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Inhibition of GGT1 in human MDA-MB-231 cells assessed as decrease in Rap1A geranylgeranylation at 5 uM after 48 hrs by Western blot method relative to control
Assay data:11 Active, 16 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of recombinant GGT1 (unknown origin) using GGPP as substrate preincubated for 5 mins followed by protein addition measured over 20 mins by fluorescence assay
Assay data:5 Active, 16 Tested
Inhibition of human GGT K562S mutant expressed in baculovirus infected High Five cells assessed as residual activity up to 1 mM using gamma-Glu-PNA as substrate after 5 mins by spectrophotometric method relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of hydrolytic activity of human GGT using 7-(N-gamma-glutamylamino)-4-methylcoumarin as substrate assessed as release of AMC after 10 mins by fluorescence assay
Assay data:9 Tested
Ratio of acivicin to compound for hydrolytic activity of human GGT
Inhibition of hydrolytic activity of human GGT using 7-(N-gamma-glutamylamino)-4-methylcoumarin as substrate assessed as release of AMC at 1 mM after 10 mins by fluorescence assay
Assay data:5 Tested
Irreversible inhibition of hydrolytic activity of human GGT using 7-(N-gamma-glutamylamino)-4-methylcoumarin as substrate assessed as release of AMC at 1 mM after 10 mins by fluorescence assay
Assay data:1 Active, 1 Tested
Inhibition of hydrolytic activity of human GGT using 7-(N-gamma-glutamylamino)-4-methylcoumarin as substrate assessed as release of AMC by fluorescence assay
Inhibition of gamma-glutamyltranspeptidase by colorimetric assay
Assay data:17 Tested
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