sean Wasserman, Angharad Davis, Graeme Meintjes, Robert J. Wilkinson, Nicki Tiffin

PLoS One. 2021; 16(3): e0249165. Published online 2021 Mar 26. doi: 10.1371/journal.pone.0249165

PMCID:: PMC7996972

Article PubReader PDF–825K Cite

Select item 79389112.

Diagnostic Accuracy of the INSHI Consensus Case Definition for the Diagnosis of Paradoxical Tuberculosis-IRIS

Cari Stek, Jozefien Buyze, Joris Menten, Charlotte Schutz, Friedrich Thienemann, Lisette Blumenthal, Gary Maartens, Tom Boyles, Robert J. Wilkinson, Graeme Meintjes, Lutgarde Lynen

J Acquir Immune Defic Syndr. 2021 Apr 15; 86(5): 587–592. Published online 2020 Dec 17. doi: 10.1097/QAI.0000000000002606

PMCID:: PMC7938911

Article PubReader PDF–166K Cite

Select item 79730933.

Antiretroviral Treatment-Induced Decrease in Immune Activation Contributes to Reduced Susceptibility to Tuberculosis in HIV-1/Mtb Co-infected Persons

Katalin A. Wilkinson, Deborah Schneider-Luftman, Rachel Lai, Christopher Barrington, Nishtha Jhilmeet, David M. Lowe, Gavin Kelly, Robert J. Wilkinson

Front Immunol. 2021; 12: 645446. Published online 2021 Mar 5. doi: 10.3389/fimmu.2021.645446

PMCID:: PMC7973093

Article PubReader PDF–963K Cite

Select item 79476594.

Evaluation of Host Serum Protein Biomarkers of Tuberculosis in sub-Saharan Africa

Thomas C. Morris, Clive J. Hoggart, Novel N. Chegou, Martin Kidd, Tolu Oni, Rene Goliath, Katalin A. Wilkinson, Hazel M. Dockrell, Lifted Sichali, Louis Banda, Amelia C. Crampin, Neil French, Gerhard Walzl, Michael Levin, Robert J. Wilkinson, Melissa S. Hamilton

Front Immunol. 2021; 12: 639174. Published online 2021 Feb 25. doi: 10.3389/fimmu.2021.639174

PMCID:: PMC7947659

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Select item 77391175.

Recent Developments in Tuberculous Meningitis Pathogenesis and Diagnostics

Fiona V Cresswell, Angharad G. Davis, Kusum Sharma, Robindra Basu Roy, Ahmad Rizal Ganiem, Enock Kagimu, Regan Solomons, Robert J. Wilkinson, Nathan C Bahr, Nguyen Thuy Thuong Thuong, Tuberculous Meningitis International Research Consortium

Version 3. Wellcome Open Res. 2019; 4: 164. Published online 2021 Jan 28. doi: 10.12688/wellcomeopenres.15506.3

PMCID:: PMC7739117

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Select item 76481246.

An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South Africa

Elouise E. Kroon, Craig J. Kinnear, Marianna Orlova, Stephanie Fischinger, Sally Shin, Sihaam Boolay, Gerhard Walzl, Ashley Jacobs, Robert J. Wilkinson, Galit Alter, Erwin Schurr, Eileen G. Hoal, Marlo Möller

EBioMedicine. 2020 Nov; 61: 103053. Published online 2020 Oct 7. doi: 10.1016/j.ebiom.2020.103053

PMCID:: PMC7648124

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Select item 76549147.

Rapid, simplified whole blood-based multiparameter assay to quantify and phenotype SARS-CoV-2 specific T cells

Catherine Riou, Georgia Schäfer, Elsa du Bruyn, Rene T. Goliath, Cari Stek, Huihui Mou, Deli Hung, Katalin A. Wilkinson, Robert J. Wilkinson

Version 1. medRxiv. Preprint. 2020 Nov 3. doi: 10.1101/2020.10.30.20223099

PMCID:: PMC7654914

Abstract Article Cite

Select item 75208058.

Disease extent and anti‐tubercular treatment response correlates with Mycobacterium tuberculosis‐specific CD4 T‐cell phenotype regardless of HIV‐1 status

Catherine Riou, Elsa Du Bruyn, Sheena Ruzive, Rene T Goliath, Cecilia S Lindestam Arlehamn, Alessandro Sette, Alan Sher, Daniel L Barber, Robert J Wilkinson

Clin Transl Immunology. 2020; 9(9): e1176. Published online 2020 Sep 28. doi: 10.1002/cti2.1176

PMCID:: PMC7520805

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Select item 75085929.

HIV Coinfection Is Associated with Low-Fitness rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis

Chloé Loiseau, Daniela Brites, Miriam Reinhard, Kathrin Zürcher, Sonia Borrell, Marie Ballif, Lukas Fenner, Helen Cox, Liliana K. Rutaihwa, Robert J. Wilkinson, Marcel Yotebieng, E. Jane Carter, Alash'le Abimiku, Olivier Marcy, Eduardo Gotuzzo, Anchalee Avihingsanon, Nicola Zetola, Basra Doulla, Erik C. Böttger, Matthias Egger, Sebastien Gagneux

Antimicrob Agents Chemother. 2020 Oct; 64(10): e00782-20. Prepublished online 2020 Jul 27. Published online 2020 Sep 21. doi: 10.1128/AAC.00782-20

PMCID:: PMC7508592

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Select item 715677310.

