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Results: 1 to 10 of 26

1.

Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.

Vitucci M, Irvin DM, McNeill RS, Schmid RS, Simon JM, Dhruv HD, Siegel MB, Werneke AM, Bash RE, Kim S, Berens ME, Miller CR.

Neuro-oncology. 2017;

PubMed [journal]
PMID:
28398584
2.

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.

McNeill RS, Canoutas DA, Stuhlmiller TJ, Dhruv HD, Irvin DM, Bash RE, Angus SP, Herring LE, Simon JM, Skinner KR, Limas JC, Chen X, Schmid RS, Siegel MB, Van Swearingen AE, Hadler MJ, Sulman EP, Sarkaria JN, Anders CK, Graves LM, Berens ME, Johnson GL, Miller CR.

Neuro-oncology. 2017;

PubMed [journal]
PMID:
28379424
3.

Widespread Chromatin Accessibility at Repetitive Elements Links Stem Cells with Human Cancer.

Gomez NC, Hepperla AJ, Dumitru R, Simon JM, Fang F, Davis IJ.

Cell reports. 2016; 17(6):1607-1620. NIHMSID: NIHMS822119

PubMed [journal]
PMID:
27806299
PMCID:
PMC5267842
4.

Molecular classification of Crohn's disease reveals two clinically relevant subtypes.

Weiser M, Simon JM, Kochar B, Tovar A, Israel JW, Robinson A, Gipson GR, Schaner MS, Herfarth HH, Sartor RB, McGovern DP, Rahbar R, Sadiq TS, Koruda MJ, Furey TS, Sheikh SZ.

Gut. 2016; NIHMSID: NIHMS856544

PubMed [journal]
PMID:
27742763
PMCID:
PMC5426990
5.

Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses.

Simon JM, Davis JP, Lee SE, Schaner MR, Gipson GR, Weiser M, Sartor RB, Herfarth HH, Rahbar R, Sadiq TS, Koruda MJ, McGovern DP, Lieb JD, Mohlke KL, Furey TS, Sheikh SZ.

European journal of immunology. 2016; 46(8):1912-25. NIHMSID: NIHMS833510

PubMed [journal]
PMID:
27159132
PMCID:
PMC5486994
6.

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

Schmid RS, Simon JM, Vitucci M, McNeill RS, Bash RE, Werneke AM, Huey L, White KK, Ewend MG, Wu J, Miller CR.

Neuro-oncology. 2016; 18(7):962-73.

PubMed [journal]
PMID:
26826202
PMCID:
PMC4896545
7.

An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.

Souroullas GP, Jeck WR, Parker JS, Simon JM, Liu JY, Paulk J, Xiong J, Clark KS, Fedoriw Y, Qi J, Burd CE, Bradner JE, Sharpless NE.

Nature medicine. 2016; 22(6):632-40. NIHMSID: NIHMS773752

PubMed [journal]
PMID:
27135738
PMCID:
PMC4899144
8.

Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.

Pearson BL, Simon JM, McCoy ES, Salazar G, Fragola G, Zylka MJ.

Nature communications. 2016; 7:11173.

PubMed [journal]
PMID:
27029645
PMCID:
PMC4821887
9.

High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility.

Pattenden SG, Simon JM, Wali A, Jayakody CN, Troutman J, McFadden AW, Wooten J, Wood CC, Frye SV, Janzen WP, Davis IJ.

Proceedings of the National Academy of Sciences of the United States of America. 2016; 113(11):3018-23.

PubMed [journal]
PMID:
26929321
PMCID:
PMC4801272
10.

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.

Mabb AM, Simon JM, King IF, Lee HM, An LK, Philpot BD, Zylka MJ.

PloS one. 2016; 11(5):e0156439.

PubMed [journal]
PMID:
27231886
PMCID:
PMC4883752
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