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Select item 109364221.

Endogenous IL-27 during toxoplasmosis limits early monocyte responses and their inflammatory activation by pathological T cells

Daniel L. Aldridge, Devapregasan Moodley, Jeongho Park, Anthony T. Phan, Matthew Rausch, Kerry F. White, Yue Ren, Karin Golin, Enrico Radaelli, Ross Kedl, Pamela M. Holland, Jonathan Hill, Christopher A. Hunter

mBio. 2024 Mar; 15(3): e00083-24. Published online 2024 Feb 20. doi: 10.1128/mbio.00083-24

PMCID:: PMC10936422

Article PDF–4.0M

Select item 107735352.

IL-27 increases energy storage in white adipocytes by enhancing glucose uptake and fatty acid esterification

Chiara Scaffidi, Annie Srdic, Daniel Konrad, Stephan Wueest

Adipocyte. 2023; 12(1): 2276346. Published online 2023 Nov 10. doi: 10.1080/21623945.2023.2276346

PMCID:: PMC10773535

Article PDF–2.0M

Select item 107016053.

IL‐27 produced during acute malaria infection regulates Plasmodium‐specific memory CD4⁺ T cells

Maria Lourdes Macalinao, Shin‐Ichi Inoue, Sanjaadorj Tsogtsaikhan, Hirotaka Matsumoto, Ganchimeg Bayarsaikhan, Jiun‐Yu Jian, Kazumi Kimura, Yoshiaki Yasumizu, Tsuyoshi Inoue, Hiroki Yoshida, Julius Hafalla, Daisuke Kimura, Katsuyuki Yui

EMBO Mol Med. 2023 Dec; 15(12): e17713. Published online 2023 Oct 19. doi: 10.15252/emmm.202317713

PMCID:: PMC10701605

Article PDF–3.3M

Select item 100306514.

Inactivation of interleukin-30 in colon cancer stem cells via CRISPR/Cas9 genome editing inhibits their oncogenicity and improves host survival

Luigi D'Antonio, Cristiano Fieni, Stefania Livia Ciummo, Simone Vespa, Lavinia Lotti, Carlo Sorrentino, Emma Di Carlo

J Immunother Cancer. 2023; 11(3): e006056. Published online 2023 Mar 16. doi: 10.1136/jitc-2022-006056

PMCID:: PMC10030651

Article PDF–26M

Select item 99852665.

IL-27 induces autophagy through regulation of the DNMT1/lncRNA MEG3/ERK/p38 axis to reduce pulmonary fibrosis

Li Ting, Yingying Feng, Ying Zhou, Zhongkai Tong, Zhaoxing Dong

Respir Res. 2023; 24: 67. Published online 2023 Mar 3. doi: 10.1186/s12931-023-02373-x

PMCID:: PMC9985266

Article PDF–9.9M

Select item 96744206.

Interleukin-27 Ameliorates Atherosclerosis in ApoE^−/− Mice through Regulatory T Cell Augmentation and Dendritic Cell Tolerance

Wenbin Xu, Ruirui Zhu, Zhengfeng Zhu, Kunwu Yu, Yue Wang, Yan Ding, Jian Yu, Hongxia Tang, Qiutang Zeng, Yucheng Zhong

Mediators Inflamm. 2022; 2022: 2054879. Published online 2022 Nov 11. doi: 10.1155/2022/2054879

PMCID:: PMC9674420

Article PDF–2.8M

Select item 94777977.

Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease

Huanle Gong, Shoubao Ma, Jia Chen, Bingyu Yang, Shuangzhu Liu, Xin Liu, Jingjing Han, Xiaojin Wu, Lei Lei, Zhinan Yin, Hongjian Sun, Di Yu, Haiyan Liu, Yang Xu, Depei Wu

Signal Transduct Target Ther. 2022; 7: 319. Published online 2022 Sep 16. doi: 10.1038/s41392-022-01147-z

PMCID:: PMC9477797

Article PDF–5.0M

Select item 90225688.

Interleukin-27 (IL-27) Promotes Chlamydial Infection in the Female Genital Tract

Yujie Zhao, Zhi Huo, Zengzi Zhou, Christian Cervantes, Jianlin Chen, Zhenming Xu, Guangming Zhong

Infect Immun. 2022 Apr; 90(4): e00651-21. Published online 2022 Mar 8. doi: 10.1128/iai.00651-21

PMCID:: PMC9022568

Article PDF–844K

Select item 87841169.

B cell–derived IL-27 promotes control of persistent LCMV infection

Isaraphorn Pratumchai, Jaroslav Zak, Zhe Huang, Booki Min, Michael B. A. Oldstone, John R. Teijaro

Proc Natl Acad Sci U S A. 2022 Jan 18; 119(3): e2116741119. Published online 2022 Jan 12. doi: 10.1073/pnas.2116741119

PMCID:: PMC8784116

Article PDF–2.5M

Select item 848067110.

