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Items: 1 to 20 of 27

1.

Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]choline by [3H]choline uptake assay

Source:
ChEMBL
Protein Target:
High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7
2.

Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H]choline by [3H]choline uptake assay

Source:
ChEMBL
Protein Target:
High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7
3.

Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity at 5 uM in presence of 10 uM [3H]choline by [3H]choline uptake assay

Source:
ChEMBL
Protein Target:
High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7
4.

Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity at 5 uM in presence of 100 nM [3H]choline by [3H]choline uptake assay

Source:
ChEMBL
Protein Target:
High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7
5.

Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assay

Source:
ChEMBL
Protein Target:
High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7
6.

Confirmed inhibitors of the Choline Transporter (CHT)

Source:
Meiler Lab, Vanderbilt University
Protein Target:
high affinity choline transporter 1 isoform a [Homo sapiens]
7.

Discovery and structure-activity relationship of a novel choline transporter inhibitor: ML352

Source:
Vanderbilt Specialized Chemistry Center
Protein Target:
high affinity choline transporter 1 isoform a [Homo sapiens]
8.
9.

Discovery and structure-activity relationship of a novel choline transporter inhibitor

Source:
Vanderbilt Specialized Chemistry Center
Protein Target:
high affinity choline transporter 1 isoform a [Homo sapiens]
10.
11.
12.
13.

Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC

Source:
Johns Hopkins Ion Channel Center
Protein Target:
high affinity choline transporter 1 isoform a [Homo sapiens]
14.

JHICC_CHT_Inh_3H uptake_CRC

Source:
Johns Hopkins Ion Channel Center
Protein Target:
high affinity choline transporter 1 isoform a [Homo sapiens]
15.

Dose responses of compounds that inhibit the Choline Transporter (CHT) - 10 point CRC

Source:
Johns Hopkins Ion Channel Center
Protein Target:
high affinity choline transporter 1 isoform a [Homo sapiens]
16.

Binding affinity to human choline transporter (CHT1) by radioligand displacement assay

Source:
ChEMBL
Protein Target:
High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7
17.

Dose responses of compounds that inhibit the Choline Transporter (CHT) - 5 point CRC

Source:
Johns Hopkins Ion Channel Center
Protein Target:
high affinity choline transporter 1 isoform a [Homo sapiens]
18.

Confirmatory screen for compounds that activate the Choline Transporter (CHT)

Source:
Johns Hopkins Ion Channel Center
Protein Target:
high affinity choline transporter 1 isoform a [Homo sapiens]
19.

Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome

Source:
ChEMBL
Protein Target:
High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7
20.

Binding affinity to rat choline transporter 1

Source:
ChEMBL
Protein Target:
High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7
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