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Items: 19

Select item 85842761.

The Concentration of Organic Acids in Cranberry Juice Modulates the Gut Microbiota in Mice

Valentine Renaud, Vanessa P. Houde, Geneviève Pilon, Thibault V. Varin, Cyril Roblet, André Marette, Yvan Boutin, Laurent Bazinet

Int J Mol Sci. 2021 Nov; 22(21): 11537. Published online 2021 Oct 26. doi: 10.3390/ijms222111537

PMCID:: PMC8584276

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Select item 84291042.

Salsalate reduces atherosclerosis through AMPKβ1 in mice

Emily A. Day, Rebecca J. Ford, Brennan K. Smith, Vanessa P. Houde, Stephanie Stypa, Sonia Rehal, Sarka Lhotak, Bruce E. Kemp, Bernardo L. Trigatti, Geoff H. Werstuck, Richard C. Austin, Morgan D. Fullerton, Gregory R. Steinberg

Mol Metab. 2021 Nov; 53: 101321. Published online 2021 Aug 21. doi: 10.1016/j.molmet.2021.101321

PMCID:: PMC8429104

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Select item 48893273.

The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids

Gerta Hoxhaj, Edward Caddye, Ayaz Najafov, Vanessa P Houde, Catherine Johnson, Kumara Dissanayake, Rachel Toth, David G Campbell, Alan R Prescott, Carol MacKintosh

eLife. 2016; 5: e12278. Published online 2016 Apr 22. doi: 10.7554/eLife.12278

PMCID:: PMC4889327

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Select item 38983224.

Investigation of LKB1 Ser⁴³¹ phosphorylation and Cys⁴³³ farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity

Vanessa P. Houde, Maria Stella Ritorto, Robert Gourlay, Joby Varghese, Paul Davies, Natalia Shpiro, Kei Sakamoto, Dario R. Alessi

Biochem J. 2014 Feb 15; 458(Pt 1): 41–56. Prepublished online 2013 Dec 3. Published online 2014 Jan 20. doi: 10.1042/BJ20131324

PMCID:: PMC3898322

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Select item 31298935.

Conservation of Na⁺ vs. K⁺ by the rat cortical collecting duct

Gustavo Frindt, Véronique Houde, Lawrence G. Palmer

Am J Physiol Renal Physiol. 2011 Jul; 301(1): F14–F20. Published online 2011 Mar 30. doi: 10.1152/ajprenal.00705.2010

PMCID:: PMC3129893

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Select item 28746946.

Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue

Vanessa P. Houde, Sophie Brûlé, William T. Festuccia, Pierre-Gilles Blanchard, Kerstin Bellmann, Yves Deshaies, André Marette

Diabetes. 2010 Jun; 59(6): 1338–1348. Published online 2010 Mar 18. doi: 10.2337/db09-1324

PMCID:: PMC2874694

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Select item 103096367.

Porphyromonas gingivalis under palmitate-induced obesogenic microenvironment modulates the inflammatory transcriptional signature of macrophage-like cells

Xavier Minne, Joanna Mbuya Malaïka Mutombo, Fatiha Chandad, Roberto D. Fanganiello, Vanessa P. Houde

PLoS One. 2023; 18(6): e0288009. Published online 2023 Jun 29. doi: 10.1371/journal.pone.0288009

PMCID:: PMC10309636

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Select item 102188618.

Multi-Omics Data Integration Reveals Key Variables Contributing to Subgingival Microbiome Dysbiosis-Induced Inflammatory Response in a Hyperglycemic Microenvironment

Sarah Lafleur, Antoine Bodein, Joanna Mbuya Malaïka Mutombo, Alban Mathieu, Charles Joly Beauparlant, Xavier Minne, Fatiha Chandad, Arnaud Droit, Vanessa P. Houde

Int J Mol Sci. 2023 May; 24(10): 8832. Published online 2023 May 16. doi: 10.3390/ijms24108832

PMCID:: PMC10218861

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Select item 81848939.

Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice

Béatrice S.-Y. Choi, Noëmie Daniel, Vanessa P. Houde, Adia Ouellette, Bruno Marcotte, Thibault V. Varin, Cécile Vors, Perrine Feutry, Olga Ilkayeva, Marcus Ståhlman, Philippe St-Pierre, Fredrik Bäckhed, Angelo Tremblay, Phillip J. White, André Marette

Nat Commun. 2021; 12: 3377. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23782-w

PMCID:: PMC8184893

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Select item 769061610.

Animal and Cellular Studies Demonstrate Some of the Beneficial Impacts of Herring Milt Hydrolysates on Obesity-Induced Glucose Intolerance and Inflammation

Rachel Durand, Adia Ouellette, Vanessa P. Houde, Frédéric Guénard, Thibaut V. Varin, Bruno Marcotte, Geneviève Pilon, Erwann Fraboulet, Marie-Claude Vohl, André Marette, Laurent Bazinet

Nutrients. 2020 Nov; 12(11): 3235. Published online 2020 Oct 22. doi: 10.3390/nu12113235

PMCID:: PMC7690616

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Select item 669070911.

Inhibition of mitochondrial complex 1 by the S6K1 inhibitor PF-4708671 partly contributes to its glucose metabolic effects in muscle and liver cells

Michael Shum, Vanessa P. Houde, Vicky Bellemare, Rafael Junges Moreira, Kerstin Bellmann, Philippe St-Pierre, Benoit Viollet, Marc Foretz, André Marette

J Biol Chem. 2019 Aug 9; 294(32): 12250–12260. Published online 2019 Jun 26. doi: 10.1074/jbc.RA119.008488

PMCID:: PMC6690709

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Select item 657458112.

