Robert J Wilkinson[Author] - PMC

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Select item 69259131.

Expression of USP18 and IL2RA Is Increased in Individuals Receiving Latent Tuberculosis Treatment with Isoniazid

Eleane de Oyarzabal, Lourdes García-García, Claudia Rangel-Escareño, Leticia Ferreyra-Reyes, Lorena Orozco, María Teresa Herrera, Claudia Carranza, Eduardo Sada, Esmeralda Juárez, Alfredo Ponce-de-León, José Sifuentes-Osornio, Robert J. Wilkinson, Martha Torres

J Immunol Res. 2019; 2019: 1297131. Published online 2019 Dec 6. doi: 10.1155/2019/1297131

PMCID:: PMC6925913

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Select item 67041542.

Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity

Ursula K. Rohlwink, Anthony Figaji, Katalin A. Wilkinson, Stuart Horswell, Abdul K. Sesay, Armin Deffur, Nico Enslin, Regan Solomons, Ronald Van Toorn, Brian Eley, Michael Levin, Robert J. Wilkinson, Rachel P. J. Lai

Nat Commun. 2019; 10: 3767. Published online 2019 Aug 21. doi: 10.1038/s41467-019-11783-9

PMCID:: PMC6704154

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Select item 69108793.

Tuberculosis Antigen-Specific T-Cell Responses During the First 6 Months of Antiretroviral Treatment

Catherine Riou, Nishtha Jhilmeet, Molebogeng X Rangaka, Robert J Wilkinson, Katalin A Wilkinson

J Infect Dis. 2020 Jan 1; 221(1): 162–167. Published online 2019 Aug 17. doi: 10.1093/infdis/jiz417

PMCID:: PMC6910879

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Select item 66115684.

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study

Charlotte Schutz, David Barr, Bruno B. Andrade, Muki Shey, Amy Ward, Saskia Janssen, Rosie Burton, Katalin A. Wilkinson, Bianca Sossen, Kiyoshi F. Fukutani, Mark Nicol, Gary Maartens, Robert J. Wilkinson, Graeme Meintjes

PLoS Med. 2019 Jul; 16(7): e1002840. Published online 2019 Jul 5. doi: 10.1371/journal.pmed.1002840

PMCID:: PMC6611568

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Select item 62933135.

Improving the microbiological diagnosis of tuberculous meningitis: A prospective, international, multicentre comparison of conventional and modified Ziehl–Neelsen stain, GeneXpert, and culture of cerebrospinal fluid

A. Dorothee Heemskerk, Joseph Donovan, Do Dang Anh Thu, Suzaan Marais, Lidya Chaidir, Vu Thi Mong Dung, Chad M. Centner, Vu Thi Ngoc Ha, Jessi Annisa, Sofiati Dian, Louise Bovijn, Nguyen Thi Hoang Mai, Nguyen Hoan Phu, Nguyen Van Vinh Chau, Ahmad Rizal Ganiem, Cao Thao Van, Ronald B. Geskus, Nguyen Thuy Thuong Thuong, Rovina Ruslami, Graeme Meintjes, Reinout van Crevel, Robert J. Wilkinson, Guy E. Thwaites

J Infect. 2018 Dec; 77(6): 509–515. doi: 10.1016/j.jinf.2018.09.003

PMCID:: PMC6293313

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Select item 62186266.

The Immune Mechanisms of Lung Parenchymal Damage in Tuberculosis and the Role of Host-Directed Therapy

Cari Stek, Brian Allwood, Naomi F. Walker, Robert J. Wilkinson, Lutgarde Lynen, Graeme Meintjes

Front Microbiol. 2018; 9: 2603. Published online 2018 Oct 30. doi: 10.3389/fmicb.2018.02603

PMCID:: PMC6218626

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Select item 65541947.

