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Items: 1 to 20 of 24979

1.

Inhibition of SIK2 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
2.

Inhibition of QIK (unknown origin) by Off-chip Mobility Shift Assay

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
3.

Inhibition of SNF1LK2 (unknown origin) assessed as residual activity at 1 uM by radiometric protein kinase assay

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
4.

Inhibition of SIK2 (unknown origin) assessed as remaining enzyme activity at 10 uM by radioactive [33P]-ATP filter binding assay

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
5.

Competitive binding affinity to SNF1LK2 (unknown origin) at 10 uM in presence of ATP relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
6.

Competitive binding affinity to QIK (unknown origin) at 10 uM in presence of ATP relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
7.

Inhibition of SNF1LK2 (unknown origin) at 10 uM relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
8.

Inhibition of SNF1LK2 (unknown origin) assessed as remaining activity at 10 uM relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
9.

Inhibition of SNF1LK2 (unknown origin) assessed as remaining activity at 1 uM relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
10.

Inhibition of SIK2 (unknown origin) assessed as remaining activity at 10 uM relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
11.

Inhibition of SIK2 (unknown origin) using [gamma-33P]ATP assessed as residual activity at 3 uM

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
12.

GSK_PKIS: SNF1LK2 (QIK) mean inhibition at 1 uM [Nanosyn]

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
13.

GSK_PKIS: SNF1LK2 (QIK) mean inhibition at 0.1 uM [Nanosyn]

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
14.

Binding constant for SIK2 kinase domain

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
15.

Binding constant for full-length SNF1LK2

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
16.

Binding affinity to human QIK at 10 uM relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK2; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2
17.

Inhibition of SIK1 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK1; Salt-inducible kinase 1; SIK-1; Serine/threonine-protein kinase SNF1-like kinase 1; Serine/threonine-protein kinase SNF1LK
18.

Inhibition of human recombinant SIK expressed Sf21 cells using CREBtide(CKRREILSRRPSYRK) substrate assessed as remaining enzyme activity at 1 uM after 90 mins relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK1; Salt-inducible kinase 1; SIK-1; Serine/threonine-protein kinase SNF1-like kinase 1; Serine/threonine-protein kinase SNF1LK
19.

Inhibition of human SIK assessed as enzyme activity at 1 uM relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK1; Salt-inducible kinase 1; SIK-1; Serine/threonine-protein kinase SNF1-like kinase 1; Serine/threonine-protein kinase SNF1LK
20.

Inhibition of human SIK

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase SIK1; Salt-inducible kinase 1; SIK-1; Serine/threonine-protein kinase SNF1-like kinase 1; Serine/threonine-protein kinase SNF1LK
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