Key inflammation modulating signals during wound healing.
Figure CITATIONS
Dienz O., Eaton SM., Bond JP. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. J Exp. Med. 2009;206:69–78.
Yasukawa H., Ohishi M., Mori H., Murakami M., Chinen T., Aki D., Hanada T., Takeda K., Akira S., Hoshijima M., Hirano T., Chien KR., Yoshimura A. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol. 2003;(4):551–556.
Gallucci RM., Sugawara T., Yucesoy B., Berryann K., Simeonova PP., Matheson JM., Luster MI. Interleukin-6 treatment augments cutaneous wound healing in immunosuppressed mice. J Interferon Cytokine Res. 2001;21(8):603–609.
Schroeder JM., Christophers E. Identification of C5a des arg and an anionic neutrophil-activating peptide (ANAP) in psoriatic scales. J Invest. Dermatol. 1986;87:53–58.
Yoshimura T., Matsushima K., Oppenheim JJ, Leonard EJ Neutrophil chemotactic factor produced by lipopolysaccharide (LPS)-stimulated human blood mononuclear leukocytes: partial characterization and separation from interleukin 1 (IL 1). J Immunol. 1987;139:788–793.
Baggiolini M., Dewald B., Moser B. Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv Immunol. 1994;55:97–179.
Koch AE., Polverini PJ, Kunkel SL., Harlow LA., DiPietro LA., Elner VM., Elner SG., Strieter RM. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science. 1992;258:1798–1801.
Strieter RM., Polverini PJ, Kunkel SL., Arenberg DA., Burdick MD., Kasper J, Dzuiba J, Damme JV., Walz A., Marriott D. The functional role of the ‘ELR’ motif in CXC chemokine-mediated angiogenesis. J Biol. Chem. 1995;270:27348–27357.
Yao M., Zhou RH., Petreaca M., Zheng L., Shyy J, Martins-Green M. Activation of sterol regulatory element-binding proteins (SREBPs) is critical in IL-8-induced angiogenesis. J Leukoc. Biol. 2006;80:608.
Terasaki K., Kanzaki T., Aoki T., Iwata K., Saiki I. Effects of recombinant human tissue inhibitor of metalloproteinases-2 (rhTIMP-2) on migration of epidermal keratinocytes in vitro and wound healing in vivo. J Dermatol. 2003;30(3):165–172.
Deshmane SL., Kremlev S., Amini S., Sawaya BE. Monocyte Chemoattractant Protein (MCP-1): An Overview. J Interferon Cytokine Res. 2009;29(6):313–326
Yang M., Ma B., Shao H., Clark AM., Wells A. Macrophage phenotypic subtypes diametrically regulate epithelial- mesenchymal plasticity in breast cancer cells. BMC Cancer. 2016;16:419.
Bosurgi L., Cao YG., Cabeza-Cabrerizo M., Tucci A., Hughes LD., Kong Y., Weinstein JS., Licona-Limon P., Schmid ET., Pelorosso F., Gagliani N., Craft JE., Flavell RA., Ghosh S., Rothlin CV. Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells. Science. 2017;356(6342): 1072–1076.
Bao P., Kodra A., Tomic-Canic M., Golinko MS., Ehrlich HP., Brem H. The Role of Vascular Endothelial Growth Factor in Wound Healing. J Surg. Res. 2009;152(2):347–358
Engelhardt E., Toksoy A., Goebeler M., Debus S., Bröcker EB., Gillitzer R. Chemokines IL-8, GROα, MCP-1, IP-10, and Mig Are Sequentially and Differentially Expressed During Phase-Specific Infiltration of Leukocyte Subsets in Human Wound Healing. Am. J Pathol. 1998;53(6):1849–1860.
Bodnar RJ, Yates CC., Rodgers ME., Du X., Wells A. IP-10 induces dissociation of newly formed blood vessels. J Cell Sci. 2009;122(Pt 12):2064.