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Select item 93504281.

Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice

Liyi Huang, Xin Sun, Lu Wang, Gaiqing Pei, Yang Wang, Qing Zhang, Zejun Liang, Dong Wang, Chenying Fu, Chengqi He, Quan Wei

MedComm (2020) 2022 Sep; 3(3): e160. Published online 2022 Aug 3. doi: 10.1002/mco2.160

PMCID:: PMC9350428

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Select item 78614342.

Pulsed electromagnetic field (PEMF) transiently stimulates the rate of mineralization in a 3-dimensional ring culture model of osteogenesis

Paul D. Benya, Aaron Kavanaugh, Martin Zakarian, Philip Söderlind, Tea Jashashvili, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Fabrizio Billi

PLoS One. 2021; 16(2): e0244223. Published online 2021 Feb 4. doi: 10.1371/journal.pone.0244223

PMCID:: PMC7861434

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Select item 91470613.

Pulsed Electromagnetic Field (PEMF) Treatment Reduces Lipopolysaccharide-Induced Septic Shock in Mice

Chang-Gun Lee, Chanoh Park, Soonjae Hwang, Ju-Eun Hong, Minjeong Jo, Minseob Eom, Yongheum Lee, Ki-Jong Rhee

Int J Mol Sci. 2022 May; 23(10): 5661. Published online 2022 May 18. doi: 10.3390/ijms23105661

PMCID:: PMC9147061

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Select item 94016284.

High-specificity protection against radiation-induced bone loss by a pulsed electromagnetic field

Zedong Yan, Dan Wang, Jing Cai, Liangliang Shen, Maogang Jiang, Xiyu Liu, Jinghui Huang, Yong Zhang, Erping Luo, Da Jing

Sci Adv. 2022 Aug; 8(34): eabq0222. Published online 2022 Aug 24. doi: 10.1126/sciadv.abq0222

PMCID:: PMC9401628

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Select item 57643615.

Effects of pulsed electromagnetic field (PEMF) on the tensile biomechanical properties of diabetic wounds at different phases of healing

Harry M. C. Choi, Alex K. K. Cheing, Gabriel Y. F. Ng, Gladys L. Y. Cheing

PLoS One. 2018; 13(1): e0191074. Published online 2018 Jan 11. doi: 10.1371/journal.pone.0191074

Correction in:: PLoS One. 2018; 13(11): e0208475.

PMCID:: PMC5764361

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Select item 98625616.

Pulsed Electromagnetic Field (PEMF) Treatment Ameliorates Murine Model of Collagen-Induced Arthritis

Ju-Eun Hong, Chang-Gun Lee, Soonjae Hwang, Junyoung Kim, Minjeong Jo, Da-Hye Kang, Sang-Hyeon Yoo, Woo-Seung Kim, Yongheum Lee, Ki-Jong Rhee

Int J Mol Sci. 2023 Jan; 24(2): 1137. Published online 2023 Jan 6. doi: 10.3390/ijms24021137

PMCID:: PMC9862561

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Select item 69027017.

Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism

Jasmine Lye Yee Yap, Yee Kit Tai, Jürg Fröhlich, Charlene Hui Hua Fong, Jocelyn Naixin Yin, Zi Ling Foo, Sharanya Ramanan, Christian Beyer, Shi Jie Toh, Marco Casarosa, Narendra Bharathy, Monica Palanichamy Kala, Marcel Egli, Reshma Taneja, Chuen Neng Lee, Alfredo Franco-Obregón

FASEB J. 2019 Nov; 33(11): 12853–12872. Published online 2019 Sep 13. doi: 10.1096/fj.201900057R

PMCID:: PMC6902701

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Select item 95238328.

In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang

Technol Cancer Res Treat. 2022; 21: 15330338221124658. Published online 2022 Sep 29. doi: 10.1177/15330338221124658

PMCID:: PMC9523832

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Select item 59058569.

Pulsed Electromagnetic Fields and Tissue Engineering of the Joints

Kenjiro Iwasa, A. Hari Reddi

Tissue Eng Part B Rev. 2018 Apr 1; 24(2): 144–154. Published online 2018 Apr 1. doi: 10.1089/ten.teb.2017.0294

PMCID:: PMC5905856

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Select item 897882510.

