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Binding affinity to SARS CoV N-terminal his-tagged Main protease using Dabcyl-KTSAVLQSGFRKME-Edan peptide as substrate by fluorescence based analysis
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Various Assay from Article 10.1021/acs.jmedchem.1c00409: "Perspectives on SARS-CoV-2 Main Protease Inhibitors."
Assay data:473 Active, 1 Activity ≤ 1 nM, 248 Activity ≤ 1 µM, 795 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition Assay from Article 10.1016/j.chembiol.2005.12.008: "Stable benzotriazole esters as mechanism-based inactivators of the severe acute respiratory syndrome 3CL protease."
Assay data:11 Active, 9 Activity ≤ 1 µM, 16 Tested
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