Gut epithelial IL-27 confers intestinal immunity through the induction of intraepithelial lymphocytes

Chia-Hao Lin, Mei-Chi Chen, Ling-Li Lin, David A. Christian, Booki Min, Christopher A. Hunter, Li-Fan Lu

J Exp Med. 2021 Nov 1; 218(11): e20210021. Published online 2021 Sep 23. doi: 10.1084/jem.20210021

PMCID:: PMC8480671

Article PDF–3.1M

Select item 743160311.

IL-27 Regulated CD4⁺IL-10⁺ T Cells in Experimental Sjögren Syndrome

Jingjing Qi, Zhuoya Zhang, Xiaojun Tang, Wenchao Li, Weiwei Chen, Genhong Yao

Front Immunol. 2020; 11: 1699. Published online 2020 Aug 11. doi: 10.3389/fimmu.2020.01699

PMCID:: PMC7431603

Article PDF–6.6M

Select item 719007912.

IL-27 signaling deficiency develops Th17-enhanced Th2-dominant inflammation in murine allergic conjunctivitis model

Xin Chen, Ruzhi Deng, Wei Chi, Xia Hua, Fan Lu, Fang Bian, Ning Gao, Zhijie Li, Stephen C. Pflugfelder, Cintia S. de Paiva, De-Quan Li

Allergy. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Allergy. 2019 May; 74(5): 910–921. Published online 2019 Jan 4. doi: 10.1111/all.13691

PMCID:: PMC7190079

Article PDF–3.6M

Select item 698106913.

cDC1 IL-27p28 production predicts vaccine-elicited CD8+ T cell memory and protective immunity

Augustus M. Kilgore, Nathan D. Pennock, Ross M. Kedl

J Immunol. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: J Immunol. 2020 Feb 1; 204(3): 510–517. Published online 2019 Dec 23. doi: 10.4049/jimmunol.1901357

PMCID:: PMC6981069

Article PDF–1.6M

Select item 668398414.

IL-27 promotes the expansion of self-renewing CD8⁺ T cells in persistent viral infection

Zhe Huang, Jaroslav Zak, Isaraphorn Pratumchai, Namir Shaabani, Vincent F. Vartabedian, Nhan Nguyen, Tuoqi Wu, Changchun Xiao, John R. Teijaro

J Exp Med. 2019 Aug 5; 216(8): 1791–1808. Published online 2019 Jun 4. doi: 10.1084/jem.20190173

PMCID:: PMC6683984

Article PDF–4.2M

Select item 653631715.

Murine myeloid-derived suppressor cells are a source of elevated levels of interleukin-27 in early life and compromise control of bacterial infection

Madeline Gleave Parson, Juanita Grimmett, Jordan K. Vance, Michelle R. Witt, Brittany G. Seman, Travis W. Rawson, Logan Lyda, Christopher Labuda, Joo-Yong Jung, Shelby D. Bradford, Cory M. Robinson

Immunol Cell Biol. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Immunol Cell Biol. 2019 May; 97(5): 445–456. Published online 2019 Feb 8. doi: 10.1111/imcb.12224

PMCID:: PMC6536317

Article PDF–647K

Select item 640122616.

IL-27 attenuates autoimmune neuroinflammation via Treg/Lag3-dependent but IL-10-independent mechanisms in vivo

Dongkyun Kim, Hongnga T. Le, Quang Tam Nguyen, Sohee Kim, Juyeun Lee, Booki Min

J Immunol. Author manuscript; available in PMC 2020 Mar 15.

Published in final edited form as: J Immunol. 2019 Mar 15; 202(6): 1680–1685. Published online 2019 Jan 30. doi: 10.4049/jimmunol.1800898

PMCID:: PMC6401226

Article PDF–906K

Select item 624460917.

Distinct Role of IL-27 in Immature and LPS-Induced Mature Dendritic Cell-Mediated Development of CD4⁺ CD127⁺3G11⁺ Regulatory T Cell Subset

Fang Zhou, Guang-Xian Zhang, Abdolmohamad Rostami

Front Immunol. 2018; 9: 2562. Published online 2018 Nov 13. doi: 10.3389/fimmu.2018.02562

PMCID:: PMC6244609

Article PDF–1.7M

Select item 613083318.

Dyslipidemia promotes germinal center reactions via IL-27

Heeju Ryu, Yeonseok Chung

BMB Rep. 2018 Aug; 51(8): 371–372. Published online 2018 Aug 31. doi: 10.5483/BMBRep.2018.51.8.171

PMCID:: PMC6130833

Article PDF–339K

Select item 577126419.

IL-27p28 Production by XCR1⁺ Dendritic Cells and Monocytes Effectively Predicts Adjuvant-Elicited CD8⁺ T Cell Responses

Augustus M. Kilgore, Seth Welsh, Elizabeth E. Cheney, Alisha Chitrakar, Trevor J. Blain, Benjamin J. Kedl, Chris A. Hunter, Nathan D. Pennock, Ross M. Kedl

Immunohorizons. Author manuscript; available in PMC 2018 Jan 17.

Published in final edited form as: Immunohorizons. 2018 Jan 1; 2(1): 1–11. doi: 10.4049/immunohorizons.1700054