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Select item 93504281.

Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice

Liyi Huang, Xin Sun, Lu Wang, Gaiqing Pei, Yang Wang, Qing Zhang, Zejun Liang, Dong Wang, Chenying Fu, Chengqi He, Quan Wei

MedComm (2020) 2022 Sep; 3(3): e160. Published online 2022 Aug 3. doi: 10.1002/mco2.160

PMCID:: PMC9350428

Abstract Article PDF–11M

Select item 103793032.

Pulsed Electromagnetic Fields (PEMF)—Physiological Response and Its Potential in Trauma Treatment

Jonas Flatscher, Elizabeth Pavez Loriè, Rainer Mittermayr, Paul Meznik, Paul Slezak, Heinz Redl, Cyrill Slezak

Int J Mol Sci. 2023 Jul; 24(14): 11239. Published online 2023 Jul 8. doi: 10.3390/ijms241411239

PMCID:: PMC10379303

Abstract Article PDF–435K

Select item 78614343.

Pulsed electromagnetic field (PEMF) transiently stimulates the rate of mineralization in a 3-dimensional ring culture model of osteogenesis

Paul D. Benya, Aaron Kavanaugh, Martin Zakarian, Philip Söderlind, Tea Jashashvili, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Fabrizio Billi

PLoS One. 2021; 16(2): e0244223. Published online 2021 Feb 4. doi: 10.1371/journal.pone.0244223

PMCID:: PMC7861434

Abstract Article PDF–6.7M

Select item 114432224.

Pulsed Electromagnetic Field (PEMF) stimulation as an adjunct to exercise: a brief review

Sheyda Ghanbari Ghoshchi, Maria Letizia Petroni, Alessandro Piras, Samuele Maria Marcora, Milena Raffi

Front Sports Act Living. 2024; 6: 1471087. Published online 2024 Sep 9. doi: 10.3389/fspor.2024.1471087

PMCID:: PMC11443222

Abstract Article PDF–303K

Select item 91470615.

Pulsed Electromagnetic Field (PEMF) Treatment Reduces Lipopolysaccharide-Induced Septic Shock in Mice

Chang-Gun Lee, Chanoh Park, Soonjae Hwang, Ju-Eun Hong, Minjeong Jo, Minseob Eom, Yongheum Lee, Ki-Jong Rhee

Int J Mol Sci. 2022 May; 23(10): 5661. Published online 2022 May 18. doi: 10.3390/ijms23105661

PMCID:: PMC9147061

Abstract Article PDF–3.7M

Select item 98625616.

Pulsed Electromagnetic Field (PEMF) Treatment Ameliorates Murine Model of Collagen-Induced Arthritis

Ju-Eun Hong, Chang-Gun Lee, Soonjae Hwang, Junyoung Kim, Minjeong Jo, Da-Hye Kang, Sang-Hyeon Yoo, Woo-Seung Kim, Yongheum Lee, Ki-Jong Rhee

Int J Mol Sci. 2023 Jan; 24(2): 1137. Published online 2023 Jan 6. doi: 10.3390/ijms24021137

PMCID:: PMC9862561

Abstract Article PDF–3.6M

Select item 94016287.

High-specificity protection against radiation-induced bone loss by a pulsed electromagnetic field

Zedong Yan, Dan Wang, Jing Cai, Liangliang Shen, Maogang Jiang, Xiyu Liu, Jinghui Huang, Yong Zhang, Erping Luo, Da Jing

Sci Adv. 2022 Aug; 8(34): eabq0222. Published online 2022 Aug 24. doi: 10.1126/sciadv.abq0222

PMCID:: PMC9401628

Abstract Article PDF–16M

Select item 57643618.

Effects of pulsed electromagnetic field (PEMF) on the tensile biomechanical properties of diabetic wounds at different phases of healing

Harry M. C. Choi, Alex K. K. Cheing, Gabriel Y. F. Ng, Gladys L. Y. Cheing

PLoS One. 2018; 13(1): e0191074. Published online 2018 Jan 11. doi: 10.1371/journal.pone.0191074

Correction in:: PLoS One. 2018; 13(11): e0208475.

PMCID:: PMC5764361

Abstract Article PDF–655K

Select item 95238329.

In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang

Technol Cancer Res Treat. 2022; 21: 15330338221124658. Published online 2022 Sep 29. doi: 10.1177/15330338221124658

PMCID:: PMC9523832

Abstract Article PDF–5.5M

Select item 690270110.

Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism

Jasmine Lye Yee Yap, Yee Kit Tai, Jürg Fröhlich, Charlene Hui Hua Fong, Jocelyn Naixin Yin, Zi Ling Foo, Sharanya Ramanan, Christian Beyer, Shi Jie Toh, Marco Casarosa, Narendra Bharathy, Monica Palanichamy Kala, Marcel Egli, Reshma Taneja, Chuen Neng Lee, Alfredo Franco-Obregón

FASEB J. 2019 Nov; 33(11): 12853–12872. Published online 2019 Sep 13. doi: 10.1096/fj.201900057R

PMCID:: PMC6902701

Abstract Article

Select item 901339311.

Pulsed Electromagnetic Field Therapy Alters Early Healing in a Rat Model of Rotator Cuff Injury and Repair: Potential Mechanisms

Julianne Huegel, Peter Y.W. Chan, Stephanie N. Weiss, Courtney A. Nuss, Harina Raja, Erik I. Waldorff, Nianli Zhang, James T. Ryaby, Louis J. Soslowsky, Andrew F. Kuntz

J Orthop Res. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: J Orthop Res. 2022 Jul; 40(7): 1593–1603. Published online 2021 Oct 17. doi: 10.1002/jor.25185

PMCID:: PMC9013393

Abstract Article PDF–1.6M

Select item 897882512.

Pulsed Electromagnetic Field Alleviates Intervertebral Disc Degeneration by Activating Sirt1-Autophagy Signaling Network

Yi Zheng, Liangwei Mei, Shengyou Li, Teng Ma, Bing Xia, Yiming Hao, Xue Gao, Bin Wei, Yitao Wei, Da Jing, Zhuojing Luo, Jinghui Huang

Front Bioeng Biotechnol. 2022; 10: 853872. Published online 2022 Mar 21. doi: 10.3389/fbioe.2022.853872

PMCID:: PMC8978825

Abstract Article PDF–4.9M

Select item 590585613.

Pulsed Electromagnetic Fields and Tissue Engineering of the Joints

Kenjiro Iwasa, A. Hari Reddi

Tissue Eng Part B Rev. 2018 Apr 1; 24(2): 144–154. Published online 2018 Apr 1. doi: 10.1089/ten.teb.2017.0294

PMCID:: PMC5905856

Abstract Article PDF–292K

Select item 881895814.

Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach

Yee Kit Tai, Karen Ka Wing Chan, Charlene Hui Hua Fong, Sharanya Ramanan, Jasmine Lye Yee Yap, Jocelyn Naixin Yin, Yun Sheng Yip, Wei Ren Tan, Angele Pei Fern Koh, Nguan Soon Tan, Ching Wan Chan, Ruby Yun Ju Huang, Jing Ze Li, Jürg Fröhlich, Alfredo Franco-Obregón

Front Oncol. 2021; 11: 783803. Published online 2022 Jan 24. doi: 10.3389/fonc.2021.783803

Correction in:: Front Oncol. 2022; 12: 892408.

PMCID:: PMC8818958

Abstract Article PDF–9.5M

Select item 1057222715.

NET Formation Was Reduced via Exposure to Extremely Low-Frequency Pulsed Electromagnetic Fields

Caren Linnemann, Filiz Sahin, Yangmengfan Chen, Karsten Falldorf, Michael Ronniger, Tina Histing, Andreas K. Nussler, Sabrina Ehnert

Int J Mol Sci. 2023 Oct; 24(19): 14629. Published online 2023 Sep 27. doi: 10.3390/ijms241914629

PMCID:: PMC10572227

Abstract Article PDF–2.2M

Select item 694762416.

Translational Insights into Extremely Low Frequency Pulsed Electromagnetic Fields (ELF-PEMFs) for Bone Regeneration after Trauma and Orthopedic Surgery

Sabrina Ehnert, Steffen Schröter, Romina H. Aspera-Werz, Wiebke Eisler, Karsten Falldorf, Michael Ronniger, Andreas K. Nussler

J Clin Med. 2019 Dec; 8(12): 2028. Published online 2019 Nov 20. doi: 10.3390/jcm8122028

PMCID:: PMC6947624

Abstract Article PDF–1.7M

Select item 894572217.

Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage

Mattia Di Bartolomeo, Francesco Cavani, Arrigo Pellacani, Alexis Grande, Roberta Salvatori, Luigi Chiarini, Riccardo Nocini, Alexandre Anesi

Biology (Basel) 2022 Mar; 11(3): 402. Published online 2022 Mar 5. doi: 10.3390/biology11030402

PMCID:: PMC8945722

Abstract Article PDF–519K

Select item 692068318.

