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1.

Neurokinin A

A mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in structure and action to SUBSTANCE P and NEUROKININ B with the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the BRONCHI.

Year introduced: 1994

2.

neurokinin A, iodoHis(3)- [Supplementary Concept]

Date introduced: February 25, 1992

3.

Receptors, Neurokinin-2

A class of cell surface receptors for tachykinins that prefers neurokinin A; (NKA, substance K, neurokinin alpha, neuromedin L), neuropeptide K; (NPK); or neuropeptide gamma over other tachykinins. Neurokinin-2 (NK-2) receptors have been cloned and are similar to other G-protein coupled receptors.

Year introduced: 1994

4.
5.

neurokinin A, iodoHis(2)- [Supplementary Concept]

Date introduced: November 27, 1995

6.

neurokinin A (4-10), Lys(5)-MeLeu(9)-Nle(10)- [Supplementary Concept]

a selective NK-2 receptor agonist

Date introduced: October 22, 1993

7.

neurokinin A (4-10), Lys(5)-Tyr(I2)(7)-MeLeu(9)-Nle(10)- [Supplementary Concept]

a radioligand selective for the tachykinin NK2 receptor

Date introduced: May 6, 1993

8.

neurokinin A, Leu(9)- [Supplementary Concept]

Date introduced: January 5, 1993

9.
10.

neurokinin A(4-10), Tyr(5)-Trp(6,8,9)-Lys(10)- [Supplementary Concept]

tachykinin receptor antagonist

Date introduced: July 10, 1991

11.

neurokinin A (3-10), lysyl(3)-glycyl(8)-R-lactam-leucine(9)- [Supplementary Concept]

neurokinin receptor agonist

Date introduced: April 26, 1991

12.

MDL 28564 [Supplementary Concept]

Date introduced: November 9, 1990

13.
14.

neurokinin A (4-10), beta-Ala(8)- [Supplementary Concept]

selective NK-2 tachykinin receptor

Date introduced: June 23, 1990

15.
16.
17.

neurokinin A (4-10), Trp(7)-beta-Ala(8)- [Supplementary Concept]

a selective NK-2 receptor antagonist

Date introduced: May 30, 2000

18.

propionyl neurokinin A [Supplementary Concept]

Date introduced: August 1, 1994

19.

neurokinin A (4-10)-OH [Supplementary Concept]

the C-terminal free acid derivative of neurokinin A (4-10)

Date introduced: February 18, 1993

20.

neurokinin A-OH [Supplementary Concept]

the C-terminal free acid derivative of neurokinin A

Date introduced: February 18, 1993

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