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Items: 1 to 20 of 1452

1.

Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric method

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
2.

Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric method

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
3.

Inhibition of COX2 (unknown origin) at 100 uM using arachidonic acid substrate by colorimetric assay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
4.

Inhibition of COX1 (unknown origin) at 100 uM using arachidonic acid substrate by colorimetric assay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
5.

Inhibition of COX2 (unknown origin) using arachidonic acid substrate by colorimetric assay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
6.

Inhibition of COX1 (unknown origin) using arachidonic acid substrate by colorimetric assay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
7.

Inhibition of COX2 (unknown origin) assessed as PGH2 production at 100 uM by measuring PGH2alpha level by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
8.

Inhibition of COX2 (unknown origin) assessed as PGH2 production at 35 uM by measuring PGH2alpha level by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
9.

Inhibition of COX2 (unknown origin) assessed as PGH2 production at 10 uM by measuring PGH2alpha level by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
10.

Inhibition of COX1 (unknown origin) assessed as PGH2 production at 100 uM by measuring PGH2alpha level by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
11.

Inhibition of COX1 (unknown origin) assessed as PGH2 production at 35 uM by measuring PGH2alpha level by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
12.

Inhibition of COX1 (unknown origin) assessed as PGH2 production at 10 uM by measuring PGH2alpha level by enzyme immunoassay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
13.

Inhibition of human recombinant COX-2 using arachidonic acid after 15 mins by fluorescence based assay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
14.

Inhibition of ovine COX-1 using arachidonic acid after 15 mins by fluorescence based assay

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
15.

Inhibition of COX2 in differentiated human THP1 cells assessed as induction of LPS-induced COX2 gene expression at 50 ug/ml preincubated for 1 hr followed by LPS induction measured after 3 hrs by real-time PCR analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
16.

Inhibition of sheep placental cotyledons COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition after 20 mins by competitive PGE2 EIA method

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
17.

Inhibition of sheep placental cotyledons COX-2 using arachidonic acid as substrate at 50 ug/ml preincubated for 5 mins followed by substrate addition after 20 mins by competitive PGE2 EIA method

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
18.

Inhibition of rat seminal vesicles COX-1 using arachidonic acid as substrate at 50 ug/ml preincubated for 5 mins followed by substrate addition after 20 mins by competitive PGE2 EIA method

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
19.

Inhibition of COX-1 in human platelet using arachidonic acid as substrate assessed as formation of 12-HHT preincubated for 10 mins followed by substrate addition measured after 5 mins by HPLC analysis

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
20.

Competitive inhibition of ovine COX2 using arachidonic acid substrate by Ellman's spectrophotometric assay based Lineweaver-Burk double reciprocal plot

Source:
ChEMBL
Protein Target:
Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
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