Transcriptomics in TB: the immune response and diagnosis

Akul Singhania, Robert J. Wilkinson, Marc Rodrigue, Pranabashis Haldar, Anne O’Garra

Nat Immunol. 2018 Nov 1; 19(11): 1159–1168. Published online 2018 Oct 17. doi: 10.1038/s41590-018-0225-9

PMCID:: PMC6554194

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Select item 66032698.

Plasma Biomarkers to Detect Prevalent or Predict Progressive Tuberculosis Associated With Human Immunodeficiency Virus–1

Maia Lesosky, Molebogeng X Rangaka, Cara Pienaar, Anna K Coussens, Rene Goliath, Shaheed Mathee, Judith Mwansa-Kambafwile, Gary Maartens, Robert J Wilkinson, Katalin Andrea Wilkinson

Clin Infect Dis. 2019 Jul 15; 69(2): 295–305. Published online 2018 Sep 26. doi: 10.1093/cid/ciy823

PMCID:: PMC6603269

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Select item 61812759.

The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research

Naomi F. Walker, Cari Stek, Sean Wasserman, Robert J. Wilkinson, Graeme Meintjes

Curr Opin HIV AIDS. 2018 Nov; 13(6): 512–521. Published online 2018 Sep 15. doi: 10.1097/COH.0000000000000502

PMCID:: PMC6181275

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Select item 629347410.

Corticosteroids as an adjunct to tuberculosis therapy

Charlotte Schutz, Angharad G Davis, Bianca Sossen, Rachel P-J Lai, Mpiko Ntsekhe, Yolande XR Harley, Robert J Wilkinson

Expert Rev Respir Med. 2018 Oct; 12(10): 881–891. Published online 2018 Sep 6. doi: 10.1080/17476348.2018.1515628

PMCID:: PMC6293474

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Select item 602008811.

A semi-automatic technique to quantify complex tuberculous lung lesions on ¹⁸F-fluorodeoxyglucose positron emission tomography/computerised tomography images

Stephanus T. Malherbe, Patrick Dupont, Ilse Kant, Petri Ahlers, Magdalena Kriel, André G. Loxton, Ray Y. Chen, Laura E. Via, Friedrich Thienemann, Robert J. Wilkinson, Clifton E. Barry, III, Stephanie Griffith-Richards, Annare Ellman, Katharina Ronacher, Jill Winter, Gerhard Walzl, James M. Warwick, the Catalysis Biomarker Consortium

EJNMMI Res. 2018; 8: 55. Published online 2018 Jun 25. doi: 10.1186/s13550-018-0411-7

PMCID:: PMC6020088

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Select item 600832712.

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

Akul Singhania, Raman Verma, Christine M. Graham, Jo Lee, Trang Tran, Matthew Richardson, Patrick Lecine, Philippe Leissner, Matthew P. R. Berry, Robert J. Wilkinson, Karine Kaiser, Marc Rodrigue, Gerrit Woltmann, Pranabashis Haldar, Anne O’Garra

Nat Commun. 2018; 9: 2308. Published online 2018 Jun 19. doi: 10.1038/s41467-018-04579-w

PMCID:: PMC6008327

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Select item 593448213.

Differential Effect of Viable Versus Necrotic Neutrophils on Mycobacterium tuberculosis Growth and Cytokine Induction in Whole Blood

David M. Lowe, Julie Demaret, Nonzwakazi Bangani, Justine K. Nakiwala, Rene Goliath, Katalin A. Wilkinson, Robert J. Wilkinson, Adrian R. Martineau

Front Immunol. 2018; 9: 903. Published online 2018 Apr 27. doi: 10.3389/fimmu.2018.00903

PMCID:: PMC5934482

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Select item 592572714.

HIV-Associated Mycobacterium tuberculosis Bloodstream Infection Is Underdiagnosed by Single Blood Culture

David A. Barr, Andrew D. Kerkhoff, Charlotte Schutz, Amy M. Ward, Gerry R. Davies, Robert J. Wilkinson, Graeme Meintjes

J Clin Microbiol. 2018 May; 56(5): e01914-17. Prepublished online 2018 Feb 14. Published online 2018 Apr 25. doi: 10.1128/JCM.01914-17

PMCID:: PMC5925727

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Select item 593178515.

