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Select item 63655381.

The Amazon rain forest plant Uncaria tomentosa (cat’s claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles

Alan D. Snow, Gerardo M. Castillo, Beth P. Nguyen, Paula Y. Choi, Joel A. Cummings, Judy Cam, Qubai Hu, Thomas Lake, Weihong Pan, Abba J. Kastin, Daniel A. Kirschner, Steven G. Wood, Edward Rockenstein, Eliezer Masliah, Stephen Lorimer, Rudolph E. Tanzi, Lesley Larsen

Sci Rep. 2019; 9: 561. Published online 2019 Feb 6. doi: 10.1038/s41598-019-38645-0

PMCID:: PMC6365538

Abstract Article PDF–5.4M

Select item 78848372.

In vitro comparison of major memory-support dietary supplements for their effectiveness in reduction/inhibition of beta-amyloid protein fibrils and tau protein tangles: key primary targets for memory loss

Alan D. Snow, Joel A. Cummings, Rudolph E. Tanzi, Thomas Lake

Sci Rep. 2021; 11: 3001. Published online 2021 Feb 15. doi: 10.1038/s41598-020-79275-1

PMCID:: PMC7884837

Abstract Article PDF–7.5M

Select item 101585013.

Identification of PXR Activators from Uncaria Rhynchophylla (Gou Teng) and Uncaria Tomentosa (Cat’s Claw)

Saifei Lei, Jie Lu, Anqi Cheng, Zahir Hussain, Kevin Tidgewell, Junjie Zhu, Xiaochao Ma

Drug Metab Dispos. 2023 May; 51(5): 629–636. Published online 2023 May. doi: 10.1124/dmd.122.001234

PMCID:: PMC10158501

Abstract Article PDF–1.1M

Select item 76573994.

Uncaria tomentosa (cat’s claw): a promising herbal medicine against SARS-CoV-2/ACE-2 junction and SARS-CoV-2 spike protein based on molecular modeling

Andres F. Yepes-Pérez, Oscar Herrera-Calderon, Jorge Quintero-Saumeth

J Biomol Struct Dyn. 2020 : 1–17. Published online 2020 Oct 29. doi: 10.1080/07391102.2020.1837676

PMCID:: PMC7657399

Abstract Article PDF–4.1M

Select item 109744755.

Antiviral and Virucidal Activities of Uncaria tomentosa (Cat’s Claw) against the Chikungunya Virus

Raquel Curtinhas de Lima, Ligia Maria Marino Valente, Débora Familiar Macedo, Luzia Maria de-Oliveira-Pinto, Flavia Barreto dos Santos, José Luiz Mazzei, Antonio Carlos Siani, Priscila Conrado Guerra Nunes, Elzinandes Leal de Azeredo

Viruses. 2024 Mar; 16(3): 369. Published online 2024 Feb 27. doi: 10.3390/v16030369

PMCID:: PMC10974475

Abstract Article PDF–4.5M

Select item 75324116.

Investigating Potential Inhibitory Effect of Uncaria tomentosa (Cat's Claw) against the Main Protease 3CL^pro of SARS-CoV-2 by Molecular Modeling

Andres F. Yepes-Pérez, Oscar Herrera-Calderon, José-Emilio Sánchez-Aparicio, Laura Tiessler-Sala, Jean-Didier Maréchal, Wilson Cardona-G

Evid Based Complement Alternat Med. 2020; 2020: 4932572. Published online 2020 Sep 30. doi: 10.1155/2020/4932572

PMCID:: PMC7532411

Abstract Article PDF–3.6M

Select item 79224717.

Treatment with Uncaria tomentosa Promotes Apoptosis in B16-BL6 Mouse Melanoma Cells and Inhibits the Growth of B16-BL6 Tumours

Ali Zari, Hajer Alfarteesh, Carly Buckner, Robert Lafrenie

Molecules. 2021 Feb; 26(4): 1066. Published online 2021 Feb 18. doi: 10.3390/molecules26041066

PMCID:: PMC7922471

Abstract Article PDF–3.7M

Select item 614508.

Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis

Mark JS Miller, Fausto M Angeles, Brian K Reuter, Paul Bobrowski, Manuel Sandoval

BMC Complement Altern Med. 2001; 1: 11. Published online 2001 Dec 10. doi: 10.1186/1472-6882-1-11

PMCID:: PMC61450

Abstract Article PDF–1.0M

Select item 61304989.

In vitro synergism of a water insoluble fraction of Uncaria tomentosa combined with fluconazole and terbinafine against resistant non-Candida albicans isolates

Renata Cougo Moraes, Anderson Ramos Carvalho, Aline Jacobi Dalla Lana, Samuel Kaiser, Bruna Pippi, Alexandre Meneghello Fuentefria, George González Ortega

Pharm Biol. 2017; 55(1): 406–415. Published online 2016 Dec 8. doi: 10.1080/13880209.2016.1242631

PMCID:: PMC6130498

Abstract Article PDF–1.1M

Select item 633225710.

Phenolic Assesment of Uncaria tomentosa L. (Cat’s Claw): Leaves, Stem, Bark and Wood Extracts

Mirtha Navarro Hoyos, Fernando Sánchez-Patán, Renato Murillo Masis, Pedro J. Martín-Álvarez, William Zamora Ramirez, Maria J. Monagas, Begoña Bartolomé

Molecules. 2015 Dec; 20(12): 22703–22717. Published online 2015 Dec 18. doi: 10.3390/molecules201219875

PMCID:: PMC6332257

Abstract Article PDF–2.3M

Select item 792966511.