Pulsed Electromagnetic Field Alleviates Intervertebral Disc Degeneration by Activating Sirt1-Autophagy Signaling Network

Yi Zheng, Liangwei Mei, Shengyou Li, Teng Ma, Bing Xia, Yiming Hao, Xue Gao, Bin Wei, Yitao Wei, Da Jing, Zhuojing Luo, Jinghui Huang

Front Bioeng Biotechnol. 2022; 10: 853872. Published online 2022 Mar 21. doi: 10.3389/fbioe.2022.853872

PMCID:: PMC8978825

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Select item 881895811.

Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach

Yee Kit Tai, Karen Ka Wing Chan, Charlene Hui Hua Fong, Sharanya Ramanan, Jasmine Lye Yee Yap, Jocelyn Naixin Yin, Yun Sheng Yip, Wei Ren Tan, Angele Pei Fern Koh, Nguan Soon Tan, Ching Wan Chan, Ruby Yun Ju Huang, Jing Ze Li, Jürg Fröhlich, Alfredo Franco-Obregón

Front Oncol. 2021; 11: 783803. Published online 2022 Jan 24. doi: 10.3389/fonc.2021.783803

Correction in:: Front Oncol. 2022; 12: 892408.

PMCID:: PMC8818958

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Select item 694762412.

Translational Insights into Extremely Low Frequency Pulsed Electromagnetic Fields (ELF-PEMFs) for Bone Regeneration after Trauma and Orthopedic Surgery

Sabrina Ehnert, Steffen Schröter, Romina H. Aspera-Werz, Wiebke Eisler, Karsten Falldorf, Michael Ronniger, Andreas K. Nussler

J Clin Med. 2019 Dec; 8(12): 2028. Published online 2019 Nov 20. doi: 10.3390/jcm8122028

PMCID:: PMC6947624

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Select item 542042413.

Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation

Nagarajan Selvamurugan, Zhiming He, Daniel Rifkin, Branka Dabovic, Nicola C. Partridge

Stem Cells Int. 2017; 2017: 2450327. Published online 2017 Apr 23. doi: 10.1155/2017/2450327

PMCID:: PMC5420424

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Select item 692068314.

Pulsed electromagnetic fields reduce acute inflammation in the injured rat‐tail intervertebral disc

Andrew K. Chan, Xinyan Tang, Nikhil V. Mummaneni, Dezba Coughlin, Ellen Liebenberg, Annie Ouyang, Stefan Dudli, Michael Lauricella, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Jeffrey C. Lotz

JOR Spine. 2019 Dec; 2(4): e1069. Published online 2019 Dec 2. doi: 10.1002/jsp2.1069

PMCID:: PMC6920683

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Select item 894572215.

Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage

Mattia Di Bartolomeo, Francesco Cavani, Arrigo Pellacani, Alexis Grande, Roberta Salvatori, Luigi Chiarini, Riccardo Nocini, Alexandre Anesi

Biology (Basel) 2022 Mar; 11(3): 402. Published online 2022 Mar 5. doi: 10.3390/biology11030402

PMCID:: PMC8945722

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Select item 883544716.

Induced Neurodifferentiation of hBM-MSCs through Activation of the ERK/CREB Pathway via Pulsed Electromagnetic Fields and Physical Stimulation Promotes Neurogenesis in Cerebral Ischemic Models

Hee-Jung Park, Ju-Hye Choi, Myeong-Hyun Nam, Young-Kwon Seo

Int J Mol Sci. 2022 Feb; 23(3): 1177. Published online 2022 Jan 21. doi: 10.3390/ijms23031177

PMCID:: PMC8835447

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Select item 906861917.

Pulsed electromagnetic fields inhibit mandibular bone deterioration depending on the Wnt3a/β-catenin signaling activation in type 2 diabetic db/db mice

Jianjun Li, Jing Cai, Liheng Liu, Yuwei Wu, Yan Chen

Sci Rep. 2022; 12: 7217. Published online 2022 May 4. doi: 10.1038/s41598-022-10065-7

PMCID:: PMC9068619

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Select item 616811818.

