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Antiviral activity against Human immunodeficiency virus 1 clone 4378 harboring integrase E157Q V31I, V32I, S39C, I72V, L101I, K160Q, F181L, V201I, Q216H, A265V mutation transfected in human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Assay data:1 Tested
SummaryPubMed Citation
Antiviral activity against Human immunodeficiency virus 1 clone 8070_2 harboring integrase G140S, Q148H, K14R, L63I, L101I, T112A, G193E, D229E, D279G mutation transfected in human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Antiviral activity against Human immunodeficiency virus 1 clone 8070_1 harboring integrase G140S, Y143H,Q148H and K14R, L101I, T112A, G193E, D229E, D279G mutation in transfected in human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Antiviral activity against Human immunodeficiency virus 1 clone 1556 harboring integrase Y143C, L74M, T97A, S230R, K7R, S17N, R20K, L101I, K111Q, T112K, S119R, T206S, D256E, V259I mutation transfected in human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Antiviral activity against Human immunodeficiency virus 1 clone 4736_10 harboring integrase N155H, V151I, G163R and D6E, S17N, R20K, D25E, S39C, L45V, L101I, T124A, K160T, V201I, K211R, D288N mutation transfected in human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Antiviral activity against Human immunodeficiency virus 1 clone 4736_9 harboring integrase N155H, E92Q H51Y and D6E, S17N, R20K, D25E, S39C, D41H, L45V, L101I, T124A, K160T, V201I,K211R, D288N mutation transfected in human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Antiviral activity against Human immunodeficiency virus 1 clone 4736_4 harboring integrase N155H, E92Q and D6E, S17N, R20K, D25E, S39C, L45V, L101I, T124A, K160T, V201I, K211R, D288N mutation transfected in human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Antiviral activity against Human immunodeficiency virus 1 clone 4736_2 harboring integrase N155H,T97A and D6E, S17N, R20K, D25E, S39C, L45V,L101I, V201I, S119R, T124A, K160T, K211R, D288N mutation transfected into human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Antiviral activity against Human immunodeficiency virus 1 clone 1288 harboring integrase M154L and E11D, V31I, L101I, K160R, F181L,V201I, T206S, D256E mutation transfected into human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
Antiviral activity against Human immunodeficiency virus 1 clone 2253 harboring integrase S17N, V31I, I72V, L101I, T124A, K156N,V201I, I220M, D279G, R284G mutation transfected into human C8166 cells assessed as decrease in compound susceptibility relative to wild-type
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