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Fibrinogen

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

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Subheadings:

Tree Number(s): D12.776.124.050.250, D12.776.124.125.500, D12.776.811.300, D23.119.490

MeSH Unique ID: D005340

Registry Number: 9001-32-5

Entry Terms:

  • Blood Coagulation Factor I
  • Coagulation Factor I
  • Factor I, Coagulation
  • Factor I
  • gamma-Fibrinogen
  • gamma Fibrinogen

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