Dietary Proteins Relevant to Human Consumption Impact the Development of Obesity and Type 2 Diabetes in Association with Major Changes in the Gut Microbiota in a Mouse Model (OR27-03-19)

Noëmie Daniel, Béatrice Choi, Vanessa Houde, Thibault Varin, Cecile Vors, Philippe St-Pierre, André Marette

Curr Dev Nutr. 2019 Jun; 3(Suppl 1): nzz046.OR27-03-19. Published online 2019 Jun 13. doi: 10.1093/cdn/nzz046.OR27-03-19

PMCID:: PMC6574581

Abstract PDF–46K Cite

Select item 664329713.

Inhibition of acetyl-CoA carboxylase (ACC) by phosphorylation or by the liver-specific inhibitor, ND-654, suppresses lipogenesis and hepatocellular carcinoma

James S.V. Lally, Sarani Ghoshal, Danielle K. DePeralta, Omeed Moaven, Lan Wei, Ricard Masia, Derek J. Erstad, Naoto Fujiwara, Vivian Leong, Vanessa P. Houde, Alexander E. Anagnostopoulos, Alice Wang, Lindsay A. Broadfield, Rebecca J. Ford, Robert A. Foster, Jamie Bates, Hailing Sun, Ting Wang, Henry Liu, Adrian S. Ray, Asish K. Saha, Jeremy Greenwood, Sathesh Bhat, Geraldine Harriman, Wenyan Miao, Jennifer L. Rocnik, William F. Westlin, Paola Muti, Theodoros Tsakiridis, H. James Harwood, Jr, Rosana Kapeller, Yujin Hoshida, Kenneth K. Tanabe, Gregory R. Steinberg, Bryan C. Fuchs

Cell Metab. Author manuscript; available in PMC 2020 Jan 8.

Published in final edited form as: Cell Metab. 2019 Jan 8; 29(1): 174–182.e5. Published online 2018 Sep 20. doi: 10.1016/j.cmet.2018.08.020

PMCID:: PMC6643297

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Select item 557933214.

AMPK β1 reduces tumor progression and improves survival in p53 null mice

Vanessa P. Houde, Sara Donzelli, Andrea Sacconi, Sandra Galic, Joanne A. Hammill, Jonathan L. Bramson, Robert A. Foster, Theodoros Tsakiridis, Bruce E. Kemp, Giuseppe Grasso, Giovanni Blandino, Paola Muti, Gregory R. Steinberg

Mol Oncol. 2017 Sep; 11(9): 1143–1155. Published online 2017 Jun 28. doi: 10.1002/1878-0261.12079

PMCID:: PMC5579332

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Select item 503468415.

The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration

Linda A. Villani, Brennan K. Smith, Katarina Marcinko, Rebecca J. Ford, Lindsay A. Broadfield, Alex E. Green, Vanessa P. Houde, Paola Muti, Theodoros Tsakiridis, Gregory R. Steinberg

Mol Metab. 2016 Oct; 5(10): 1048–1056. Published online 2016 Aug 26. doi: 10.1016/j.molmet.2016.08.014

PMCID:: PMC5034684

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Select item 523344216.

Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1

Brennan K. Smith, Rebecca J. Ford, Eric M. Desjardins, Alex E. Green, Meghan C. Hughes, Vanessa P. Houde, Emily A. Day, Katarina Marcinko, Justin D. Crane, Emilio P. Mottillo, Christopher G.R. Perry, Bruce E. Kemp, Mark A. Tarnopolsky, Gregory R. Steinberg

Diabetes. Author manuscript; available in PMC 2017 Jan 12.

Published in final edited form as: Diabetes. 2016 Nov; 65(11): 3352–3361. Published online 2016 Aug 23. doi: 10.2337/db16-0564

PMCID:: PMC5233442

Article PubReader PDF–980K Cite

Select item 335181817.

Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion

Pierre-Gilles Blanchard, William T. Festuccia, Vanessa P. Houde, Philippe St-Pierre, Sophie Brûlé, Véronique Turcotte, Marie Côté, Kerstin Bellmann, André Marette, Yves Deshaies

J Lipid Res. 2012 Jun; 53(6): 1117–1125. doi: 10.1194/jlr.M021485

PMCID:: PMC3351818

Article PubReader PDF–665K Cite

Select item 368221118.

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

FARHAT V. N. DIN, ASTA VALANCIUTE, VANESSA P. HOUDE, DARIA ZIBROVA, KEVIN A. GREEN, KEI SAKAMOTO, DARIO R. ALESSI, MALCOLM G. DUNLOP

Gastroenterology. Author manuscript; available in PMC 2013 Jun 14.

Published in final edited form as: Gastroenterology. 2012 Jun; 142(7): 1504–15.e3. Published online 2012 Mar 6. doi: 10.1053/j.gastro.2012.02.050

PMCID:: PMC3682211

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Select item 541753719.

Chronic Inhibition of the mTORC1/S6K1 Pathway Increases Insulin-Induced PI3K Activity but Inhibits Akt2 and Glucose Transport Stimulation in 3T3-L1 Adipocytes

Alain Veilleux, Vanessa P. Houde, Kerstin Bellmann, André Marette

Mol Endocrinol. April 1, 2010; 24(4): 766–778. doi: 10.1210/me.2009-0328

PMCID:: PMC5417537

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