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Items: 5

1.

Tokyo

Capital of the country of JAPAN.

Year introduced: BONIN ISLANDS was see JAPAN 1975-1983

2.

Spectrin Tokyo [Supplementary Concept]

spectrin variant with a truncated beta chain with serine 2060 replaced by alanine; associated with elliptocytosis and moderate uncompensated hemolysis

Date introduced: November 17, 1992

3.

hemoglobin F-Tokyo [Supplementary Concept]

Val replaces Ile at position alpha2Ggamma2 34(B16)

Date introduced: July 12, 1985

4.

TCCSG B-8801 protocol [Supplementary Concept]

chemotherapy protocol consisting of above cpds; has 3 variations (Blocks); Block1 also contains cytarabine, Block2 also contains cytarabine, vincristine & enocytabine. Block3 also contains vincristine; used for treatment of B-cell-type lymphoma associated with Bloom's syndrome

Date introduced: August 20, 1992

5.

fibrinogen Tokyo II [Supplementary Concept]

abnormal fibrinogen with mutation in the D domain of the fibrin polymerization site

Date introduced: October 12, 1983

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