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Select item 112538861.

Regulation of PPARγ2 Stability and Activity by SHP-1

Amit Kumar, Beisy Laborit Labrada, Marie-Hélène Lavallée-Bourget, Marie-Pier Forest, Michael Schwab, Kerstin Bellmann, Vanessa Houde, Nicole Beauchemin, Mathieu Laplante, André Marette

Mol Cell Biol. 2024; 44(7): 261–272. Published online 2024 Jun 3. doi: 10.1080/10985549.2024.2354959

PMCID:: PMC11253886

Abstract Article PDF–1.7M

Select item 84291042.

Salsalate reduces atherosclerosis through AMPKβ1 in mice

Emily A. Day, Rebecca J. Ford, Brennan K. Smith, Vanessa P. Houde, Stephanie Stypa, Sonia Rehal, Sarka Lhotak, Bruce E. Kemp, Bernardo L. Trigatti, Geoff H. Werstuck, Richard C. Austin, Morgan D. Fullerton, Gregory R. Steinberg

Mol Metab. 2021 Nov; 53: 101321. Published online 2021 Aug 21. doi: 10.1016/j.molmet.2021.101321

PMCID:: PMC8429104

Abstract Article PDF–1.8M

Select item 81848933.

Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice

Béatrice S.-Y. Choi, Noëmie Daniel, Vanessa P. Houde, Adia Ouellette, Bruno Marcotte, Thibault V. Varin, Cécile Vors, Perrine Feutry, Olga Ilkayeva, Marcus Ståhlman, Philippe St-Pierre, Fredrik Bäckhed, Angelo Tremblay, Phillip J. White, André Marette

Nat Commun. 2021; 12: 3377. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23782-w

PMCID:: PMC8184893

Abstract Article PDF–5.9M

Select item 66432974.

Inhibition of acetyl-CoA carboxylase (ACC) by phosphorylation or by the liver-specific inhibitor, ND-654, suppresses lipogenesis and hepatocellular carcinoma

James S.V. Lally, Sarani Ghoshal, Danielle K. DePeralta, Omeed Moaven, Lan Wei, Ricard Masia, Derek J. Erstad, Naoto Fujiwara, Vivian Leong, Vanessa P. Houde, Alexander E. Anagnostopoulos, Alice Wang, Lindsay A. Broadfield, Rebecca J. Ford, Robert A. Foster, Jamie Bates, Hailing Sun, Ting Wang, Henry Liu, Adrian S. Ray, Asish K. Saha, Jeremy Greenwood, Sathesh Bhat, Geraldine Harriman, Wenyan Miao, Jennifer L. Rocnik, William F. Westlin, Paola Muti, Theodoros Tsakiridis, H. James Harwood, Jr, Rosana Kapeller, Yujin Hoshida, Kenneth K. Tanabe, Gregory R. Steinberg, Bryan C. Fuchs

Cell Metab. Author manuscript; available in PMC 2020 Jan 8.

Published in final edited form as: Cell Metab. 2019 Jan 8; 29(1): 174–182.e5. Published online 2018 Sep 20. doi: 10.1016/j.cmet.2018.08.020

PMCID:: PMC6643297

Abstract Article PDF–1.1M

Select item 52334425.

Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1

Brennan K. Smith, Rebecca J. Ford, Eric M. Desjardins, Alex E. Green, Meghan C. Hughes, Vanessa P. Houde, Emily A. Day, Katarina Marcinko, Justin D. Crane, Emilio P. Mottillo, Christopher G.R. Perry, Bruce E. Kemp, Mark A. Tarnopolsky, Gregory R. Steinberg

Diabetes. Author manuscript; available in PMC 2017 Jan 12.

Published in final edited form as: Diabetes. 2016 Nov; 65(11): 3352–3361. Published online 2016 Aug 23. doi: 10.2337/db16-0564

PMCID:: PMC5233442

Abstract Article PDF–980K

Select item 38983226.

