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Items: 1 to 20 of 34

1.

Cytochrome P450 11A1 inhibitor

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
2.

Drug metabolism assessed as bovine CYP11A1-mediated compound metabolism after 2 mins incubation using compound loaded phospholipid vesicle by reverse phase HPLC

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
3.

Mechanism based inhibition of bovine cytochrome P450 CYP11A1

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
5.

Inhibition of bovine adrenal cholesterol side chain cleavage(CSCC) cytochrome P450 11A1

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
6.

Stimulation of pregnenolone formation from rat C6 glioma cells

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
7.

Inhibition of P450 scc

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
8.

Inhibition of P450 scc at 25 uM

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
9.

Inhibition of bovine adrenal desmolase at 50 ug/mL; None

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
10.

Inhibition of bovine adrenal desmolase cytochrome P450 11A1 at 50 ug/mL

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
11.

Inhibition of bovine adrenal desmolase (IC50) relative to aminoglutethimide

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
12.

Inhibition of bovine adrenal desmolase at 25 uM

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
13.

Percent inhibition of Bovine Adrenal Desmolase in vitro; inhibition values ranging from +5 to -5

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
14.

Percent inhibition of Bovine Adrenal Desmolase in vitro using bovine adrenal mitochondria and cholesterol; Inhibition values ranging from +5 to -5

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
15.

Percent inhibition of Bovine Adrenal Desmolase in vitro (10.9 mg/kg); inhibition values ranging from +5 to -5

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
16.

Evaluated for percent inhibition of Bovine Adrenal Desmolase in vitro using bovine adrenal mitochondria and cholesterol

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
17.

Inhibition of bovine adrenal desmolase

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
18.

Competitive inhibition constant (Km) for bovine cholesterol side-chain cleavage desmolase cytochrome P450 11A1

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
19.

Inhibition of bovine cholesterol side-chain cleavage desmolase, cytochrome P450 11A1

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
20.

Inhibition of bovine cholesterol side-chain cleavage desmolase, cytochrome P450 11A1; none

Source:
ChEMBL
Protein Target:
Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
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