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Items: 1 to 20 of 187

3.

Prodrug conversion assessed as recombinant human caspase-3-mediated compound 8 formation at 100 uM after 60 mins by HPLC analysis in presence of caspase-3 inhibitor Ac-DEVD-CHO

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
5.

Activation of procaspase-3 (unknown origin) using Ac-DEVD-pNa as substrate at 10 uM after 2 hrs by spectrophotometry

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
6.

Binding affinity to procaspase-3 (unknown origin)

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
7.

Inhibition of recombinant human caspase-3 activity using Ac-DEVD-AMC as substrate preincubated for 10 mins by fluorescence assay

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
8.

Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic product

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
9.

Inhibition of recombinant human caspase 3 using DEVDAA substrate at up to 5 uM after 3 hrs

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
10.

Inhibition of recombinant human caspase 3 using DEVDAA substrate at up to 20 uM after 3 hrs

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
11.

Ratio of PAC1 EC50 to compound EC50 for procaspase 3 activity (unknown origin)

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
12.

Induction of procaspase 3 activity (unknown origin) using Ac-DEVD-pNa as substrate after 2 hrs

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
13.

Inhibition of caspase 3 (unknown origin) at 30 uM

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
14.

Inhibition of human caspase-3 using fluorogenic peptide as substrate

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
15.

Inhibition of human caspase-3 using fluorogenic peptide as substrate at 31 uM

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
16.

Inhibition of human recombinant caspase-3 using Ac-LDEVD-AMC as substrate after 10 mins by fluorescence assay

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
17.

Inhibition of caspase-3 (unknown origin)

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
18.

Inhibition of recombinant human caspase-3 expressed in Escherichia coli using Ac-DEVD-AMC as substrate preincubated for 30 mins before substrate addition measured after 2 hrs

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
AID:
1077357
19.

Induction of caspase3 (unknown origin) cleavage after 4 hrs by Western blotting analysis in presence of DMEM

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
20.

Induction of caspase3 (unknown origin) cleavage after 4 hrs by Western blotting analysis in presence of nutrient-deprived medium

Source:
ChEMBL
Protein Target:
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12
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