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Items: 14

1.

Inhibition of CXCR6 (unknown origin) at 10 uM relative to control

Source:
ChEMBL
Protein Target:
C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD_antigen=CD186
2.

Binding affinity to CXCR6 (unknown origin) at 10 uM by radioligand displacement assay

Source:
ChEMBL
Protein Target:
C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD_antigen=CD186
3.

Antagonist activity at CXCR6 (unknown origin) assessed as inhibition of calcium flux at 10 uM

Source:
ChEMBL
Protein Target:
C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD_antigen=CD186
4.

Antagonist activity at CXCR6 (unknown origin) assessed as inhibition of chemotaxis at 10 uM

Source:
ChEMBL
Protein Target:
C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD_antigen=CD186
6.

SAR analysis of small molecule antagonists of the CXCR6 receptor in a screening panel assay - 4

Source:
Burnham Center for Chemical Genomics
Protein Targets:
C-X-C chemokine receptor type 5 isoform 1 [Homo sapiens]; ...
Total:
2
7.

SAR analysis of small molecule antagonists of the CXCR6 receptor in a screening panel assay - 3

Source:
Burnham Center for Chemical Genomics
Protein Targets:
C-C chemokine receptor type 6 [Homo sapiens]; ...
Total:
3
8.
9.
10.

Activity at human CXCR6 receptor at 10 uM

Source:
ChEMBL
Protein Target:
C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD_antigen=CD186
11.
13.

Summary assay for small molecule Inhibitors of CXCR6

Source:
Burnham Center for Chemical Genomics
Protein Target:
C-X-C chemokine receptor type 6 [Homo sapiens]
14.

uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay

Source:
Burnham Center for Chemical Genomics
Protein Target:
C-X-C chemokine receptor type 6 [Homo sapiens]
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