Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Fluorescence Polarization Assay from US Patent US20240218021: "CYCLIN INHIBITORS"
Assay data:676 Active, 672 Activity ≤ 1 µM, 677 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Biological Assay from US Patent US20230312583: "1H-IMIDAZO [4,5-H] QUINAZOLINE COMPOUND AS NOVEL SELECTIVE FLT3 INHIBITORS"
Assay data:21 Active, 11 Activity ≤ 1 nM, 21 Activity ≤ 1 µM, 21 Tested
CDK Kinase Assays from US Patent US11053238: "Benzimidazole derivatives, preparation methods and uses thereof"
Assay data:15 Active, 15 Activity ≤ 1 µM, 15 Tested
Kinase Inhibition Assay from Article 10.1074/jbc.M500805200: "Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives."
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Kinase Inhibition Assay from Article 10.1016/j.bmcl.2006.03.060: "Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors."
Assay data:11 Active, 2 Activity ≤ 1 µM, 11 Tested
Kinase Inhibition Assay from Article 10.1021/jm990506w: "Docking-based development of purine-like inhibitors of cyclin-dependent kinase-2."
Assay data:9 Active, 5 Activity ≤ 1 µM, 10 Tested
Kinase Inhibition Assay from Article 10.1021/jm9911130: "Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex."
Assay data:15 Active, 14 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Kinase Inhibition Assay from Article 10.1016/s0960-894x(00)00357-7: "Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1."
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Kinase Inhibition Assay from Article 10.1016/s0960-894x(98)00097-3: "Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases."
Assay data:17 Active, 9 Activity ≤ 1 µM, 17 Tested
Kinase Inhibition Assay from Article 10.1016/S0968-0896(02)00069-X: "Pyrazolo[3,4-b]quinoxalines. A new class of cyclin-dependent kinases inhibitors."
Assay data:5 Active, 1 Activity ≤ 1 µM, 17 Tested
Kinase Inhibition Assay from Article 10.1016/S0968-0896(99)00064-4: "Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors."
Assay data:19 Active, 9 Activity ≤ 1 µM, 31 Tested
CDK 1 Inhibition Assay from Article 10.1021/jm0108348: "Structure-based design and synthesis of 2-benzylidene-benzofuran-3-ones as flavopiridol mimics."
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Kinase Inhibition Assay from Article 10.1016/j.bmcl.2003.10.062: "1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3 beta."
Assay data:7 Active, 6 Activity ≤ 1 µM, 7 Tested
Kinase Inhibition Assay from Article 10.1021/jm058013g: "Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases."
Assay data:11 Active, 2 Activity ≤ 1 µM, 30 Tested
Kinase Inhibition Assay from Article 10.1021/jm049353p: "Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin."
Assay data:7 Active, 3 Activity ≤ 1 µM, 7 Tested
Kinase Inhibition Assay from Article 10.1016/j.bmcl.2004.10.091: "Novel CDK inhibition profiles of structurally varied 1-aza-9-oxafluorenes."
Assay data:12 Active, 2 Activity ≤ 1 µM, 23 Tested
Kinase Inhibition Assay from Article 10.1021/jm031016d: "Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases."
Assay data:32 Active, 31 Activity ≤ 1 µM, 38 Tested
Kinase Inhibition Assay from Article 10.1021/jm020319p: "Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects."
Assay data:40 Active, 18 Activity ≤ 1 µM, 51 Tested
Kinase Inhibition Assay from Article 10.1021/jm0308904: "Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones."
Assay data:18 Active, 13 Activity ≤ 1 µM, 23 Tested
Kinase Inhibition Assay from Article 10.1046/j.1432-1327.2000.01673.x: "Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25."
Assay data:45 Active, 36 Activity ≤ 1 µM, 56 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on