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Items: 17

1.

Measles

A highly contagious infectious disease caused by MORBILLIVIRUS, common among children but also seen in the nonimmune of any age, in which the virus enters the respiratory tract via droplet nuclei and multiplies in the epithelial cells, spreading throughout the MONONUCLEAR PHAGOCYTE SYSTEM.

2.

Measles-Mumps-Rubella Vaccine

A combined vaccine used to prevent MEASLES; MUMPS; and RUBELLA.

Year introduced: 2001

3.

Measles virus

The type species of MORBILLIVIRUS and the cause of the highly infectious human disease MEASLES, which affects mostly children.

4.

Measles Vaccine

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)

Year introduced: 1964

5.

hemagglutinin protein G, measles virus [Supplementary Concept]

79,000 MW measles virion membrane glycoprotein isolated from purified measles virus; amino acid sequence given in second source

Date introduced: December 29, 1981

6.

Rubella

An acute infectious disease caused by the RUBELLA VIRUS. The virus enters the respiratory tract via airborne droplet and spreads to the LYMPHATIC SYSTEM.

7.

Viral Fusion Proteins

Proteins, usually glycoproteins, found in the viral envelopes of a variety of viruses. They promote cell membrane fusion and thereby may function in the uptake of the virus by cells.

Year introduced: 1987

8.

Subacute Sclerosing Panencephalitis

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Year introduced: 1971

9.

Rubella virus

The type (and only) species of RUBIVIRUS causing acute infection in humans, primarily children and young adults. Humans are the only natural host. A live, attenuated vaccine is available for prophylaxis.

Year introduced: 1966

10.
11.

C protein, measles virus [Supplementary Concept]

Date introduced: November 15, 2013

12.

CD46 protein, human [Supplementary Concept]

RefSeq NM_172361

Date introduced: July 29, 2005

13.

V protein, measles virus [Supplementary Concept]

amino acid sequence has been determined

Date introduced: July 10, 1991

14.

nucleoprotein, Measles virus [Supplementary Concept]

amino acid sequence given in first source

Date introduced: February 21, 1989

15.
16.

measles, mumps, rubella, varicella vaccine [Supplementary Concept]

combination vaccine

Date introduced: November 3, 1986

17.

P gene protein, measles virus [Supplementary Concept]

from rodent brain-adapted measles virus, plays a critical role in neurovirulence

Date introduced: August 3, 2017

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