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Inhibition of Nitric Oxide Synthase, Neuronal (nNOS) at 10.0 M in the Eurofins Panlabs Safety Screen
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of human nNOS assessed as inhibition constant measured after 5 mins
Assay data:3 Active, 1 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant mouse nNOS overexpressed in Escherichia coli assessed as inhibition constant
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human nNOS assessed as reduction of L-[14C]arginine to L-[14C]-citrulline conversion
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human nNOS transfected in baculovirus infected Sf9 cells assessed as reduction of [3H]L-arginine conversion to [3H]L-citrulline by scintillation counter analysis
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human nNOS assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversion in presence of NADPH
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human nNOS assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversion
Inhibition of nNOS in human DLD-1 cells assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversion
Assay data:3 Active, 3 Activity ≤ 1 µM, 5 Tested
Inhibition of rat nNOS transfected in HEK293 cells assessed as inhibition constant
Inhibition of nNOS (unknown origin) assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversion
Inhibition of rat brain nNOS expressed in baculovirus-infected Sf9 cells Escherichia coli assessed as reduction of [3H]-arginine to [3H]-citrulline conversion
Inhibition of rat nNOS transfected in HEK293 cells assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversion by liquid scintillation counting analysis
Inhibition of human nNOS expressed in baculovirus infected Spodoptera frugiperda cell using L-arginine as substrate preincubated for 15 mins followed by substrate addition measured after 15 mins by oxyhaemoglobin assay
Inhibition of human nNOS
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 5 Tested
Inhibition of human nNOS assessed as dissociation constant
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of mouse nNOS
Inhibition of rat nNOS
Inhibition of human nNOS assessed as inhibition constant
Inhibition of rat brain nNOS expressed in baculovirus infected sf9 cells measured after 72 hrs
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