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Items: 1 to 20 of 139

1.

Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate by kinetic fluorescent assay

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
2.

Reversible-uncompetitive inhibition of sEH (unknown origin) by Lineweaver-Burk plot

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
3.

Inhibition of sEH (unknown origin) assessed as 6-methoxy-2-naphthaldehyde formation by fluorometry assay using 40 uM cyano-(6-methoxy-naphthalen-2-yl)-methyl ester as substrate

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
4.

Inhibition of sEH (unknown origin) assessed as 6-methoxy-2-naphthaldehyde formation at 50 uM by fluorometry assay using 40 uM cyano-(6-methoxy-naphthalen-2-yl)-methyl ester as substrate

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
5.

Inhibition of recombinant human sEH expressed in baculovirus infected insect Sf9 cells using CMNPC as substrate assessed as 6-methoxy-2-naphthadehyde level after 10 mins by fluorescence assay

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
AID:
1254243
6.

Mixed-type inhibition of sEH (unknown origin) using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde measured during 30 mins by Lineweaver-Burk plot analysis

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
7.

Non-competitive inhibition of sEH (unknown origin) using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde measured during 30 mins by Lineweaver-Burk plot analysis

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
8.

Mixed-type inhibition of sEH (unknown origin) using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde measured during 30 mins by Dixon plot analysis

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
9.

Non-competitive inhibition of sEH (unknown origin) using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde measured during 30 mins by Dixon plot analysis

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
10.

Inhibition of sEH (unknown origin) using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde measured during 1 hr by fluorescence photometric analysis

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
11.

Inhibition of sEH (unknown origin) using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde at 100 uM measured during 1 hr by fluorescence photometric analysis relative to control

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
12.
13.

Inhibition of recombinant rat soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate reader

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
AID:
1194251
14.

Inhibition of recombinant human soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate reader

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
AID:
1194250
15.

Inhibition of recombinant human sEH using CMNPC substrate by fluoresecent-based assay

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
16.

Inhibition of rat soluble epoxide hydrolase assessed as half-life of enzyme-inhibitor complex by FRET-based ACPU displacement assay

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
17.

Inhibition of rat soluble epoxide hydrolase using [3H]-t-DPPO as a substrate by radiometric assay

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
18.

Inhibition of human recombinant soluble epoxide hydrolase assessed as half-life of enzyme-inhibitor complex by FRET-based ACPU displacement assay

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
19.

Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assay

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
AID:
1186229
20.

Inhibition of human recombinant soluble epoxide hydrolase assessed as conversion of 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid to fluorescent 6-methoxy-naphthaldehyde at 10 uM after 10 mins by fluorescence-based assay

Source:
ChEMBL
Protein Target:
Bifunctional epoxide hydrolase 2; Includes: Cytosolic epoxide hydrolase 2; CEH; Epoxide hydratase; Soluble epoxide hydrolase; SEH; Includes: Lipid-phosphate phosphatase
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