Lewy Bodies

Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of injured or fragmented neurons. The presence of Lewy bodies is the histological marker of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may be seen in other neurological conditions. They are typically found in the substantia nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic nuclei, and neocortex.

Year introduced: 1992

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Tree Number(s): A11.284.420.460

MeSH Unique ID: D016631

Entry Terms:

• Lewy Body
• Lewy Neurites
• Lewy Neurite
• Neurite, Lewy

Previous Indexing:

• Cellular Inclusions (1972-1991)
• Cytoplasmic Granules (1966-1991)

See Also:

• Synucleinopathies
• Parkinson Disease
• Lewy Body Disease

All MeSH Categories
Anatomy Category
Cells
Cellular Structures
Inclusion Bodies
Lewy Bodies