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In Vitro Assay from US Patent US9315438: "Optically pure benzyl-4-chlorophenyl-C-glucoside derivative"
Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibitory Effect on the Sodium-dependent Glucose Co-Transporter SGLT, SGLT1 and SGLT2 from US Patent USRE49080: "Glycoside derivatives and uses thereof"
Assay data:35 Active, 11 Activity ≤ 1 nM, 35 Activity ≤ 1 µM, 35 Tested
SGLT1/2 in-vitro assay from US Patent US10752604: "C-glucoside derivative containing fused phenyl ring or pharmaceutically acceptable salt thereof, process for preparing same, and pharmaceutical composition comprising same"
Assay data:20 Active, 20 Activity ≤ 1 µM, 20 Tested
Inhibition Assay from US Patent US9505734: "Phenyl C-glucoside derivative containing deoxyglucose structure, preparation method and use thereof"
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SGLT2 Inhibition Assay from US Patent US9340521: "Method for dual inhibition of SGLT1 and SGLT2 using diphenylmethane derivatives"
Assay data:65 Active, 40 Activity ≤ 1 nM, 65 Activity ≤ 1 µM, 65 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Sodium-Dependent Glucose Transporter (SGLT) Assay from US Patent US9296775: "Pyrazole compounds"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition Assay from US Patent US9161945: "4-isopropyl-6-methoxyphenyl glucitol compound"
Inhibition Assay from US Patent US9034921: "Diphenylmethane derivatives as SGLT2 inhibitors"
Assay data:202 Active, 54 Activity ≤ 1 nM, 202 Activity ≤ 1 µM, 202 Tested
In Vitro Assay from US Patent US9006187: "Thiophene derivative as SGLT2 inhibitor and pharmaceutical composition comprising same"
Assay data:33 Active, 33 Activity ≤ 1 µM, 34 Tested
Uptake Assay from US Patent US8980829: "Aryl glycoside compound, preparation method and use thereof"
Assay data:25 Active, 25 Activity ≤ 1 µM, 25 Tested
Inhibition Assay from US Patent US8921412: "C-aryl ansa SGLT2 inhibitors"
Assay data:16 Active, 3 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 16 Tested
Inhibition Assay from US Patent US8614195: "Glycoside derivatives and uses thereof"
Assay data:11 Active, 11 Activity ≤ 1 µM, 11 Tested
Biological Assays from US Patent US8669380: "Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives"
Inhibition Assay from US Patent US8609622: "C-aryl glucoside derivatives, preparation process and pharmaceutical use thereof"
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
In Vitro Assay from US Patent US8575114: "SGLT-2 inhibitors, methods of making them, and uses thereof"
Assay data:22 Active, 22 Activity ≤ 1 µM, 22 Tested
Inhibition Assay from US Patent US8541380: "C-aryl glucoside SGLT2 inhibitors and pharmaceutical compositions comprising same"
Assay data:97 Active, 90 Activity ≤ 1 µM, 97 Tested
Inhibitory Activity Assay from US Patent US10011627: "C-aryl glucoside derivative, preparation methods thereof, and medical applications thereof"
Assay data:9 Active, 1 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested
SGLT2 and SGLT1 Inhibition from US Patent US10294259: "Phenyl c-glucoside derivative containing deoxyglucose structure, preparation method and use thereof"
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
SGLT Binding Assay from Article 10.1021/jm701272q: "Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes."
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In Vitro Human SGLT2 Inhibition Assay from US Patent US9688710: "Inhibitors of sodium glucose cotransporter 1"
Assay data:158 Active, 160 Activity ≤ 1 µM, 160 Tested
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