The Hydroalcoholic Extract of Uncaria tomentosa (Cat's Claw) Inhibits the Infection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) In Vitro

Andres F. Yepes-Perez, Oscar Herrera-Calderón, Cristian A. Oliveros, Lizdany Flórez-Álvarez, María I. Zapata-Cardona, Lina Yepes, Wbeimar Aguilar-Jimenez, María T. Rugeles, Wildeman Zapata

Evid Based Complement Alternat Med. 2021; 2021: 6679761. Published online 2021 Feb 24. doi: 10.1155/2021/6679761

PMCID:: PMC7929665

Abstract Article PDF–1.3M

Select item 668329012.

Unnatural spirocyclic oxindole alkaloids biosynthesis in Uncaria guianensis

Adriana A. Lopes, Bianca Chioca, Bruno Musquiari, Eduardo J. Crevelin, Suzelei de C. França, Maria Fatima das G. Fernandes da Silva, Ana Maria S. Pereira

Sci Rep. 2019; 9: 11349. Published online 2019 Aug 5. doi: 10.1038/s41598-019-47706-3

PMCID:: PMC6683290

Abstract Article PDF–1.8M

Select item 1117651113.

Anti-inflammatory and/or immunomodulatory activities of Uncaria tomentosa (cat’s claw) extracts: A systematic review and meta-analysis of in vivo studies

Gustavo Marin Arado, Pedro de Padua G. Amatto, Mozart Marins, Elen Sanchez Rizzi, Suzelei de Castro França, Juliana da Silva Coppede, Fábio Carmona, Ana Maria Soares Pereira

Front Pharmacol. 2024; 15: 1378408. Published online 2024 May 31. doi: 10.3389/fphar.2024.1378408

PMCID:: PMC11176511

Abstract Article PDF–1.8M

Select item 615471114.

Uncaria tomentosa Leaves Decoction Modulates Differently ROS Production in Cancer and Normal Cells, and Effects Cisplatin Cytotoxicity

Anita Kośmider, Edyta Czepielewska, Mieczysław Kuraś, Krzysztof Gulewicz, Wioleta Pietrzak, Renata Nowak, Grażyna Nowicka

Molecules. 2017 Apr; 22(4): 620. Published online 2017 Apr 12. doi: 10.3390/molecules22040620

PMCID:: PMC6154711

Abstract Article PDF–5.5M

Select item 605464515.

Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLD

Layanne C. C. Araujo, Karla B. Feitosa, Gilson M. Murata, Isadora C. Furigo, Simone A. Teixeira, Camila F. Lucena, Luciene M. Ribeiro, Marcelo N. Muscará, Soraia K. P. Costa, José Donato, Jr, Silvana Bordin, Rui Curi, Carla R. O. Carvalho

Sci Rep. 2018; 8: 11013. Published online 2018 Jul 20. doi: 10.1038/s41598-018-29044-y

PMCID:: PMC6054645

Abstract Article PDF–3.7M

Select item 890591216.

GlucoMedix®, an extract of Stevia rebaudiana and Uncaria tomentosa, reduces hyperglycemia, hyperlipidemia, and hypertension in rat models without toxicity: a treatment for metabolic syndrome

León F. Villegas Vílchez, Julio Hidalgo Ascencios, Thomas P. Dooley

BMC Complement Med Ther. 2022; 22: 62. Published online 2022 Mar 8. doi: 10.1186/s12906-022-03538-9

Correction in:: BMC Complement Med Ther. 2022; 22: 230.

PMCID:: PMC8905912

Abstract Article PDF–1.7M

Select item 1012423417.

A Comprehensive Review of Herbal Supplements Used for Persistent Symptoms Attributed to Lyme Disease

Allison Thompson, Lauren M. Hynicka, Kalpana D. Shere-Wolfe

Integr Med (Encinitas) 2023 Mar; 22(1): 30–38.

PMCID:: PMC10124234

Abstract Article PDF–290K

Select item 1020915718.

Chloroplast genome characterization of Uncaria guianensis and Uncaria tomentosa and evolutive dynamics of the Cinchonoideae subfamily

Andrezza Arantes Castro, Rhewter Nunes, Larissa Resende Carvalho, Cíntia Pelegrineti Targueta, Ramilla dos Santos Braga-Ferreira, Amanda Alves de Melo-Ximenes, Leonardo Carlos Jeronimo Corvalán, Bianca Waleria Bertoni, Ana Maria Soares Pereira, Mariana Pires de Campos Telles

Sci Rep. 2023; 13: 8390. Published online 2023 May 24. doi: 10.1038/s41598-023-34334-1

PMCID:: PMC10209157

Abstract Article PDF–4.0M

Select item 633711619.

Herb–Drug Interaction Potential of Anti-Borreliae Effective Extracts from Uncaria tomentosa (Samento) and Otoba parvifolia (Banderol) Assessed In Vitro

Johanna Weiss

Molecules. 2019 Jan; 24(1): 137. Published online 2018 Dec 31. doi: 10.3390/molecules24010137

PMCID:: PMC6337116

Abstract Article PDF–1.6M

Select item 447442420.

Effect of Uncaria tomentosa extract on purinergic enzyme activities in lymphocytes of rats submitted to experimental adjuvant arthritis model

Lívia G. Castilhos, João F. P. Rezer, Jader B. Ruchel, Maria Luiza Thorstenberg, Jeandre A. dos S. Jaques, Josiane B. Schlemmer, Pedro H. Doleski, Mateus F. Rossato, Mariane A. da Silva, Emerson André Casalli, Ritiel Corrêa da Cruz, Juliano Ferreira, Margareth L. Athayde, Jamile F. Gonçalves, Daniela B. R. Leal

BMC Complement Altern Med. 2015; 15: 189. Published online 2015 Jun 20. doi: 10.1186/s12906-015-0694-4

PMCID:: PMC4474424

Abstract Article PDF–664K

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