Format
Items per page
Sort by

Send to:

Choose Destination

Links from

Items: 1 to 20 of 91

1.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as iodide influx at 10 uM after 24 hrs by HS-YFP assay

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
2.

Potentiator activity at CFTR G551D mutant (unknown origin) expressed in rat FRT cells assessed as increase in iodine influx by HS-YFP assay

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
3.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as iodide influx after 24 hrs by HS-YFP assay

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
4.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodide influx after 24 hrs by HS-YFP assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
5.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as iodide influx after 24 hrs by HS-YFP assay relative to 1 uM VX-809

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
6.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodide influx after 24 hrs by HS-YFP assay

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
7.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodide influx after 24 hrs by HS-YFP assay relative to vehicle-treated control in presence of VX-809

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
8.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodide influx after 24 hrs by HS-YFP assay in presence of VX-809

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
9.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as iodide influx after 24 hrs by HS-YFP assay in presence of VX-809 and CFTR inhibitor 172

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
10.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in size of cAMP-dependent current at 10 uM after 24 hrs measured at +100 mV by whole cell patch clamp assay relative to vehicle-treated control

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
11.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as size of cAMP-dependent current at 10 uM after 24 hrs measured at +100 mV by whole cell patch clamp assay in presence of CFTRinh 172

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
12.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in size of cAMP-dependent current at 1 uM after 24 hrs measured at +100 mV by whole cell patch clamp assay

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
13.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in size of cAMP-dependent current at 10 uM after 24 hrs measured at +100 mV by whole cell patch clamp assay in presence of 1 uM VX-809

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
14.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in fully glycosylated protein by western blot analysis

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
15.

Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in fully glycosylated protein by western blot analysis in presence of VX-809

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
16.

Potentiator activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodine influx measured after 30 mins incubation following rescue of F508del-CFTR by low temperature for 24 hrs by HS-YFP assay

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
17.

Potentiator activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodine influx measured after 30 mins incubation following rescue of F508del-CFTR by low temperature for 24 hrs by HS-YFP assay relative to genistein

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
18.

Potentiator activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodine influx measured after 30 mins incubation following rescue of F508del-CFTR by low temperature for 24 hrs by HS-YFP assay relative to VX-770

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
19.

Cystic fibrosis transmembrane conductance regulator activator

Source:
ChEMBL
Protein Target:
Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel
AID:
1225137
20.

Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in HeLa Cells

Source:
Southern Research Institute
Protein Target:
cystic fibrosis transmembrane conductance regulator [Homo sapiens]
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Refine your results

• What's this?

Actions on your results

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center