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Items: 1 to 20 of 155

1.

Inhibition of human beta-glucocerebrosidase at 1 mM at pH 5.5 by spectrophotometry

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
2.

Inhibition of human beta-glucocerebrosidase at 1 mM at pH 7.0 by spectrophotometry

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
3.

Inhibition of human beta-glucocerebrosidase at pH 5.5 by spectrophotometry

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
4.

Inhibition of human beta-glucocerebrosidase at pH 7.0 by spectrophotometry

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
5.
6.
7.
8.
9.

Activation of human beta-glucocerebrosidase in normal human skin fibroblasts using 4-methylumbelliferyl beta-D glycopyranoside substrate assessed as 4-methylumbelliferone release at 10 to 60 uM after 96 hrs

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
10.

Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetry

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
11.

Inhibition of human lysosomal beta-glucocerebrosidase using 2,4-dinitrophenyl-beta-D-glucopyranoside as substrate by UV spectrophotometric analysis

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
12.

Inhibition of human lysosomal beta-glucocerebrosidase

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
AID:
1152618
13.

Increase of intracellular activity of beta-glucocerebrosidase in human N370S cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 500 uM after 4 days relative to control

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
14.

Increase of intracellular activity of beta-glucocerebrosidase in human N370S cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 50 uM after 4 days relative to control

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
15.

Increase of intracellular activity of beta-glucocerebrosidase in human N370S cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 250 uM after 4 days relative to control

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
16.
17.
18.
19.

Stabilization of human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assessed as remaining enzyme activity at 50 uM at 53 degC after 60 mins relative to control

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
20.

Inhibition of human recombinant imiglucerase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 30 mins at pH 5.2 before substrate addition measured after 10 mins

Source:
ChEMBL
Protein Target:
Glucosylceramidase; Beta-glucocerebrosidase; Acid beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Alglucerase; Imiglucerase
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