Invariant Natural Killer T-cell Dynamics in Human Immunodeficiency Virus–associated Tuberculosis

Naomi F Walker, Charles Opondo, Graeme Meintjes, Nishtha Jhilmeet, Jon S Friedland, Paul T Elkington, Robert J Wilkinson, Katalin A Wilkinson

Clin Infect Dis. 2020 May 1; 70(9): 1865–1874. Published online 2019 Jun 12. doi: 10.1093/cid/ciz501

PMCID:: PMC7156773

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Select item 713258811.

The Mtb-HIV syndemic interaction: why treating M. tuberculosis infection may be crucial for HIV-1 eradication

Robyn Waters, Mthawelanga Ndengane, Melissa-Rose Abrahams, Collin R Diedrich, Robert J Wilkinson, Anna K Coussens

Future Virol. 2020 Feb; 15(2): 101–125. Published online 2020 Mar 24. doi: 10.2217/fvl-2019-0069

PMCID:: PMC7132588

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Select item 706647012.

The effect of HIV-associated tuberculosis, tuberculosis-IRIS and prednisone on lung function

Cari Stek, Brian Allwood, Elsa Du Bruyn, Jozefien Buyze, Charlotte Schutz, Friedrich Thienemann, Adele Lombard, Robert J. Wilkinson, Graeme Meintjes, Lutgarde Lynen

Eur Respir J. 2020 Mar; 55(3): 1901692. Published online 2020 Mar 12. doi: 10.1183/13993003.01692-2019

PMCID:: PMC7066470

Article PubReader PDF–556K Cite

Select item 705838313.

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α

Liku B Tezera, Magdalena K Bielecka, Paul Ogongo, Naomi F Walker, Matthew Ellis, Diana J Garay-Baquero, Kristian Thomas, Michaela T Reichmann, David A Johnston, Katalin Andrea Wilkinson, Mohamed Ahmed, Sanjay Jogai, Suwan N Jayasinghe, Robert J Wilkinson, Salah Mansour, Gareth J Thomas, Christian H Ottensmeier, Alasdair Leslie, Paul T Elkington

eLife. 2020; 9: e52668. Published online 2020 Feb 24. doi: 10.7554/eLife.52668

PMCID:: PMC7058383

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Select item 676336214.

KEY CONSIDERATIONS IN THE PHARMACOTHERAPY OF TUBERCULOUS MENINGITIS

Sean Wasserman, Angharad Davis, Robert J Wilkinson, Graeme Meintjes

Expert Opin Pharmacother. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Expert Opin Pharmacother. 2019 Oct; 20(15): 1791–1795. Published online 2019 Jul 15. doi: 10.1080/14656566.2019.1638912

PMCID:: PMC6763362

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Select item 661156815.

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study

Charlotte Schutz, David Barr, Bruno B. Andrade, Muki Shey, Amy Ward, Saskia Janssen, Rosie Burton, Katalin A. Wilkinson, Bianca Sossen, Kiyoshi F. Fukutani, Mark Nicol, Gary Maartens, Robert J. Wilkinson, Graeme Meintjes

PLoS Med. 2019 Jul; 16(7): e1002840. Published online 2019 Jul 5. doi: 10.1371/journal.pmed.1002840

PMCID:: PMC6611568

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Select item 647144516.

Matrix Metalloproteinases in Pulmonary and Central Nervous System Tuberculosis—A Review

Ursula K. Rohlwink, Naomi F. Walker, Alvaro A. Ordonez, Yifan J. Li, Elizabeth W. Tucker, Paul T. Elkington, Robert J. Wilkinson, Katalin A. Wilkinson

Int J Mol Sci. 2019 Mar; 20(6): 1350. Published online 2019 Mar 18. doi: 10.3390/ijms20061350

PMCID:: PMC6471445

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Select item 635537017.

Projected Population-Wide Impact of Antiretroviral Therapy-Linked Isoniazid Preventive Therapy in a High-Burden Setting

Emily A. KENDALL, Andrew S. AZMAN, Gary MAARTENS, Andrew BOULLE, Robert J. WILKINSON, David W. DOWDY, Molebogeng X. RANGAKA

AIDS. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: AIDS. 2019 Mar 1; 33(3): 525–536. doi: 10.1097/QAD.0000000000002053

PMCID:: PMC6355370

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Select item 648238218.

Drug susceptibility testing and mortality in patients treated for tuberculosis in high-burden countries: a multi-centre cohort study

Kathrin Zürcher, Marie Ballif, Lukas Fenner, Sonia Borrell, Peter M. Keller, Joachim Gnokoro, Olivier Marcy, Marcel Yotebieng, Lameck Diero, E. Jane Carter, Neesha Rockwood, Robert J. Wilkinson, Helen Cox, Nicholas Ezati, Alash’le G. Abimiku, Jimena Collantes, Anchalee Avihingsanon, Kamon Kawkitinarong, Miriam Reinhard, Rico Hömke, Robin Huebner, Sebastien Gagneux, Erik C. Böttger, Matthias Egger

Lancet Infect Dis. Author manuscript; available in PMC 2019 Apr 25.

Published in final edited form as: Lancet Infect Dis. 2019 Mar; 19(3): 298–307. Published online 2019 Feb 8. doi: 10.1016/S1473-3099(18)30673-X