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1.

Phosphorylation

The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.

Year introduced: 1991(1979)

2.
3.

Oxidative Phosphorylation

Electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds.

Year introduced: 1966

4.

Dyrk Kinases

PROTEIN KINASES that can phosphorylate aromatic amino acid residue TYROSINE as well as aliphatic amino acid residues SERINE and THREONINE.

Year introduced: 2024 (1996)

5.

P-type ATPases

A highly conserved family of ATPases that facilitate the transport of lipids and cations across the plasma membrane. Structurally, they are elongated ALPHA-HELICES constituting five functionally distinct domains: three cytoplasmic domains A, N, and P which contain the catalytic sites, and two transmembrane domains. The N domain phosphorylates the P-domain at an invariant ASPARTATE residue, which, in turn, is dephosphorylated by the A domain. The phosphorylation and dephosphorylation cycles drive conformational changes in the protein between two states (E1 and E2), which allow the substrate to access the other side of the membrane.

Year introduced: 2018

6.

Antibodies, Phospho-Specific

Antibodies directed against immunogen-coupled phosphorylated PEPTIDES corresponding to amino acids surrounding the PHOSPHORYLATION site. They are used to study proteins involved in SIGNAL TRANSDUCTION pathways. (From Methods Mol Biol 2000; 99:177-89)

Year introduced: 2004

7.

Mitochondrial Diseases

Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.

Year introduced: 2002

8.

Photophosphorylation

The use of light to convert ADP to ATP without the concomitant reduction of dioxygen to water as occurs during OXIDATIVE PHOSPHORYLATION in MITOCHONDRIA.

Year introduced: 1974(1972)

9.

DYRK3 protein, mouse [Supplementary Concept]

RefSeq NM_145508

Date introduced: April 17, 2013

10.

Combined Oxidative Phosphorylation Deficiency 5 [Supplementary Concept]

mutation in MRPS22

Date introduced: November 5, 2012

11.
12.

Combined Oxidative Phosphorylation Deficiency 3 [Supplementary Concept]

mutation in TSFM

Date introduced: November 5, 2012

13.
14.
15.

Ccdc88a protein, mouse [Supplementary Concept]

RefSeq NM_176841

Date introduced: August 31, 2005

16.

CCDC88A protein, human [Supplementary Concept]

RefSeq NM_017571

Date introduced: July 31, 2005

17.

PHAX protein, human [Supplementary Concept]

RefSeq NM_032177

Date introduced: July 29, 2005

18.

Cabyr protein, mouse [Supplementary Concept]

RefSeq NM_181731

Date introduced: August 6, 2004

19.

CABYR protein, human [Supplementary Concept]

RefSeq NM_153770

Date introduced: March 8, 2002

20.

DYRK3 protein, human [Supplementary Concept]

RefSeq NM_003582

Date introduced: May 22, 2000

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