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Items: 1 to 20 of 94

1.

Antagonist activity against FPR2 (unknown origin) pre-treated for 5 mins before addition of Wpep by Fluo4 florescence based intracellular Ca2+ mobilization assay

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
2.

Agonist activity at FPR2 (unknown origin) by Fluo4 florescence based intracellular Ca2+ mobilization assay

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
3.

Antagonist activity against human FPR2 expressed in rat RBL-2H3 cells pre-treated for 15 mins before addition of WKYMVm or C1 by intracellular Ca2+ mobilization assay

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
4.

Agonist activity at human FPR2 expressed in rat RBL-2H3 cells by intracellular Ca2+ mobilization assay

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
5.

Agonist activity against human FPR2 expressed in human HL60 cells by Fluo-4AM dye based intracellular Ca2+ mobilization assay

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
6.

Allosteric antagonist activity against FPR2 (unknown origin)

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
7.

Agonist activity at FPR2 in BALB/c mouse assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay relative to fMLF

Source:
ChEMBL
Protein Target:
Formyl peptide receptor-related sequence 1; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor related sequence 1; Formyl peptide receptor-like 1; Lipoxin A4 receptor; LXA4 receptor; N-formyl peptide receptor 2; N-formyl peptide receptor 3
8.

Agonist activity at FPR2 in BALB/c mouse assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay

Source:
ChEMBL
Protein Target:
Formyl peptide receptor-related sequence 1; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor related sequence 1; Formyl peptide receptor-like 1; Lipoxin A4 receptor; LXA4 receptor; N-formyl peptide receptor 2; N-formyl peptide receptor 3
9.

Agonist activity at FPR2 in human PMN assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay relative to fMLF in presence of probenecid

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
10.

Agonist activity at FPR2 in human PMN assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay relative to fMLF in absence of probenecid

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
11.

Agonist activity at FPR2 in human PMN assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay in presence of probenecid

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
12.

Agonist activity at FPR2 in human PMN assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay in absence of probenecid

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
13.

Agonist activity at human FPR2 transfected in human HL60 cells assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay relative to WKYMVm

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
14.

Agonist activity at human FPR1 transfected in human HL60 cells assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay relative to fMLF

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
15.

Agonist activity at human FPR2 transfected in human HL60 cells assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
16.

Agonist activity at human FPR1 transfected in human HL60 cells assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay

Source:
ChEMBL
Protein Target:
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
17.

Induction of calcium release in human FPR2 receptor-expressed HEK cell assessed as calcium release through Cav1.2 channel at 10 uM by cytosolic-free calcium assay in presence of 30 uM ATP

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
18.

Induction of calcium release in human FPR2 receptor-expressed HEK cell at 10 uM measured after second challenge by cytosolic-free calcium assay

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
19.

Induction of calcium release in mouse FPR2 receptor-expressed HEK cell by cytosolic-free calcium assay

Source:
ChEMBL
Protein Target:
Formyl peptide receptor-related sequence 1; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor related sequence 1; Formyl peptide receptor-like 1; Lipoxin A4 receptor; LXA4 receptor; N-formyl peptide receptor 2; N-formyl peptide receptor 3
20.

Induction of calcium release in human FPR2 receptor-expressed HEK cell by cytosolic-free calcium assay

Source:
ChEMBL
Protein Target:
N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
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