Pulsed electromagnetic fields reduce acute inflammation in the injured rat‐tail intervertebral disc

Andrew K. Chan, Xinyan Tang, Nikhil V. Mummaneni, Dezba Coughlin, Ellen Liebenberg, Annie Ouyang, Stefan Dudli, Michael Lauricella, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Jeffrey C. Lotz

JOR Spine. 2019 Dec; 2(4): e1069. Published online 2019 Dec 2. doi: 10.1002/jsp2.1069

PMCID:: PMC6920683

Abstract Article PDF–5.3M

Select item 976988419.

Pulsed Electromagnetic Fields Disrupt Staphylococcus epidermidis Biofilms and Enhance the Antibiofilm Efficacy of Antibiotics

Ryan B. Juncker, Beth A. Lazazzera, Fabrizio Billi

Microbiol Spectr. 2022 Nov-Dec; 10(6): e01949-22. Published online 2022 Oct 31. doi: 10.1128/spectrum.01949-22

PMCID:: PMC9769884

Abstract Article PDF–1.1M

Select item 1070635820.

Pulsed Electromagnetic Fields Induce Skeletal Muscle Cell Repair by Sustaining the Expression of Proteins Involved in the Response to Cellular Damage and Oxidative Stress

Silvia Maiullari, Antonella Cicirelli, Angela Picerno, Francesca Giannuzzi, Loreto Gesualdo, Angela Notarnicola, Fabio Sallustio, Biagio Moretti

Int J Mol Sci. 2023 Dec; 24(23): 16631. Published online 2023 Nov 23. doi: 10.3390/ijms242316631

PMCID:: PMC10706358

Abstract Article PDF–2.8M

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Figure 11

Comparison of IL-10 and VEGF expression between experimental and control groups. (a) Analysis of IL-10 levels in cultures exposed to FGF-2 and PEMF (2 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (b) Analysis of IL-10 levels in cultures exposed to FGF-2 and PEMF (4 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (c) Analysis of IL-10 levels in cultures exposed to FGF-2 and PEMF (8 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (d) Analysis of VEGF levels in cultures exposed to FGF-2 and PEMF (2 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (e) Analysis of VEGF levels in cultures exposed to FGF-2 and PEMF (4 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days. (f) Analysis of VEGF levels in cultures exposed to FGF-2 and PEMF (8 h/day) compared to cultures exposed only to FGF-2 and cultures without PEMF and FGF-2 exposures after 7, 14, and 21 days.

Pulsed Electromagnetic Fields Improve Tenogenic Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells: A Potential Strategy for Tendon Repair—An In Vitro Study

Stem Cells Int. 2018;2018:9048237.
Figure 12

Evaluation of cell mortality in UC-MSC cultures exposed to PEMF. (a) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (2 h/day) after 7 days. (b) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (4 h/day) after 7 days. (c) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (8 h/day) after 7 days. (d) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (2 h/day) after 14 days. (e) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (4 h/day) after 14 days. (f) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (8 h/day) after 14 days. (g) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (2 h/day) after 21 days. (h) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (4 h/day) after 21 days. (i) FACS analysis of annexin V/propidium iodide in cultures exposed to FGF-2 and PEMF (8 h/day) after 21 days.

Pulsed Electromagnetic Fields Improve Tenogenic Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells: A Potential Strategy for Tendon Repair—An In Vitro Study

Stem Cells Int. 2018;2018:9048237.
Fig 7Micro-CT-derived density profiles at Day 27.

Total HA vs. HA mg/ml was plotted, and profiles compared between no-PEMF controls and PEMF treatment between Day 1- Day 10 (a); PEMF between Day 11-Day 27 (b); PEMF between Day 28-Day 63 (c); and Daily PEMF (d). In each case, n = 3 and the lines are the means, and thicknesses represent the standard error. Control values were also subtracted from PEMF values at each density to yield a difference plot (orange) to visualize the effect of PEMF on mineral density.

Pulsed electromagnetic field (PEMF) transiently stimulates the rate of mineralization in a 3-dimensional ring culture model of osteogenesis

PLoS One. 2021;16(2):e0244223.
Fig 8Micro-CT-derived 3D distribution of voxels in the density range maximally influenced by PEMF on Day 63.

Constructs treated with Daily PEMF (left panel) and no-PEMF controls (right panel). The density range presented is 200–225 HA mg/ml.

Pulsed electromagnetic field (PEMF) transiently stimulates the rate of mineralization in a 3-dimensional ring culture model of osteogenesis

PLoS One. 2021;16(2):e0244223.