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Items: 1 to 20 of 227

1.

Inhibition of human recombinant aminopeptidase N using AbzdR-G-L-EDDnp as substrate after 20 to 40 mins by fluorometry

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
2.

Inhibition of recombinant human Aminopeptidase N using L-Ala-beta-NA as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluorometry

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
3.

Inhibition of human APN

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
AID:
1236837
4.

Inhibition of human recombinant APN using L-Ala-beta-NA as substrate after 30 mins by fluorimetry

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
5.

Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
AID:
1162777
6.

Inhibition of APM (unknown origin) assessed as half-life of endomorphin-1 after 30 min by RP-HPLC analysis (Rvb = 19.7 +/- 0.5 min)

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
7.

Inhibition of APM (unknown origin) assessed as inhibition of endomorphin-1 degradation after 30 min

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
8.

Inhibition of APM (unknown origin) assessed as half-life of endomorphin-2 after 30 min by RP-HPLC analysis (Rvb = 23.3 +/- 0.98 min)

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
9.

Inhibition of APM (unknown origin) assessed as inhibition of endomorphin-2 degradation after 30 min

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
10.

Inhibition of aminopeptidase N (unknown origin)

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
11.

Inhibition of aminopeptidase N (unknown origin) using L-leucine-beta-naphthylamide as substrate after 15 mins

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
12.

Inhibition of APN in human ES-2 cells using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 1 hr by UV-Vis spectrophotometry

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
13.

Ratio of betastatin IC50 to compound IC50 for APN in human ES-2 cells

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
14.

Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by spectrophotometric analysis

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
15.

Inhibition of human APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectrophotometric analysis

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
AID:
738661
16.

Inhibition of APN-mediated HIF1alpha expression in human Caco2/TC7 cells at 0.1 to 1 uM after 48 hrs by Western blot analysis

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
17.

Inhibition of APN-mediated mTOR expression in human Caco2/TC7 cells assessed as decrease in pS6RP level at 0.1 to 1 uM after 48 hrs by Western blot analysis

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
18.

Inhibition of aminopeptidase N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by spectrophotometric analysis

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
19.

Inhibition of APN in human ES2 cell surface assessed as inhibition of L-Leu-p-nitroanilide substrate hydrolysis incubated for 5 mins before substrate addition by UV-Vis spectrophotometric analysis

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
20.

Inhibition of aminopeptidase in human ES-2 cells

Source:
ChEMBL
Protein Target:
Aminopeptidase N; AP-N; hAPN; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
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