darapladib [Supplementary Concept]

a selective lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) inhibitor, on biomarkers of cardiovascular (CV) risk

Date introduced: May 21, 2008

MeSH Unique ID: C529040

Registry Number: UI1U1MYH09

Heading Mapped to:

• Biphenyl Compounds
• Diethylamines
• Pyrimidinones
• Sulfides

Entry Terms:

• N-(2-(diethylamino)ethyl)-2-(2-((4-fluorobenzyl)sulfanyl)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopentapyrimidin-1-yl)-N-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)acetamide
• SB-480848

Pharmacologic Action:

• Phospholipase A2 Inhibitors