The prevalence and determinants of active tuberculosis among diabetes patients in Cape Town, South Africa, a high HIV/TB burden setting

Natacha Berkowitz, Adaeze Okorie, Rene Goliath, Naomi Levitt, Robert J. Wilkinson, Tolu Oni

Diabetes Res Clin Pract. 2018 Apr; 138: 16–25. doi: 10.1016/j.diabres.2018.01.018

PMCID:: PMC5931785

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Select item 576596616.

Neutrophil activation and enhanced release of granule products in HIV-TB immune reconstitution inflammatory syndrome

Justine K Nakiwala, Naomi F Walker, Collin R Diedrich, William Worodria, Graeme Meintjes, Robert J Wilkinson, Harriet Mayanja-Kizza, Robert Colebunders, Luc Kestens, Katalin A Wilkinson, David M Lowe

J Acquir Immune Defic Syndr. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: J Acquir Immune Defic Syndr. 2018 Feb 1; 77(2): 221–229. doi: 10.1097/QAI.0000000000001582

Correction in:: J Acquir Immune Defic Syndr. 2018 Jun 1; 78(2): e13.

PMCID:: PMC5765966

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Select item 584157417.

Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial

Ray Y. Chen, Laura E. Via, Lori E. Dodd, Gerhard Walzl, Stephanus T. Malherbe, André G. Loxton, Rodney Dawson, Robert J. Wilkinson, Friedrich Thienemann, Michele Tameris, Mark Hatherill, Andreas H. Diacon, Xin Liu, Jin Xing, Xiaowei Jin, Zhenya Ma, Shouguo Pan, Guolong Zhang, Qian Gao, Qi Jiang, Hong Zhu, Lili Liang, Hongfei Duan, Taeksun Song, David Alland, Michael Tartakovsky, Alex Rosenthal, Christopher Whalen, Michael Duvenhage, Ying Cai, Lisa C. Goldfeder, Kriti Arora, Bronwyn Smith, Jill Winter, Clifton E. Barry III, Predict TB Study Group

Version 1. Gates Open Res. 2017; 1: 9. Published online 2017 Nov 6. doi: 10.12688/gatesopenres.12750.1

PMCID:: PMC5841574

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Select item 555436618.

Analysis of the Phenotype of Mycobacterium tuberculosis-Specific CD4+ T Cells to Discriminate Latent from Active Tuberculosis in HIV-Uninfected and HIV-Infected Individuals

Catherine Riou, Natacha Berkowitz, Rene Goliath, Wendy A. Burgers, Robert J. Wilkinson

Front Immunol. 2017; 8: 968. Published online 2017 Aug 10. doi: 10.3389/fimmu.2017.00968

PMCID:: PMC5554366

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Select item 553889919.

Trilateral overlap of tuberculosis, diabetes and HIV-1 in a high-burden African setting: implications for TB control

Tolu Oni, Natacha Berkowitz, Mmamapudi Kubjane, Rene Goliath, Naomi S. Levitt, Robert J. Wilkinson

Eur Respir J. 2017 Jul; 50(1): 1700004. Published online 2017 Jul 20. doi: 10.1183/13993003.00004-2017

PMCID:: PMC5538899

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Select item 542707520.

Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes

Neesha Rockwood, Diego L. Costa, Eduardo P. Amaral, Elsa Du Bruyn, Andre Kubler, Leonardo Gil-Santana, Kiyoshi F. Fukutani, Charles A. Scanga, JoAnne L. Flynn, Sharon H. Jackson, Katalin A. Wilkinson, William R. Bishai, Alan Sher, Robert J. Wilkinson, Bruno B. Andrade

Front Immunol. 2017; 8: 542. Published online 2017 May 12. doi: 10.3389/fimmu.2017.00542