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The spinal or vertebral column.


Osteoarthritis, Spine

A degenerative joint disease involving the SPINE. It is characterized by progressive deterioration of the spinal articular cartilage (CARTILAGE, ARTICULAR), usually with hardening of the subchondral bone and outgrowth of bone spurs (OSTEOPHYTE).

Year introduced: 2009


Rigid spine syndrome [Supplementary Concept]

Date introduced: August 25, 2010


Spinal Dysraphism

Congenital defects of closure of one or more vertebral arches, which may be associated with malformations of the spinal cord, nerve roots, congenital fibrous bands, lipomas, and congenital cysts. These malformations range from mild (e.g., SPINA BIFIDA OCCULTA) to severe, including rachischisis where there is complete failure of neural tube and spinal cord fusion, resulting in exposure of the spinal cord at the surface. Spinal dysraphism includes all forms of spina bifida. The open form is called SPINA BIFIDA CYSTICA and the closed form is SPINA BIFIDA OCCULTA. (From Joynt, Clinical Neurology, 1992, Ch55, p34)

Year introduced: 1991(1964)


Spinal Osteochondrosis

A bone disorder involving ossification centers (EPIPHYSES) of the VERTEBRAL COLUMN.

Year introduced: 2009


Scheuermann Disease

A type of juvenile osteochondrosis affecting the fibrocartilaginous disc (INTERVERTEBRAL DISC) in the thoracic or thoracolumbar region of the SPINE. It is characterized by a forward concave SPINAL CURVATURE or KYPHOSIS.

Year introduced: 2009(1963)


Dendritic Spines

Spiny processes on DENDRITES, each of which receives excitatory input from one nerve ending (NERVE ENDINGS). They are commonly found on PURKINJE CELLS and PYRAMIDAL CELLS.

Year introduced: 2005


Camptocormia [Supplementary Concept]

Abnormal flexion of the thoracolumbar spine that is greater than 45 degrees anterior (forward bending). It often occurs in older individuals with neurlogic or muscular conditions such as AMYOTROPHIC LATERAL SCLEROSIS or PARKINSON DISEASE.

Date introduced: August 25, 2010


Ossification of the posterior longitudinal ligament of the spine [Supplementary Concept]

A hereditary ossification of the longitudinal spinal ligament (cervical and thoracic spine) that is common in Japanese and Asian populations in persons over 50 years of age. Patients may present with SPINAL CORD COMPRESSION; MYELOPATHY, and HYPERREFLEXIA. OMIM: 602475

Date introduced: August 25, 2010


Preso protein, rat [Supplementary Concept]

RefSeq XM_228906

Date introduced: November 15, 2012


Sipa1l1 protein, mouse [Supplementary Concept]

RefSeq NM_001167983

Date introduced: September 14, 2009


SIPA1L1 protein, human [Supplementary Concept]

RefSeq NM_015556

Date introduced: December 8, 2008


Sipa1l1 protein, rat [Supplementary Concept]

RefSeq NM_139330

Date introduced: December 15, 2003

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