Investigation of LKB1 Ser⁴³¹ phosphorylation and Cys⁴³³ farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity

Vanessa P. Houde, Maria Stella Ritorto, Robert Gourlay, Joby Varghese, Paul Davies, Natalia Shpiro, Kei Sakamoto, Dario R. Alessi

Biochem J. 2014 Feb 15; 458(Pt 1): 41–56. Prepublished online 2013 Dec 3. Published online 2014 Jan 20. doi: 10.1042/BJ20131324

PMCID:: PMC3898322

Abstract Article PDF–2.3M

Select item 33518187.

Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion

Pierre-Gilles Blanchard, William T. Festuccia, Vanessa P. Houde, Philippe St-Pierre, Sophie Brûlé, Véronique Turcotte, Marie Côté, Kerstin Bellmann, André Marette, Yves Deshaies

J Lipid Res. 2012 Jun; 53(6): 1117–1125. doi: 10.1194/jlr.M021485

PMCID:: PMC3351818

Abstract Article PDF–665K

Select item 31298938.

Conservation of Na⁺ vs. K⁺ by the rat cortical collecting duct

Gustavo Frindt, Véronique Houde, Lawrence G. Palmer

Am J Physiol Renal Physiol. 2011 Jul; 301(1): F14–F20. Published online 2011 Mar 30. doi: 10.1152/ajprenal.00705.2010

PMCID:: PMC3129893

Abstract Article

Select item 111438469.

Assessing Credibility: Quality Criteria for Patients, Caregivers, and the Public in Online Health Information—A Qualitative Study

Lubna Daraz, Cicek Dogu, Virginie Houde, Sheila Bouseh, Knondoker G Morshed

J Patient Exp. 2024; 11: 23743735241259440. Published online 2024 May 31. doi: 10.1177/23743735241259440

PMCID:: PMC11143846

Abstract Article PDF–270K

Select item 1101332510.

Fluorocarbon Plasma-Polymerized Layer Increases the Release Time of Silver Ions and the Antibacterial Activity of Silver-Based Coatings

Linda Bonilla-Gameros, Pascale Chevallier, Xavier Delvaux, L. Astrid Yáñez-Hernández, Laurent Houssiau, Xavier Minne, Vanessa P. Houde, Andranik Sarkissian, Diego Mantovani

Nanomaterials (Basel) 2024 Apr; 14(7): 609. Published online 2024 Mar 29. doi: 10.3390/nano14070609

PMCID:: PMC11013325

Abstract Article PDF–5.7M

Select item 1084742911.

Rebaudioside D decreases adiposity and hepatic lipid accumulation in a mouse model of obesity

Arianne Morissette, Alice de Wouters d’Oplinter, Diana Majolli Andre, Marilou Lavoie, Bruno Marcotte, Thibault V. Varin, Jocelyn Trottier, Geneviève Pilon, Martin Pelletier, Patrice D. Cani, Olivier Barbier, Vanessa P. Houde, André Marette

Sci Rep. 2024; 14: 3077. Published online 2024 Feb 6. doi: 10.1038/s41598-024-53587-y

PMCID:: PMC10847429

Abstract Article PDF–2.2M

Select item 1030963612.

Porphyromonas gingivalis under palmitate-induced obesogenic microenvironment modulates the inflammatory transcriptional signature of macrophage-like cells

Xavier Minne, Joanna Mbuya Malaïka Mutombo, Fatiha Chandad, Roberto D. Fanganiello, Vanessa P. Houde

PLoS One. 2023; 18(6): e0288009. Published online 2023 Jun 29. doi: 10.1371/journal.pone.0288009

PMCID:: PMC10309636

Abstract Article PDF–2.2M

Select item 1021886113.

Multi-Omics Data Integration Reveals Key Variables Contributing to Subgingival Microbiome Dysbiosis-Induced Inflammatory Response in a Hyperglycemic Microenvironment

Sarah Lafleur, Antoine Bodein, Joanna Mbuya Malaïka Mutombo, Alban Mathieu, Charles Joly Beauparlant, Xavier Minne, Fatiha Chandad, Arnaud Droit, Vanessa P. Houde

Int J Mol Sci. 2023 May; 24(10): 8832. Published online 2023 May 16. doi: 10.3390/ijms24108832

PMCID:: PMC10218861

Abstract Article PDF–3.8M

Select item 858427614.

