txid12721[Organism:noexp] - PubChem BioAssay - NCBI

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Select item 20368701.

Inhibition of HIV-1 integrase DTG-resistant R263K mutant

Source:: ChEMBL

Protein Target:: Integrase

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 2036870

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 20368682.

Inhibition of HIV-1 integrase G140S/Q148K double mutant

Source:: ChEMBL

Protein Target:: Integrase

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 2036868

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 20368603.

Inhibition of HIV-1 integrase Q148K mutant

Source:: ChEMBL

Protein Target:: Integrase

Assay data:1 Tested

AID:: 2036860

Summary PubMed Citation Related BioAssays by Target

Select item 20141114.

Inhibition of HIV protease

Source:: ChEMBL

Protein Target:: Protease

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2014111

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 20131535.

Substrate activity at HIV reverse transcriptase measured after 4 hrs by electrophoresis based primer extension assay

Source:: ChEMBL

Assay data:6 Active, 9 Tested

AID:: 2013153

Summary Compounds, Active PubMed Citation

Select item 19884356.

Antiviral activity against wild type HIV IIIB infected in human TZM-bl cells

Source:: ChEMBL

Assay data:6 Active, 5 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested

AID:: 1988435

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19792627.

Antiviral activity against HIV infected in MT4 cells assessed as viral replication

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1979262

Summary Compounds, Active PubMed Citation

Select item 19731178.

Inhibition of HIV reverse transcriptase in human CEM cells at 400 uM relative to control

Source:: ChEMBL

Assay data:1 Tested

AID:: 1973117

Summary PubMed Citation

Select item 19731039.

Antiviral activity against HIV assessed as inhibition of viral growth

Source:: ChEMBL

Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested

AID:: 1973103

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 197309910.

Antiviral activity against HIV RF assessed as inhibition of viral growth

Source:: ChEMBL

Assay data:2 Tested

AID:: 1973099

Summary PubMed Citation

Select item 197309811.

Antiviral activity against HIV infected in human MT4 cells by plaque reduction assay

Source:: ChEMBL

Assay data:3 Tested

AID:: 1973098

Summary PubMed Citation

Select item 197074312.

Antiviral activity against HIV LAI infected in human MT2 cells assessed as inhibition of viral growth

Source:: ChEMBL

Assay data:9 Active, 17 Activity ≤ 1 µM, 17 Tested

AID:: 1970743

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 139328413.

Inhibition of recombinant HIV protease expressed in inclusion bodies of Escherichia coli BL21 (DE3)

Source:: ChEMBL

Protein Target:: Protease

Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1393284

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 55413914.

Antiviral activity against HIV Ba-L infected in PBMC

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 554139

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 55357115.

Antiviral activity against HIV1 LAI infected in human MT2 cells after 7 days by MTT assay

Source:: ChEMBL

Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested

AID:: 553571

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 27050316.

Antiviral activity against HIV BaL in PM1 cell

Source:: ChEMBL

Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested

AID:: 270503

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 25750117.

Antiviral activity against mutant HIV isolate Q-60C

Source:: ChEMBL

Assay data:14 Active, 15 Activity ≤ 1 µM, 15 Tested

AID:: 257501

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 25750018.

Antiviral activity against mutant HIV isolate V-18C

Source:: ChEMBL

Assay data:14 Active, 15 Activity ≤ 1 µM, 15 Tested

AID:: 257500

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 25749919.

Antiviral activity against mutant HIV isolate K-60C

Source:: ChEMBL

Assay data:14 Active, 15 Activity ≤ 1 µM, 15 Tested

AID:: 257499

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 25749820.

Antiviral activity against 4X HIV strain

Source:: ChEMBL

Assay data:15 Active, 15 Activity ≤ 1 µM, 15 Tested

AID:: 257498

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

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Activity (IC50, etc) ≤ 1 nM (95)
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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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