Low-intensity electromagnetic fields induce human cryptochrome to modulate intracellular reactive oxygen species

Rachel M. Sherrard, Natalie Morellini, Nathalie Jourdan, Mohamed El-Esawi, Louis-David Arthaut, Christine Niessner, Francois Rouyer, Andre Klarsfeld, Mohamed Doulazmi, Jacques Witczak, Alain d’Harlingue, Jean Mariani, Ian Mclure, Carlos F. Martino, Margaret Ahmad

PLoS Biol. 2018 Oct; 16(10): e2006229. Published online 2018 Oct 2. doi: 10.1371/journal.pbio.2006229

PMCID:: PMC6168118

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Select item 897568819.

Circadian Rhythm Modulates the Therapeutic Activity of Pulsed Electromagnetic Fields on Intervertebral Disc Degeneration in Rats

Yi Zheng, Yiming Hao, Bing Xia, Liangwei Mei, Shengyou Li, Xue Gao, Teng Ma, Bin Wei, Zhifen Tan, Pingheng Lan, Zhuojing Luo, Da Jing, Jinghui Huang

Oxid Med Cell Longev. 2022; 2022: 9067611. Published online 2022 Mar 25. doi: 10.1155/2022/9067611

PMCID:: PMC8975688

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Select item 957657220.

Enhancing cartilage repair with optimized supramolecular hydrogel-based scaffold and pulsed electromagnetic field

Yucong Li, Linlong Li, Ye Li, Lu Feng, Bin Wang, Ming Wang, Haixing Wang, Meiling Zhu, Yongkang Yang, Erik I. Waldorff, Nianli Zhang, Ingmar Viohl, Sien Lin, Liming Bian, Wayne Yuk-Wai Lee, Gang Li

Bioact Mater. 2023 Apr; 22: 312–324. Published online 2022 Oct 12. doi: 10.1016/j.bioactmat.2022.10.010

PMCID:: PMC9576572

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Figure 11

Comparison of IL-10 and VEGF expression between experimental and control groups. (a) Analysis of IL-10 levels in cultures exposed to FGF-2 and PEMF (2 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (b) Analysis of IL-10 levels in cultures exposed to FGF-2 and PEMF (4 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (c) Analysis of IL-10 levels in cultures exposed to FGF-2 and PEMF (8 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (d) Analysis of VEGF levels in cultures exposed to FGF-2 and PEMF (2 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (e) Analysis of VEGF levels in cultures exposed to FGF-2 and PEMF (4 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (f) Analysis of VEGF levels in cultures exposed to FGF-2 and PEMF (8 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days.

Pulsed Electromagnetic Fields Improve Tenogenic Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells: A Potential Strategy for Tendon Repair—An In Vitro Study

Stem Cells Int. 2018;2018:9048237.
Figure 12

Evaluation of cell mortality in UC-MSC cultures exposed to PEMF. (a) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (2 h/day) after 7 days. (b) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (4 h/day) after 7 days. (c) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (8 h/day) after 7 days. (d) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (2 h/day) after 14 days. (e) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (4 h/day) after 14 days. (f) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (8 h/day) after 14 days. (g) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (2 h/day) after 21 days. (h) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (4 h/day) after 21 days. (i) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (8 h/day) after 21 days.

Pulsed Electromagnetic Fields Improve Tenogenic Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells: A Potential Strategy for Tendon Repair—An In Vitro Study

Stem Cells Int. 2018;2018:9048237.
Fig 7Micro-CT-derived density profiles at Day 27.

Total HA vs. HA mg/ml was plotted, and profiles compared between no-PEMF controls and PEMF treatment between Day 1- Day 10 (a); PEMF between Day 11-Day 27 (b); PEMF between Day 28-Day 63 (c); and Daily PEMF (d). In each case, n = 3 and the lines are the means, and thicknesses represent the standard error. Control values were also subtracted from PEMF values at each density to yield a difference plot (orange) to visualize the effect of PEMF on mineral density.

Pulsed electromagnetic field (PEMF) transiently stimulates the rate of mineralization in a 3-dimensional ring culture model of osteogenesis

PLoS One. 2021;16(2):e0244223.
Fig 8Micro-CT-derived 3D distribution of voxels in the density range maximally influenced by PEMF on Day 63.

Constructs treated with Daily PEMF (left panel) and no-PEMF controls (right panel). The density range presented is 200–225 HA mg/ml.

Pulsed electromagnetic field (PEMF) transiently stimulates the rate of mineralization in a 3-dimensional ring culture model of osteogenesis

PLoS One. 2021;16(2):e0244223.