Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Turbidometric Assay from Article 10.3109/14756366.2013.777717: "Novel inhibitor of bacterial sphingomyelinase, SMY-540, developed based on three-dimensional structure analysis."
Assay data:4 Active, 12 Tested
SummaryCompounds, ActivePubMed Citation
Inhibitor Selectivity Assay from Article 10.1021/cb500917m: "Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV."
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
NaMNAT HPLC Enzyme Assay from Article 10.1021/cc9000357: "SAR studies for a new class of antibacterial NAD biosynthesis inhibitors."
Assay data:2 Active, 77 Tested
NADs HPLC Enzyme Assay from Article 10.1021/cc9000357: "SAR studies for a new class of antibacterial NAD biosynthesis inhibitors."
Assay data:1 Active, 80 Tested
Enzymatic Inhibition Assay from Article 10.1016/j.chembiol.2009.07.006: "Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD."
Assay data:2 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Fluorescence Resonance Energy Transfer (FRET) Assay from Article 10.1016/j.bmc.2009.08.067: "Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors."
Assay data:22 Active, 7 Activity ≤ 1 µM, 84 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
MAPKKide Assay from Article 10.1111/j.1747-0285.2007.00617.x: "Rhodanine derivatives as selective protease inhibitors against bacterial toxins."
Assay data:39 Active, 3 Activity ≤ 1 µM, 65 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Fluorescence Peptide Cleavage Assay from Article 10.1021/jm8013212: "Thioamide Hydroxypyrothiones Supersede Amide Hydroxypyrothiones in Potency against Anthrax Lethal Factor."
Assay data:6 Active, 28 Tested
Fluorescence Resonance Energy Transfer Assay (FRET) from Article 10.1016/j.bmcl.2006.07.005: "Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease."
Assay data:14 Active, 4 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Enzyme Inhibition Microplate Assay from Article 10.1021/jm0605132: "Novel small-molecule inhibitors of anthrax lethal factor identified by high-throughput screening."
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
HPLC Assay from Article 10.1021/jm0605132: "Novel small-molecule inhibitors of anthrax lethal factor identified by high-throughput screening."
Assay data:18 Active, 3 Activity ≤ 1 µM, 18 Tested
Fluorescence Resonance Energy Transfer Assay (FRET) from Article 10.1016/j.bmcl.2005.12.038: "Guanidinylated 2,5-dideoxystreptamine derivatives as anthrax lethal factor inhibitors."
Assay data:6 Active, 4 Activity ≤ 1 µM, 13 Tested
Fluorescence Resonance Energy Transfer Assay (FRET) from Article 10.1016/j.bmcl.2005.10.088: "The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection."
Assay data:39 Active, 28 Activity ≤ 1 µM, 50 Tested
Fluorescence Peptide Cleavage Assay from Article 10.1021/jm050892j: "Anthrax lethal factor protease inhibitors: synthesis, SAR, and structure-based 3D QSAR studies."
Assay data:10 Active, 16 Tested
Fluorescence Peptide Cleavage Assay from Article 10.1073/pnas.0502733102: "Efficient synthetic inhibitors of anthrax lethal factor."
Assay data:23 Active, 8 Activity ≤ 1 µM, 35 Tested
Antibacterial activity against Bacillus cereus ATCC 13061 incubated for 24 hrs by microtiter plate method
Assay data:7 Tested
SummaryPubMed Citation
Bacteriolytic activity against Bacillus cereus ATCC 10987 incubated for 2 hrs
Assay data:2 Active, 5 Tested
Antibacterial activity against Bacillus cereus ATCC 10987
Assay data:1 Tested
Bacteriostatic activity against Bacillus cereus ATCC 10987 assessed as inhibition of bacterial growth
Antimicrobial activity against Bacillus cereus ATCC 14579 assessed as inhibition of bacterial growth in presence of D11 incubated for 6 hrs
Assay data:1 Active, 1 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on