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Items: 1 to 20 of 46

1.

Inhibition of T4 bacteriophage polynucleotide kinase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins

Source:
ChEMBL
Protein Target:
Polynucleotide kinase; PNK; Deoxynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase
2.
3.

Inhibition of T4 polynucleotide kinase using 5'-hydroxyl termini of DNA and [gamma-32ATP] after 30 mins by liquid scintillation counting

Source:
ChEMBL
Protein Target:
Polynucleotide kinase; PNK; Deoxynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase
4.

Inhibition of Enterobacteria phage T4 Polynucleotide kinase at 100 uM

Source:
ChEMBL
Protein Target:
Polynucleotide kinase; PNK; Deoxynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase
5.

Inhibition of T4 polynucleotide kinase upto 100 uM

Source:
ChEMBL
Protein Target:
Polynucleotide kinase; PNK; Deoxynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase
6.

Inhibition of T4 polynucleotide kinase at 100 uM relative to control

Source:
ChEMBL
Protein Target:
Polynucleotide kinase; PNK; Deoxynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase
7.

Inhibition of T4 polynucleotide kinase at 100 uM

Source:
ChEMBL
Protein Target:
Polynucleotide kinase; PNK; Deoxynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase
8.

Inhibition of PRP4 (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase PRP4 homolog; PRP4 kinase; PRP4 pre-mRNA-processing factor 4 homolog
9.

Binding constant for PRP4 kinase domain

Source:
ChEMBL
Protein Target:
Serine/threonine-protein kinase PRP4 homolog; PRP4 kinase; PRP4 pre-mRNA-processing factor 4 homolog
10.

Inhibition of RuvBL1 (unknown origin) at 10 uM

Source:
ChEMBL
Protein Target:
RuvB-like 1; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alpha; TAP54-alpha
11.

Inhibition of human recombinant his-tagged pontin expressed in Escherichia coli BL21 assessed as reduction in inorganic phosphate release after 10 mins by malachite green-based colorimetric assay

Source:
ChEMBL
Protein Target:
RuvB-like 1; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alpha; TAP54-alpha
12.

Inhibition of human recombinant his-tagged pontin expressed in Escherichia coli BL21 assessed as reduction in inorganic phosphate release at 100 uM after 10 mins by malachite green-based colorimetric assay

Source:
ChEMBL
Protein Target:
RuvB-like 1; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alpha; TAP54-alpha
13.

Luminescence-based cell-based late stage dose response assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)

Source:
The Scripps Research Institute Molecular Screening Center
Protein Target:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens]
14.

Luminescence-based cell-based high throughput dose response assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)

Source:
The Scripps Research Institute Molecular Screening Center
Protein Target:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens]
15.

Luminescence-based cell-based primary high throughput confirmation assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)

Source:
The Scripps Research Institute Molecular Screening Center
Protein Target:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens]
16.

Summary of the probe development effort to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)

Source:
The Scripps Research Institute Molecular Screening Center
Protein Target:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens]
17.

Luminescence-based cell-based primary high throughput screening assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)

Source:
The Scripps Research Institute Molecular Screening Center
Protein Target:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens]
18.

Isoleucyl-tRNA synthetase inhibitor

Source:
ChEMBL
Protein Target:
Isoleucine--tRNA ligase; Isoleucyl-tRNA synthetase; IleRS
19.

In vitro antibacterial activity against isoleucyl-tRNA synthetase from Staphylococcus aureus Oxford

Source:
ChEMBL
Protein Target:
Isoleucine--tRNA ligase; Isoleucyl-tRNA synthetase; IleRS
20.

Compound tested for the inhibition of Staphylococcus aureus Leucyl-tRNA synthetase

Source:
ChEMBL
Protein Target:
Isoleucine--tRNA ligase; Isoleucyl-tRNA synthetase; IleRS
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