Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19126451.

GPCR beta-arrestin recruitment assay with target: GPR35 Assay Type: PRESTO-Tango Concentration: 0.00001

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:437 Tested

AID:: 1912645

Summary Related BioAssays by Target

Select item 17918012.

PRESTO-Tango GPCRome screening (GPR35)

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:1 Tested

AID:: 1791801

Summary Related BioAssays by Target

Select item 17754943.

Agonist activity at human GPR35 receptor by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:1 Tested

AID:: 1775494

Summary PubMed Citation Related BioAssays by Target

Select item 17754934.

Agonist activity at human GPR35 receptor by beta-arrestin assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:1 Tested

AID:: 1775493

Summary PubMed Citation Related BioAssays by Target

Select item 17754925.

Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as dynamic mass redistribution response measured for 60 mins by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1775492

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 17754916.

Agonist activity at human GPR35 receptor expressed in HEK293T cells co-expressing beta-arrestin2 assessed as induction of beta-arrestin2 recruitment by BRET assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested

AID:: 1775491

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 17754857.

Agonist activity at human GPR35 receptor expressed in CHO-K1 cells assessed as desensitization of zaprinast-induced DMR response preincubated for 1 hr followed by zaprinast stimulation by DMR desensitization assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:9 Active, 2 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested

AID:: 1775485

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 17754848.

Agonist activity at human GPR35 receptor expressed in CHO-K1 cells assessed as dynamic mass redistribution response by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:9 Active, 1 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested

AID:: 1775484

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 17754839.

Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as reduction in dynamic mass redistribution response in presence of GPR35 antagonist ML-145 by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:36 Active, 31 Activity ≤ 1 µM, 36 Tested

AID:: 1775483

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 177548210.

Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as desensitization of zaprinast-induced DMR response preincubated for 1 hr followed by zaprinast stimulation by DMR desensitization assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:34 Active, 25 Activity ≤ 1 µM, 35 Tested

AID:: 1775482

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 177548111.

Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as dynamic mass redistribution response by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:36 Active, 26 Activity ≤ 1 µM, 37 Tested

AID:: 1775481

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 169989812.

Agonist activity at GPR35 receptor (unknown origin) assessed as reduction in dynamic mass redistribution response of corresponding probe at 40 uM by DMR desensitization assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:1 Tested

AID:: 1699898

Summary PubMed Citation Related BioAssays by Target

Select item 157723013.

Allosteric modulation of human PK-tagged Gi/Go-coupled GPR35 expressed in CHOK1 cells assessed as induction of zaprinast-mediated beta-arrestin recruitment by pathhunter assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:2 Tested

AID:: 1577230

Summary PubMed Citation Related BioAssays by Target

Select item 146008514.

Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused GPR35 in human Tango GPR35-bla U2OS cells assessed as induction of TEV protease-tagged beta-arrestin recruitment incubated for 5 hrs by beta-lactamase reporter gene assay relative to zaprinast

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:8 Tested

AID:: 1460085

Summary PubMed Citation Related BioAssays by Target

Select item 146008415.

Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused GPR35 in human Tango GPR35-bla U2OS cells assessed as induction of TEV protease-tagged beta-arrestin recruitment incubated for 5 hrs by beta-lactamase reporter gene assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:7 Active, 3 Activity ≤ 1 µM, 8 Tested

AID:: 1460084

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 146008316.

Agonist activity at GPR35 in human HT-29 cells in presence of antagonist ML-145 by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:29 Tested

AID:: 1460083

Summary PubMed Citation Related BioAssays by Target

Select item 146008217.

Agonist activity at GPR35 in human HT-29 cells assessed as induction of cell desensitization to 1 uM zaprinast preincubated for 1 hr followed by zaprinast stimulation measured after 8 minutes by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:22 Active, 12 Activity ≤ 1 µM, 28 Tested

AID:: 1460082

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 146008118.

Agonist activity at GPR35 in human HT-29 cells by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:23 Active, 11 Activity ≤ 1 µM, 30 Tested

AID:: 1460081

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 146008019.

Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:8 Active, 3 Activity ≤ 1 µM, 10 Tested

AID:: 1460080

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 146007920.

Agonist activity at human GPR35 expressed in CHO-K1 cells by DMR assay

Source:: ChEMBL

Protein Target:: G-protein coupled receptor 35

Assay data:4 Active, 4 Activity ≤ 1 µM, 5 Tested

AID:: 1460079

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Proteins (21)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (76)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (3)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (42)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (72)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (139)
BioAssays extracted from the literature
NIH MLP (15)
BioAssays deposited by the NIH Molecular Libraries Program
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BioAssays deposited by other experimentalists

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