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  • The following terms were not found in MeSH: Howard, Bary.

Genetic Diseases, Y-Linked

Genetic diseases that are linked to mutant ALLELES on the Y CHROMOSOME in humans (Y CHROMOSOME, HUMAN) or the Y chromosome in other species. Included here are animal models of human Y-linked diseases.

Year introduced: 2006


Sex-Determining Region Y Protein

A transcription factor that plays an essential role in the development of the TESTES. It is encoded by a gene on the Y chromosome and contains a specific HMG-BOX DOMAIN that is found within members of the SOX family of transcription factors.

Year introduced: 2006(1990)


Y-Box-Binding Protein 1

A CCAAT-enhancer-binding protein that was originally identified as interacting with Y-box PROMOTER REGIONS of MHC CLASS II GENES. It is a highly conserved transcription factor that regulates expression of a wide variety of GENES.

Year introduced: 2006(1984)


Genes, Y-Linked

Genes that are located on the Y CHROMOSOME.

Year introduced: 2006


Neisseria meningitidis, Serogroup Y

Strains of Neisseria meningitidis which, in the United States, causes disease in mostly adults and the elderly. Serogroup Y strains are associated with PNEUMONIA.

Year introduced: 2003


Receptors, Neuropeptide Y

Cell surface proteins that bind neuropeptide Y with high affinity and trigger intracellular changes which influence the behavior of cells.

Year introduced: 1993


Neuropeptide Y

A 36-amino acid peptide present in many organs and in many sympathetic noradrenergic neurons. It has vasoconstrictor and natriuretic activity and regulates local blood flow, glandular secretion, and smooth muscle activity. The peptide also stimulates feeding and drinking behavior and influences secretion of pituitary hormones.

Year introduced: 1987


H-Y Antigen

A sex-specific cell surface antigen produced by the sex-determining gene of the Y chromosome in mammals. It causes syngeneic grafts from males to females to be rejected and interacts with somatic elements of the embryologic undifferentiated gonad to produce testicular organogenesis.

Year introduced: 1979


Chromosomes, Human, 21-22 and Y

The short, acrocentric human chromosomes, called group G in the human chromosome classification. This group consists of chromosome pairs 21 and 22 and the Y chromosome.

Year introduced: 2001(1968)


Anastomosis, Roux-en-Y

A Y-shaped surgical anastomosis of any part of the digestive system which includes the small intestine as the eventual drainage site.

Year introduced: 1988


Chromosomes, Human, Y

The human male sex chromosome, being the differential sex chromosome carried by half the male gametes and none of the female gametes in humans.

Year introduced: 2003


Amino Acid Transport System y+L

A leucine-sensitive amino acid transport system with high affinity for basic amino acids( AMINO ACIDS, BASIC).

Year introduced: 2002


Amino Acid Transport System y+

A sodium-independent, basic amino acid transport system with a high-affinity for LYSINE; ARGININE; and ORNITHINE.

Year introduced: 2002


Y Chromosome

The male sex chromosome, being the differential sex chromosome carried by half the male gametes and none of the female gametes in humans and in some other male-heterogametic species in which the homologue of the X chromosome has been retained.

Year introduced: 1984(1978)


Genes, sry

The primary testis-determining gene in mammalians, located on the Y CHROMOSOME. It codes for a high mobility group box transcription factor (TRANSCRIPTION FACTORS) which initiates the development of the TESTES from the embryonic GONADS.

Year introduced: 2002



Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.

Year introduced: 1963


Male sterility due to Y-chromosome deletions [Supplementary Concept]

Male infertility or reduced fertility that is caused by deletions in the Y chromosome.

Date introduced: August 25, 2010


Dyrk kinase [Supplementary Concept]

85% identical to Mnb protein kinase from Drosophila; acts on both tyrosine and serine/threonine groups

Date introduced: June 28, 1996


HMGA1a Protein

An 11-kDa AT-hook motif-containing (AT-HOOK MOTIFS) protein that binds to the minor grove of AT-rich regions of DNA. It is the full-length product of the alternatively-spliced HMGA1 gene and may function as an architectural chromatin binding protein that is involved in transcriptional regulation.

Year introduced: 2002


Y 27632 [Supplementary Concept]

RN given for di-HCl salt; inhibits Rho-associated protein kinase; inhibits calcium sensitization to affect smooth muscle relaxation; structure in first source

Date introduced: November 17, 1997

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