Homo sapiens APC regulator of WNT signaling pathway (APC), transcript - Nucleotide

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53. [PLoS One. 2024]
β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53.
Bourmoum M, Radulovich N, Sharma A, Tkach JM, Tsao MS, Pelletier L. PLoS One. 2024; 19(2):e0295030. Epub 2024 Feb 7.
APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation. [Cell Mol Life Sci. 2024]
APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation.
Zhang D, Ni QQ, Wang SY, He WF, Hong ZX, Liu HY, Chen XH, Chen LJ, Han FY, Zhang LJ, et al. Cell Mol Life Sci. 2024 Jan 27; 81(1):57. Epub 2024 Jan 27.
BET protein-dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer. [Cancer Lett. 2024]
BET protein-dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer.
Morino S, Mashima T, Shirai F, Nagayama S, Katayama R, Seimiya H. Cancer Lett. 2024 Mar 1; 584:216632. Epub 2024 Jan 11.

RefSeq alternative splicing
See 35 reference mRNA sequence splice variants for the APC gene.
RefSeq protein product
See the reference protein sequence for adenomatous polyposis coli protein isoform c (NP_001341825.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Order full-length cDNA clone [GeneCopoeia Inc.]
Order full-length cDNA clone
GeneCopoeia Inc.
UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser
Order APC cDNA clone/Protein/Antibody/RNAi [OriGene]
Order APC cDNA clone/Protein/Antibody/RNAi
OriGene

Your browsing activity is empty.

Activity recording is turned off.

Nucleotide