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Items: 1 to 20 of 70

1.

Inhibition of TrxR in human HeLa cells assessed as depletion of cellular thiol after 48 hrs

Source:
ChEMBL
Protein Targets:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; ...
Total:
3
2.

Inhibition of TrxR in human HeLa cells after 48 hrs by TRFS-green based fluorescence microscopy

Source:
ChEMBL
Protein Targets:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; ...
Total:
3
3.

Inhibition of TrxR in human HeLa cells after 48 hrs by end point reduction assay

Source:
ChEMBL
Protein Targets:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; ...
Total:
3
4.

In vitro inhibition of TrxR U498C mutant (unknown origin) up to 40 uM after 2 hrs incubation by microplate reader

Source:
ChEMBL
Protein Targets:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; ...
Total:
3
5.

In vitro inhibition of NADPH-reduced TrxR (unknown origin) after 2 hrs incubation by microplate reader

Source:
ChEMBL
Protein Targets:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; ...
Total:
3
6.

Inhibition of oxidized human TXR1 reductase activity by insulin reduction assay

Source:
ChEMBL
Protein Target:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1
7.

Inhibition of TrxR antioxidant enzyme activity in human A375 cells at 2 ug/mL incubated for 6 hrs followed by irradiation with 8 Gy X-ray at 37 degC for 12 hrs by insulin reduction assay

Source:
ChEMBL
Protein Targets:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; ...
Total:
3
8.

Inhibition of TrxR antioxidant enzyme activity in human A375 cells at 2 ug/mL after 18 hrs by insulin reduction assay

Source:
ChEMBL
Protein Targets:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; ...
Total:
3
10.

Activity of partially purified rat Thioredoxin reductase assessed as NADPH oxidation after 10 mins by spectrophotometry

Source:
ChEMBL
Protein Target:
Thioredoxin reductase 1, cytoplasmic; TR; NADPH-dependent thioredoxin reductase; Thioredoxin reductase TR1
11.

Activity of partially purified rat Thioredoxin reductase assessed as NADPH oxidation after 10 mins by spectrophotometry relative to ebselen

Source:
ChEMBL
Protein Target:
Thioredoxin reductase 1, cytoplasmic; TR; NADPH-dependent thioredoxin reductase; Thioredoxin reductase TR1
12.

Activity of partially purified rat Thioredoxin reductase assessed as 5 umol/L AuCl3-mediated inhibition of NADPH oxidation by spectrophotometry

Source:
ChEMBL
Protein Target:
Thioredoxin reductase 1, cytoplasmic; TR; NADPH-dependent thioredoxin reductase; Thioredoxin reductase TR1
13.

Thioredoxin reductase 1 inhibitor

Source:
ChEMBL
Protein Target:
Thioredoxin reductase 1, cytoplasmic; TR; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1
14.

Non-competitive inhibition of rat TrxR1

Source:
ChEMBL
Protein Target:
Thioredoxin reductase 1, cytoplasmic; TR; NADPH-dependent thioredoxin reductase; Thioredoxin reductase TR1
15.

Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay

Source:
ChEMBL
Protein Target:
Thioredoxin reductase 1, cytoplasmic; TR; NADPH-dependent thioredoxin reductase; Thioredoxin reductase TR1
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