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Links from PubChem BioAssay

Items: 1 to 20 of 87

1.

Activation of human Kv7.2/7.3 expressed in CHOK1 cells assessed as increase in current amplitude relative to control

Source:
ChEMBL
Protein Targets:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2; ...
Total:
2
2.

Activation of human Kv7.2/7.3 expressed in CHOK1 cells

Source:
ChEMBL
Protein Targets:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2; ...
Total:
2
3.

Voltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3) activator

Source:
ChEMBL
Protein Targets:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2; ...
Total:
2
4.

Voltage-gated potassium channel subunit Kv7.2 activator

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
5.

Inhibition of KCNQ2 (unknown origin)

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
6.

Voltage-gated potassium channel subunit Kv7.2 activator

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
7.

Voltage-gated potassium channel blocker

Source:
ChEMBL
Protein Targets:
Potassium voltage-gated channel subfamily A member 10; Voltage-gated potassium channel subunit Kv1.8; ...
Total:
40
8.

Activity at rat KCNQ2 assessed as increase in channel current at 300 uM at -50 mV by whole-cell patch-clamp assay relative to control

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
9.

Activity at rat KCNQ2 assessed as increase in decay kinetics at 300 uM at -50 mV by whole-cell patch-clamp assay relative to control

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
10.

Activity at rat KCNQ2 assessed as increase in channel current at 750 uM at -50 mV by whole-cell patch-clamp assay relative to control

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
11.

Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
AID:
779736
12.

Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay relative to (+/-)-N-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)-3-(2-chlorophenyl)acrylamide

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
13.

Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay relative to retigabine

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
14.

KCNQ (Kv7) potassium channel blocker

Source:
ChEMBL
Protein Targets:
Potassium voltage-gated channel subfamily KQT member 1; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Voltage-gated potassium channel subunit Kv7.1; ...
Total:
5
15.

Positive modulatory activity at voltage-gated K channel 7.2 (unknown origin)

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
16.

Modulation of human KCNQ2/3 channel expressed in CHO-K1 cells by fluorescence assay relative to retigabine

Source:
ChEMBL
Protein Targets:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2; ...
Total:
2
17.

Modulation of human KCNQ2/3 channel expressed in CHO-K1 cells by fluorescence assay

Source:
ChEMBL
Protein Targets:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2; ...
Total:
2
18.

Activation of KCNQ2 channel expressed in CHO cells assessed as depolarization-induced thallium influx up to 30 uM after 3 mins by patch clamp assay relative to control

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
19.

Activation of KCNQ2 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay relative to control

Source:
ChEMBL
Protein Target:
Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2
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