The Concentration of Organic Acids in Cranberry Juice Modulates the Gut Microbiota in Mice

Valentine Renaud, Vanessa P. Houde, Geneviève Pilon, Thibault V. Varin, Cyril Roblet, André Marette, Yvan Boutin, Laurent Bazinet

Int J Mol Sci. 2021 Nov; 22(21): 11537. Published online 2021 Oct 26. doi: 10.3390/ijms222111537

PMCID:: PMC8584276

Abstract Article PDF–3.5M

Select item 769061615.

Animal and Cellular Studies Demonstrate Some of the Beneficial Impacts of Herring Milt Hydrolysates on Obesity-Induced Glucose Intolerance and Inflammation

Rachel Durand, Adia Ouellette, Vanessa P. Houde, Frédéric Guénard, Thibaut V. Varin, Bruno Marcotte, Geneviève Pilon, Erwann Fraboulet, Marie-Claude Vohl, André Marette, Laurent Bazinet

Nutrients. 2020 Nov; 12(11): 3235. Published online 2020 Oct 22. doi: 10.3390/nu12113235

PMCID:: PMC7690616

Abstract Article PDF–1.8M

Select item 669070916.

Inhibition of mitochondrial complex 1 by the S6K1 inhibitor PF-4708671 partly contributes to its glucose metabolic effects in muscle and liver cells

Michael Shum, Vanessa P. Houde, Vicky Bellemare, Rafael Junges Moreira, Kerstin Bellmann, Philippe St-Pierre, Benoit Viollet, Marc Foretz, André Marette

J Biol Chem. 2019 Aug 9; 294(32): 12250–12260. Published online 2019 Jun 26. doi: 10.1074/jbc.RA119.008488

PMCID:: PMC6690709

Abstract Article PDF–3.6M

Select item 657458117.

Dietary Proteins Relevant to Human Consumption Impact the Development of Obesity and Type 2 Diabetes in Association with Major Changes in the Gut Microbiota in a Mouse Model (OR27-03-19)

Noëmie Daniel, Béatrice Choi, Vanessa Houde, Thibault Varin, Cecile Vors, Philippe St-Pierre, André Marette

Curr Dev Nutr. 2019 Jun; 3(Suppl 1): nzz046.OR27-03-19. Published online 2019 Jun 13. doi: 10.1093/cdn/nzz046.OR27-03-19

PMCID:: PMC6574581

Abstract PDF–46K

Select item 557933218.

AMPK β1 reduces tumor progression and improves survival in p53 null mice

Vanessa P. Houde, Sara Donzelli, Andrea Sacconi, Sandra Galic, Joanne A. Hammill, Jonathan L. Bramson, Robert A. Foster, Theodoros Tsakiridis, Bruce E. Kemp, Giuseppe Grasso, Giovanni Blandino, Paola Muti, Gregory R. Steinberg

Mol Oncol. 2017 Sep; 11(9): 1143–1155. Published online 2017 Jun 28. doi: 10.1002/1878-0261.12079

PMCID:: PMC5579332

Abstract Article PDF–773K

Select item 503468419.

The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration

Linda A. Villani, Brennan K. Smith, Katarina Marcinko, Rebecca J. Ford, Lindsay A. Broadfield, Alex E. Green, Vanessa P. Houde, Paola Muti, Theodoros Tsakiridis, Gregory R. Steinberg

Mol Metab. 2016 Oct; 5(10): 1048–1056. Published online 2016 Aug 26. doi: 10.1016/j.molmet.2016.08.014

PMCID:: PMC5034684

Abstract Article PDF–1.8M

Select item 488932720.

The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids

Gerta Hoxhaj, Edward Caddye, Ayaz Najafov, Vanessa P Houde, Catherine Johnson, Kumara Dissanayake, Rachel Toth, David G Campbell, Alan R Prescott, Carol MacKintosh

eLife. 2016; 5: e12278. Published online 2016 Apr 22. doi: 10.7554/eLife.12278

PMCID:: PMC4889327

Abstract Article PDF–2.6M

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