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Hemolytic activity in mammalian RBC assessed as hemolysis
Assay data:1 Tested
SummaryPubMed Citation
Hemolytic activity in mammalian RBC assessed as hemolysis at 320 ug/ml incubated for 1 hr by microplate reader analysis
Inhibition of mammalia NA+/K+ ATPase assessed as ATP hydrolysis incubated for 30 mins by colorimetric method
Assay data:11 Active, 1 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of mammalia H+ ATPase assessed as ATP hydrolysis incubated for 30 mins by colorimetric method
Assay data:1 Active, 1 Activity ≤ 1 µM, 15 Tested
Inhibition of mammalian GGTase-1 expressed in Sf9 cells using wildtype His-tagged RAS-CVLL as substrate assessed as inhibition of substrate plasma membrane localisation
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Competitive binding of mammalian GGTase-1 expressed in Sf9 cells assessed as inhibition of 3H-GGPP binding to RAS using Ras-CVLL as substrate incubated for 10 mins
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of mammalian alpha-amylase using starch as substrate
Cytotoxicity against mammalian NCTC cells
Stability against mammalian enzyme dehydropeptidase (calculated for 1 uL of enzyme solution and 100 uM substrate)
Stability against mammalian enzyme dehydropeptidase (calculated for 1 microL of enzyme solution and 100 uM substrate)
Stability against mammalian enzyme dehydropeptidase (calculated for 1 microL of enzyme solution and 100 uM substrate).
Assay data:3 Tested
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells
Assay data:69 Active, 1040 Tested
SummaryCompounds, Active
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH20)
Screen for compounds that attenuate mutant SOD1 toxicity (mSOD1)
Assay data:35 Active, 1040 Tested
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH100)
Cellular toxicity caused by inducible expressing of N-terminal huntingtin with expanded ployglutamine repeat (Htt-N63-148Q) in PC12 cells (ROSShtt)
Assay data:11 Active, 1040 Tested
Screen for compounds that inhibit mitochondrial permeability transition (MitoPT)
Assay data:10 Active, 1040 Tested
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