Erythromycin Estolate

A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.

Year introduced: 1991(1975)

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Tree Number(s): D02.540.576.500.992.250

MeSH Unique ID: D004918

Registry Number: XRJ2P631HP

Entry Terms:

• Estolate, Erythromycin
• Erythromycin Propionate Lauryl Sulfate
• Erythromycin Propionate Monododecyl Sulfate
• Erythromycin Propionate Dodecyl Sulfate
• Ilosone
• Lauromicina
• Eromycin

Previous Indexing:

• Erythromycin (1970-1974)
• Propionates (1974)
• Sodium Dodecyl Sulfate (1974)

Pharmacologic Action:

• Anti-Bacterial Agents
• Enzyme Inhibitors
• Gastrointestinal Agents
• Protein Synthesis Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Lactones
Polyketides
Macrolides
Erythromycin
Erythromycin Estolate